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K-State Today

November 7, 2023

Tarak Srivastava to present Biochemistry and Molecular Biophysics Seminar

Submitted by Biochemistry and Molecular Biophysics

Tarak Srivastava, professor of pediatric nephrology at the University of Missouri, Kansas City and Children's Mercy Hospital, will be the featured speaker for this week's Biochemistry and Molecular Biophysics Seminar. Srivastava will present "Hyperfiltration-mediated injury in progression of chronic kidney disease" at 4 p.m. Wednesday, Nov. 8, in 120 Ackert Hall.

Children born with congenital anomalies of the kidney and urinary tract, as well as adults with acquired chronic kidney disease, often inevitably progress to end-stage renal failure, necessitating dialysis and/or transplantation. One common modifiable mechanism influencing the progression of chronic kidney disease is injury mediated by hyperfiltration.

Srivastava will present his research, "Role of Biomechanical Forces in the Progression of Chronic Kidney Disease," which aims to comprehend the role of biomechanical forces on podocytes within the glomerulus to gain insight into the foundation of hyperfiltration-mediated injury. He will particularly focus on fluid flow shear stress in his presentation and discuss strategies to mitigate the progression of chronic kidney disease based on pre-clinical studies.

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