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K-State Today

January 27, 2020

Brian Geisbrecht to present Anatomy and Physiology Seminar

Submitted by Gail L. Eyestone

Brian Geisbrecht, professor of biochemistry and molecular biophysics, will present "Immune Evasion of the Complement/Neutrophil Axis: a Biochemical Perspective" as part of the Anatomy and Physiology Seminar series. His presentation will be at 4 p.m. Tuesday, Jan. 28, in the Mara Conference Center, 407 Trotter Hall.

Geisbrecht focuses his research efforts upon understanding a recently identified series of Staphylococcal immune evasion proteins that act directly on key bactericidal enzyme systems found within the azurophilic granules of neutrophils. Work from his lab and others have shown that the bacterial pathogen Staphylococcus aureus secretes a collection of small proteins that have undergone exquisite optimization during the course of host/pathogen co-evolution to efficiently block central components of the human innate immune system.

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