October 13, 2016
Division of Biology Seminar Oct. 14
Theodore White, professor and dean of the School of Biological Sciences at the University of Missouri, Kansas City, will present "The Ins and Outs of Antifungal Drug Resistance" as part of the Division of Biology Seminar Series at 4 p.m. Friday, Oct. 14, in 221 Ackert Hall.
White's lecture will provide a cross section of issues that contribute to antifungal drug resistance in pathogenic fungi. White will discuss the basic mechanisms, the transcriptional regulators and generalized mechanisms across funal species. He will present current understanding of how a series of 17 clinical isolates developed high level resistance.
White also will discuss his recent work on how Azole antifungals are imported into cells, and genes in the ergosterol pathway and their contributions to antifungal resistance and to the responses to other environmental stressors.