April 5, 2021
Bruce Schultz to present Anatomy and Physiology Seminar
Bruce Schultz, professor in the anatomy and physiology department at the College of Veterinary Medicine, will present "New therapies do not rescue bicarbonate secretion in cystic fibrosis" at the next Anatomy and Physiology Seminar at 4 p.m. Tuesday, April 6, via Zoom.
Schultz's research efforts are centered on understanding the physiological regulation of epithelial ion transport and barrier functions. Transepithelial movement of ions provides for electrolyte and fluid homeostasis and, in the case of milk, is necessary for production. Dysfunction of epithelial transport mechanisms, especially the anion channel that is mutated to cause cystic fibrosis, the cystic fibrosis transmembrane conductance regulator, is associated with reproductive, pancreatic, renal, intestinal and pulmonary disorders. Cystic fibrosis affects people of all races and ethnicities but is the most common life-limiting recessive genetic disorder affecting Caucasians.
Schultz has focused on cystic fibrosis at the molecular and cellular level for more than 30 years, including a 2019 sabbatical to a drug discovery and optimization laboratory at Rosalind Franklin University of the Health Sciences in North Chicago, Illinois. New techniques developed during the sabbatical form the foundation for the current seminar.