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Yang Lab

THE YANG LABORATORY
Division of Biology
Kansas State University
317 Ackert Hall (Office)
411 Ackert Hall (Lab)

Phone (lab): 785-532-6152
phone(office):785-532-3062
Email:zyang@ksu.edu 

Lab news

 

April 2021

Anil Pant, doctoral candidate in biology, Nepal, was awarded the $17,600 Alvin and RosaLee Sarachek Predoctoral Honors Fellowship in Molecular Biology. Congratulations, Dr. Pant!

March 2021

Congratulations to Anil for a successful dissertation defense! We look forward to your greater contibutions to science, Dr. Pant!

Candy Hernandez passed her prelim exam. Congrats to Ph.D. candidate Candy!

Congratulations to Lara for winning the 2nd place at K-State’s 2021 Three Minute Thesis competition. Great job, Lara!

January 2021

Our manuscript 'Viral Growth Factor and STAT3 Signaling-Dependent Elevation of the TCA Cycle Intermediate levels During Vaccinia Virus Infection' has been provisionally accepted for publication in PLOS Pathogens. Congratualtions to Anil, Lara, Shuai, and Chen!

November 2020

Congratulations to Josh Spradlin and Lake Winter for winning the Johnson Cancer Research Center Cancer Research Awards! 

August 2020

Our manuscript entitled "Poxvirus-encoded decapping enzymes promote selective translation of viral mRNAs" was accepted for publication in PLOS Pathogens. Congrats to Fred, Shuai, Candy, Pragyesh, and Josh Spradlin!

July 2020

Our Viewpoint manuscript "Asparagine: an Achilles Heel of Virus Replication?" was accepted for publication in ACS Infectious Diseases. Congrats to Anil! Keep it up!

Our manuscript "Identification of Vaccinia Virus Inhibitors and Cellular Functions Necessary for Efficient Viral Replication by Screening Bioactives and FDA-Approved Drugs" was accepted for publication in Vaccines (Basel). Congrats to Chen, Yannan, Shuai, Anil, Marlene, and our wonderful collaborators Peter and Anu.

Fred is moving to the Greater Boston area after three years in the Yang lab. We wish Fred the very best!

We're excited that Mark Gray joins the Yang lab as a Research Assistant! Welcome, Mark!

May 2020

Our review paper "Vaccinia Virus as a Master of Host Shutoff Induction: Targeting Processes of the Central Dogma and Beyond" was published in Pathogens. Congrats to Pragyesh, Fred, and Josh!

Anil Pant won the 2020 L. Evans Roth Award for Graduate Student Research in Cellular, Molecular or Developmental Biology. Congratulations to Anil! Keep up the good work!

April 2020

Congrats to Anil Pant for receiving the Sarachek Travel Award in molecular biology!

Congrats to Lake Winter for earning the Division of Biology Most Promising Student Award!

Congrats to Candy for winning Johnson Cancer Research Center Graduate Summer Stipend Award!

March 2020

Zhilong is promoted to associate professor with tenure. 

January 2020

We’re excited that Lara Dsouza joins the Yang Lab to complete her Ph.D. study! Welcome aboard, Lara!

December 2019

Zhilong recognized as Professor of The Week at the Dec. 7 K-State men's home basketball game.
https://www.k-state.edu/today/announcement/?id=59646

November 2019

Joshua Molina passed his preliminary exam. Congrats to Ph.D. candidate Josh!

October 2019

Josh Spradlin and Lake Winter won the Johnson Cancer Research Center's Cancer Research Awards (CRA). Congratulations, Josh and Lake!

September 2019

Our work was used as the example of success in Research, Scholarly and Creative Activities and Discovery during President Myers' 2019 State of the University address.

https://www.k-state.edu/facsen/sou/2019.html

August 2019

Congratulations to Josh Spradlin and Lake Winter for winning K-INBRE Undergraduate Research Scholar Awards!

July 2019

We receive an RO1 grant to study vaccinia virus protein synthesis. Many thanks to NIH for supporting our research by a group of dedicated scientists in the Yang lab at K-State!

June 2019

Congratulations to Pragyesh for being selected as Kansas State University’s nominee for the CGS/ProQuest Distinguished Dissertation Award in the Biological Sciences!

May 2019

Josh Molina joined the Yang lab. Josh is a Ph.D. student. Welcome, Josh!

April 2019

Congrats to Marlene for the Dean of Student Life Outstanding Graduating Senior Award and the Robinson Family Multicultural Leadership Award!

Pragyesh passed his Ph.D. defense. Congrats to Dr. Dhungel!

