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Department of Biochemistry and Molecular Biophysics

Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
1711 Claflin Rd.
Manhattan, KS 66506
785-532-7278 fax

Biotechnology Core Facility
206 Burt Hall
785-532-6297 fax

Biomolecular NMR Facility
37 Chalmers Hall

John Tomich, Ph.D., Professor
Director of Biotechnology/Proteomics Core Facility
Undergraduate Advisor

Image of John Tomich, Ph.D.Image of Dr. Tomich with student and link to Dr. Tomich's YouTube research video

Research Video

Contact information

Office: 206 Burt Hall
Phone: 785-532-5956
Fax: 785-532-6297
E-mail: jtomich@ksu.edu
Lab website


B.A. 1974, University of Connecticut
M.S. 1975, Purdue University
Ph.D. 1980, University of Waterloo

Areas of specialty

The Tomich laboratory designs and characterizes synthetic peptides for potential uses as drugs or renewable biomaterials. The lab employs a number of biologic, synthetic, analytic and physical methods to make these characterizations.

Read detailed research description

Selected publications

Natarajan, P., Tomich, J. M. Bio-Interactions of Gold and Iron Oxide Nanoparticles : The Role of Experimental Parameters on in vitro and in vivo Interactions Arch. Biochem. Biophys. (2020) 694,108592 doi:10.1016/j.abb.2020.108592.

Natarajan, P., Roberts, J., Kunte, N., Hunter, W. B., Fleming, S., Tomich, J. M., Avila, L. A. (2020) Cellular Uptake Mechanisms Of Branched Amphiphilic Peptide Capsules Probed with Hollow Water Filled and Magnetic Core Nanospheres. Mol Pharm. 2020 17(6) 2208–2220 doi:10.1021/acs.molpharmaceut.0c00393. PMID:32324415

Wessel, E. M., Tomich, J. M., Todd, R. B. Biodegradable Drug-Delivery Peptide Nano-Capsules ACS-Omega 2019 4, 22, 20059–20063. doi:10.1021/acsomega.9b03245. PMID:31788640

Hunter, W. B., Gonzalez, M. T., Tomich, J. M. (2018) BAPC-assisted CRISPR/Cas9 System: Targeted Delivery into Adult Ovaries for Heritable Germline Gene Editing (Arthropoda: Hemiptera) bioRxiv 478743; doi:10.1101/478743

Avila, L.A., Chandrasekar, R., Wilkinson, K. E. Balthazor, J., Herman, M., Bechard, J., Brown, S., Park, Y., Dhar, S., Reeck, G.R., Tomich, J. M. Delivery of lethal dsRNAs in insect diets by Branched Amphiphilic Peptide Capsules. J. Control Release (2018) 273, 139-146. doi: 10.1016/j.jconrel.2018.01.010. PMID:29407675

Barros, S. M., Avila, L. A., Whitaker, S. K., Sukthankar, P., Beltrão, E. I. C., Tomich, J. M. (2017) Branched Amphipathic Peptide Capsules: Different Ratios of the Two Constituent Peptides Direct Distinct Bilayer Structures and Sizes. Langmuir. 33(28):7096-7104. doi: 10.1021/acs.langmuir.7b00912. PMID:28654272

Barros, S. M., Whitaker, S. K., Sukthankar, P. R., Gudlur, S., Warner, M. Beltrão, E. I. C., Tomich, J.M. (2016) A Review of Solute Encapsulating Nanoparticles used as Delivery Systems with Emphasis on Branched Amphipathic Peptide CapsulesArch Biochem Biophys. 596: 22-42. PMID: 26926258

Sukthankar, P, Whitaker, S.K., Garcia, M., Herrera, A., Boatwright, M., Prakash, O., and Tomich, J.M. (2015) Thermally Induced Conformational Transitions in Nascent Branched Amphiphilic Peptide Capsules.  Langmuir. 2015 Mar 17;31(10):2946-55. doi: 10.1021/la504381y. Epub 2015 Mar 6. PMID: 2571959

Avila, L.A., Aps, L. R. M. M., Sukthankar, P., Ploscariu, N., Gudlur, G., Šimo,L. Szoszkiewicz, R., Park, Y., Lee, S. W., Iwamoto, T., Ferreira, L.,  Tomich, J. M. (2015) Alternate supramolecular structures for different ratios of branched amphiphilic cationic peptide /DNA assemblies: Correlation with gene deliveryMol Pharm. 12(3):706-15. PMID: 25647162

Sukthankar, P., Avila, LA., Whitaker, SK., Iwamoto, T., Morgenstern, A., Apostolidis, C., Liu, K., Hanzlik, RP., Dadachova, E., and Tomich, JM. (2014) Branched Amphiphilic Peptide Capsules: Cellular Uptake and Retention of Encapsulated Solutes. Biochim, Biophys. Acta, Biomembranes 1838: 2296-2305. PMID: 24565797.

Chen, J., and Tomich, JM. (2014) Free Energy Analysis of Conductivity and Charge Selectivity of M2GlyR-Derived Synthetic Channels. Biochim, Biophys. Acta, Biomembranes 2014 Sep; 1838 (9):2319-25. PMID: 24582709.

Sukthankar, P., Gudlur, S., Avila, L.A., Whitaker, S., Katz, B.B., Hiromasa, Y., Gao, J., Thapa, P., Moore, D., Iwamoto, T., Tomich, J.M. (2013) Branched Oligopeptides Form Nano-Capsules with Lipid Vesicle CharacteristicsLangmuir 29:14648−14654. PMC3889211

Gudlur, S., Sukthankar, P., Gao, J. Avila, L.A., Hiromasa, Y., Chen, J., Iwamoto, T., Tomich, J.M. (2012) Peptide Nanovesicles Formed by the Self-Assembly of Branched Amphiphilic Peptides. PLOS ONE. 7 (9) e45374 pages 1-11 PMC3445502

Complete Publications List