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K-State Today

March 18, 2021

Philip R. Hardwidge to present Diagnostic Medicine/Pathobiology Seminar

Submitted by Brandy Nowakowski

Philip R. Hardwidge, professor and associate director of NIH COBRE Center on Emerging and Zoonotic Infectious Diseases at K-State, will present "A New Domain for Old Proteins: Injected T3SS Effectors Also Function Within the Bacterium" at 3:30 p.m. Thursday, March 18, via Zoom.

Hardwidge received his doctorate from the Mayo Clinic Graduate School and completed a postdoctoral fellowship at the University of British Columbia.

Currently a professor of diagnostic medicine and pathobiology, Hardwidge leads a research program focused on understanding, treating and preventing diarrheal disease caused by bacterial pathogens — e.g. E. coli O157:H7, non-O157 STEC, and ETEC — that affect both humans and livestock. These pathogens represent important threats to food safety, biosecurity and animal health. In many cases, vaccines are not available or are ineffective, and the basic molecular microbiology of the host-pathogen interaction is relatively poorly understood. Hardwidge's research team has discovered several mechanisms by which bacterial proteins subvert the host innate immune system to promote bacterial colonization and transmission. Hardwidge’s research program has been continuously funded by the NIH since 2006.