Ryan J. Rafferty

Dr. Ryan J. Rafferty

Associate Professor
location CBC 203
phone 785-532-6624 (office)
email rjraff@ksu.edu
Research Themes

Design and Synthesis of Molecules and Supramolecular Architecturesblank spacerFunctional Materials, Catalysis, and Nanochemistryblank spacerDesign and Synthesis of Molecules and Supramolecular Architectures

Lab Website Link


Associate Professor
Assistant Professor
Postdoctoral Researcher, University of Illinois at Urbana
Visiting Lecturer of Organic Chem., Univ. of Illinois at Urbana
Ph.D., Synthetic Organic Chemistry, Colorado State Univ.
Visiting Lecturer of Organic Chem., Colorado State Univ.
M.S., Biochemistry, University of Northern Colorado
B.S., Biology, University of Northern Colorado
B.A., Chemistry (Biochemistry Emphasis), University of Northern Colorado

Research Overview

Dr. Rafferty's research focuses in synthetic organic chemistry, drug discovery, medicinal chemistry, probing the transport of small molecules across complex cellular barriers, and the development of personalized cancer therapeutics. Students and postdoctoral fellows that join the group will receive training at the interface of chemistry and biology through the acquired skills and combinations of synthetic organic chemistry, medicinal chemistry, and chemical biology.

Selected publications

  • Rafferty, R.J., Hicklin, R. W., Maloof, K. A., and Hergenrother, P. J. “Synthesis of Complex and Diverse Compounds via Ring Distortion of Abietic Acid.” Angew. Chem. Int. Ed. 2014, 53, 220-224.
  • Rafferty, R. J. and Williams, R. W. “Formal Synthesis of Hapalindole O and Efforts Towards Ambiguine A.” Heterocycles, 2012, 86, 219-231.
  • Rafferty, R. J. and Williams, R. W. “Total Synthesis of Hapalindoles J and U.J. Org. Chem. 2012, 77, 519-524.
  • Rafferty, R. J. and Williams, R. W. “Synthetic Studies on the Ambiguine Family of Alkaloids: Construction of the ABCD Ring System.” Tet. Lett.2011, 52(17), 2037.
  • Artman, G.; Rafferty, R. J.; Williams, R. M. “(3R,7aS)-3-(Trichloromethyl)tetrahydro-pyrrolo[1,2-c]oxazol-1(3H)-one: An Air and Moisture Stable Reagent for the Synthesis of Optically Active a-Branched Prolines.” Org. Syn. 2009, 86, 262.