September 17, 2019
John Tomich to present Biochemistry and Molecular Biophysics Seminar Sept. 18
John Tomich, professor of biochemistry and molecular biophysics and director of the biotechnology/proteomics core facility at K-State, is the featured speaker for Biochemistry and Molecular Biophysics Seminar on Wednesday, Sept. 18. He will present "Branched Amphipathic peptide coated magnetic nanoparticles: Tissue distribution in vivo and, cellular uptake and cytokine activation in cultured epithelia and macrophage" at 4 p.m. in 120 Ackert Hall.
Presentation: Over the past few years our lab has been developing methods to deliver conventional small molecule drugs as well as well as nucleic acids to both aid and destroy cells/organisms in agricultural settings. Our most recent work has focused on examining the effects of our nano-carriers both in vitro and in vivo. These studies are required to move these delivery devices from the bench to use in the environment where off-target effects could cause harm. In this talk, in vitro and in vivo data will be presented discussing the safety and biodistribution of our delivery systems. Experiments documenting cellular uptake, cytotoxicity and immune responses will be presented.