Anil Pant was selected to receive an American Society for Virology Travel Award to attend the 2019 ASV annual meeting in the Twin Cities, MN. Congrats to Anil!

Our manuscript "Asparagine is a critical limiting metabolite for vaccinia virus protein synthesis during glutamine deprivation" is accepted for publication in the Journal of Virology.  Congrats to Anil and Harry!

February 2019

Our manuscript "In vitro transcribed RNA-based luciferase reporter assay to study translation regulation in poxvirus-infected cells" is accepted for publication in JoVE.  Congrats to Pragyesh, Fred and Candy!

January 2019

Josh Spradlin and Hunter Rahor joined the Yang lab as undergraduate researchers. Welcome, Josh and Hunter!

Candy Hernandez joined the Yang lab to carry out her Ph.D. thesis research. Welcome, Candy!

September 2018

First BioRxiv deposit from the Yang Lab

Pant A, Cao S, Yang Z, Asparagine availability is an essential limiting factor for poxvirus protein synthesis, bioRxiv

August 2018

Congratulations to Yanan for a successful thesis defense for her Master's degree!

May 2018

Anil received the XXII International Poxvirus, Asfarvirus and Iridovirus Conference travel award, the Kansas State University Graduate Student Council travel award and the College of Arts and Sciences Travel grant to attend the poxvirus meeting 2018. Congrats!

Pragyesh received the XXII International Poxvirus, Asfarvirus and Iridovirus Conference travel award, the Kansas State University Graduate Student Council travel award and the College of Arts and Sciences Travel grant to attend the poxvirus meeting 2018. Congrats!

Pragyesh was awarded the 2018 Johnson Cancer research Center Graduate Student Summer Stipend. Congrats!

Shuai Cao was awarded the 2018 American Society for Virology Annual Meeting Travel Award and a Johnson Cancer Center travel award to attend the ASV meeting to be held in the University of Maryland-College Park, MD in July. Congrats!

Yanan Zhou won the 2018 American Society for Virology Annual Meeting Travel Award, the Kansas State University Graduate Student Council travel award and the College of Arts and Sciences Travel grant to attend the ASV meeting to be held in the University of Maryland-College Park, MD in July. Congrats!

April 2018

Pragyesh won the Alvin and RosaLee Sarachek Predoctoral Honors Fellowship and L. Evans Roth Award for Graduate Student Research in Cellular, Molecular or Developmental Biology. Congrats!

Our manuscript "Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff" was accepted for publication in Protein Cell.

November 2017

Members of Yang’s lab attended the 16th Annual Great Plains Infectious Disease Meeting (November 10 and 11th, 2017, Lawrence, KS). Pragyesh, Anil, Shuai, and Yanan each presented a poster. Zhilong gave a talk. 

Marlene was selected to receive a Johnson Cancer Center CRA award. Congrats!

 October 2017

Three manuscripts were accepted for publication recently

1. Cao S, Realegeno S, Pant A, Satheshkumar PS, Yang Z*. Suppression of poxvirus replication by resveratrol. Front Microbiol. Accepted.

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2. Dhungel P, Cao S, Yang Z*. The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation. PLoS Pathog. 2017 Aug 30;13(8):e1006602. 

Related: 
Checkmate: Researchers find mechanism that could improve therapies for cancer and infectious diseases

K-State researchers' finding could improve therapies for cancer, infectious diseases

3. Cao S, Dhungel P, Yang Z*. Going against the Tide: Selective Cellular Protein Synthesis during Virally Induced Host Shutoff. J Virol. 2017 Aug 10;91(17). pii: e00071-17. Review.

 September 2017

Fred Cantu Joined the lab as a Research Assistant! Welcome, Fred!

 July 2017

Chen Peng moved to Rockefeller University.  Best wishes to Chen!

 June 2017 

Four members of Yang’s lab attended the American Society for Virology Annual Meeting between June 24 and June 28 held in Madison, Wisconsin. Zhilong served as the convener of the Poxvirus II Workshop. Chen Peng and Pragyesh Dhungel each gave an oral presentation. Anil Pant presented a poster.

 April 2017

Chen's application of the K-INBRE postdoc award was approved. Congrats!

Anil was awarded the 2017 Johnson Cancer research Center Graduate Student Summer Stipend. Congrats!

Anil was awarded the 2017 American Society for Virology Annual Meeting Travel Award to attend the meeting to be held in Madison, WI in June. Congrats!

Alex Roeder received Dale H& Joan Evens Nordstorm Cancer Cancer Research Award (Johnson Cancer Research Center). Congrats!

