Biochemistry and Molecular Biophysics Graduate Group Faculty
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Regulation of protein biosynthesis, Yeast genetics and biochemistry, Molecular and cell biology of insects and cancer |
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Molecular interactions between plant and parasites, Host plant resistance, Effectors and effector-triggered signaling pathways, wheat breeding and gene editing. |
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Biochemistry of triacylglycerol biosynthesis; structure and function of membrane bound acyltransferases; genetically modifying the physical properties of seed oils for industrial and biofuel applications. |
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Regulation of sodium and chloride transport by epithelial cells, with a focus on the functional interactions between the epithelial sodium channel (ENaC) and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). |
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Lyme Disease Pathogenesis, Mechanisms of Bacterial Immune Evasion, Protein Structure-Function, Drug Discovery. |
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Innate Immunity; Molecular Basis of Infectious Diseases and Host-Pathogen Interactions; Structural Biology and Molecular Recognition |
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Mechanisms that underly muscle structure and function. |
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Pathogenic microbiology and bacterial genetics. |
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Understanding the mechanisms of aging and developing clinically relevant drugs to delay aging and enhance human health and longevity. |
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Insect biochemistry and molecular biology; structure and function of hemolymph serine proteinases, proteinase inhibitors, and antibacterial response proteins from insects; biochemistry of insect cuticle sclerotization. |
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Iron acquisition by active transport through the cell envelopes of bacteria; Immunological approaches to bacterial pathogenesis; Biophysical analyses of bacterial membrane transport in living cells. |
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Regulation of mosquito innate immunity; malaria parasite-mosquito interactions. |
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Structural characterization and molecular recognition using Nuclear Magnetic Resonance (NMR) and Computer Aided Molecular Design (CAMD). |
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Synthetic organic chemistry; Drug discovery and selective delivery; Medicinal chemistry; Chemical biology. |
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Biomolecule phase separation; Amyloid fibril formation; Drug formulations; Self-assembly. |
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Plant molecular biology, developmental biology, plant sterols, START domains, sterols and cellulose; broadly focusing on deciphering the molecular mechanisms underlying growth and development of flowering plants. |
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Understanding the physiological regulation of epithelial ion transport and barrier functions. |
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Computer simulation of the structure and dynamics of peptides, proteins and nucleic acids; cosolvent effects on peptides and proteins; modeling of opioid peptides and their receptors. |
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Human Papillomavirus; Viral Oncogenesis; DNA Damage Repair |
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Developing and implementing mass-spectrometry-based lipid profiling strategies to understand the roles of particular lipids, as well as genes and proteins involved in lipid metabolism and lipid signaling. |
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Cell adhesion molecules and their role in cell growth and differentiation. |
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Protein structure and function, protein folding and aggregation, molecular chaperones and cellular stress. |