March 2, 2020
Tendai Gadzikwa to present Biochemistry and Molecular Biophysics seminar
Tendai Gadzikwa, professor of chemistry at Kansas State University, is the featured speaker for the upcoming Biochemistry and Molecular Biophysics seminar on Wednesday, March 4. She will present "Enzyme-Inspired Metal-Organic Framework (MOF) Materials" at 4 p.m. in 120 Ackert Hall.
Abstract: A long-standing goal in the field of supramolecular chemistry is the construction of catalysts that more adequately mimic the active sites of enzyme, i.e catalysts whose active sites are (i) confined, (ii) highly functionalized, and (iii) flexible. To this end, our group has introduced metal-organic framework, or MOF, materials as scaffolds on which we can deliberately organize complex chemical functionality within confined, 3-dimensional space. MOF materials are porous, crystalline solids with pores of small-molecule dimensions, and whose cavity environments are highly tailorable. While the pores of MOF materials can be decorated with a wide variety of chemical functionality, the ability to uniformly multifunctionalize MOF materials remains a challenge. This presentation will describe strategies we have developed for the construction of uniformly multifunctionalized MOF materials, and our progress toward the synthesis of enzyme-inspired catalytic materials.