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K-State Today

February 2, 2017

Bhaduri-McIntosh to discuss insights into cancer through Epstein-Barr virus seminar Feb. 3

By Sherry Fleming

Sumita Bhaduri-McIntosh, M.D. and Ph.D., from the School of Medicine and Cancer Center at Stony Brook University, will present a seminar at 4 p.m. Feb. 3 in 221 Ackert Hall. 

Bhaduri-McIntosh's research is focused on discovering fundamental biological pathways and understanding cancer development by studying the interaction between Epstein-Barr virus, or EBV — a cancer-causing virus —and its host, the B cell, by investigating two main areas:

1. Investigating how EBV subverts anti-pathogen and anti-cancer barriers such as immune responses and DNA-damage response (DDR)-induced cell-cycle checkpoints to drive B cell proliferation and transformation.

2. Identifying host factors that determine susceptibility of EBV-infected B cells to lytic activation, a process important for herpesvirus persistence in humans and for lymphomagenesis.