Marlene received an honorable mention for the Most Promising Student in the Developing Scholar Program Annual Research Symposium. Congrats!

Yanan Zhou completed her rotation and joined the Yang Lab. Welcome!

Pragyesh passed his preliminary exam and is a Ph.D. candidate now. Congrats!

 March 2017

K-State today. 

Doctoral student's research on 'good' virus may one day help with treating bad diseases

February 2017

Anil won second place at Kansas State University's Three Minute Thesis competition finals. Congrats!
http://www.k-state.edu/media/newsreleases/2017-02/3mtwinners22117.html

 Three manuscripts were accepted for publication recently

1. Ribosome Profiling Reveals Translational Upregulation of Cellular Oxidative Phosphorylation mRNAs During Vaccinia Virus-induced Host Shutoff. J Virol

2. Enterovirus 71 3C Promotes Apoptosis through Cleavage of PinX1, a Telomere Binding Protein. J Virol

3. Anticancer Drug Camptothecin Test in 3D Hydrogel Networks with HeLa cells. Sci Rep

January 2017

Dalton Dacus and Yanan Zhou started their rotations in the Yang Lab. Welcome, Dalton and Yanan!

Yongquan Lin and Zhixun Zhao finished their one year visiting in the Yang Lab and went back to China. Best wishes to Yongquan and Zhixun!

August 2016

Marlene Campos Guerrero and Alex Roeder (Undergraduate students) joined the lab. Welcome, Marlene Campos and Alex!

July 2016

NIH award to establish research center on chemical biology of infectious disease. Zhilong Yang is a junior investigator of this newly established NIH Center for Biomedical Research Excellence. 

Chen Peng (Research Associate) joined the lab. Welcome, Chen!

June 2016

Pragyesh Dhungel presented a talk entitled "Translational Response to Vaccinia Virus Infection" in the 35th Annual Meeting for the American Society for Virology at the  Virginia Tech in Blacksburg, Virginia.

April 2016

Pragyesh Dhungel was awarded the Graduate Student travel grant to attend the 2016 American Society for Virology 35th annual meeting hosted by Virginia Tech, Blacksburg, June 18-22nd. He also won the K-state Graduate Student Council Travel Award to attend the meeting. Congratulations to Pragyesh! 

Pragyesh Dhungel was awarded the 2016 OIP Scholarship for International Students at Kansas State University. Congratulations to Pragyesh!

Anil Pant was awarded the 2016  Johnson Cancer research Center Graduate Student Summer Stipend. Congratulations to Anil!

Laura VanLerberg was awarded an undergraduate Student Cancer Research Award (Johnson Cancer Research Center). Congratulations to Laura!

Joshua May was awarded an undergraduate Student Cancer Research Award (Johnson Cancer Research Center). Congratulations to Josh!

Ana Simental was awarded an undergraduate Student Cancer Research Award (Johnson Cancer Research Center). Congratulations to Ana!

February 2016

Our paper "Molluscum Contagiosum Virus Transcriptome in Abortively Infected Cultured Cells and Human Skin Lesion" was accepted for publication in Journal of Virology

http://jvi.asm.org/content/early/2016/02/11/JVI.02911-15.abstract

January 2016

Zhixun Zhao and Yongquan Lin (Visiting Scholars) joined the lab. Welcome, Zhixun and Yongquan!

September 2015

1.  Our paper "Decoding Poxvirus Genome" was accepted for publication in Oncotarget: Microbiology and Immunology.

http://www.ncbi.nlm.nih.gov/pubmed/26429864

2. Our paper "RPFdb: a database for genome-wide information of translated mRNA generated from ribosome profiling." was accepted for publication in Nucleic Acids Research.

http://www.ncbi.nlm.nih.gov/pubmed/26433228

 August 2015

Anil Pant (Ph.D. student) joins the Yang Lab. Welcome!

Dalton Dacus receives KSU Arts & Sciences Undergraduate Research Award. Congrats!

Laura VanLerberg receives KSU Arts & Sciences Undergraduate Research Award for Fall 2015. Congrats!

May 2015

Canaan Coker receives the H.H. Haymaker Outstanding Senior Award of Biology. Congrats!

Canaan

April 2015
Our paper "Deciphering Poxvirus Gene Expression by RNA Sequencing and Ribosome Profiling" is accepted for publication in Journal of Virology.

Pragyesh Dhundel receives the award for Graduate Student Summer Stipends from the Johnson Center for Basic Cancer Research. Congrats!

Lab website launches!