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Department of Biochemistry and Molecular Biophysics

Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
1711 Claflin Rd.
Manhattan, KS 66506
785-532-6121
785-532-7278 fax
biochem@k-state.edu

Biotechnology Core Facility
206 Burt Hall
785-532-5956
785-532-6297 fax

Biomolecular NMR Facility
37 Chalmers Hall
785-532-2345

John Tomich, Ph.D., Professor
Director of Biotechnology/Proteomics Core Facility
Undergraduate Advisor

Image of John Tomich, Ph.D.Image of Dr. Tomich with student and link to Dr. Tomich's YouTube research video

Research Video

Contact information

Office: 206 Burt Hall
Phone: 785-532-5956
Fax: 785-532-6297
E-mail: jtomich@ksu.edu
Lab website

Education

B.A. 1974, University of Connecticut
M.S. 1975, Purdue University
Ph.D. 1980, University of Waterloo

Areas of specialty

The Tomich laboratory designs and characterizes synthetic peptides for potential uses as drugs or renewable biomaterials. The lab employs a number of biologic, synthetic, analytic and physical methods to make these characterizations.

Read detailed research description

Selected publications

Herrera, A.I., Tomich, J.M., Prakash O. (2016) Membrane Interacting Peptides: A Review. Current Protein & Peptide Science In press.

Barros, S. M., Whitaker, S. K., Sukthankar, P. R., Gudlur, S., Warner, M. Beltrão, E. I. C., Tomich, J.M. (2016) A Review of  Solute Encapsulating Nanoparticles used as Delivery Systems with Emphasis on Branched Amphipathic Peptide CapsulesArch Biochem Biophys. 596: 22-42. PMID: 26926258

Sukthankar, P, Whitaker, S.K., Garcia, M., Herrera, A., Boatwright, M., Prakash, O., and Tomich, J.M. (2015) Thermally Induced Conformational Transitions in Nascent Branched Amphiphilic Peptide Capsules.  Langmuir. 2015 Mar 17;31(10):2946-55. doi: 10.1021/la504381y. Epub 2015 Mar 6. PMID: 2571959

Avila, L.A., Aps, L. R. M. M., Sukthankar, P., Ploscariu, N., Gudlur, G., Šimo,L. Szoszkiewicz, R., Park, Y., Lee, S. W., Iwamoto, T., Ferreira, L.,  Tomich, J. M. (2015) Alternate supramolecular structures for different ratios of branched amphiphilic cationic peptide /DNA assemblies: Correlation with gene deliveryMol Pharm. 12(3):706-15. PMID: 25647162

Avila, L.A, Lee, S. and Tomich J.M. (2014) “Synthetic in vitro delivery systems for plasmid DNA in eukaryotes” (review) J. Nanopharmaceutics and Drug Delivery 2: 17-35.

Sukthankar, P., Avila, LA., Whitaker, SK., Iwamoto, T., Morgenstern, A., Apostolidis, C., Liu, K., Hanzlik, RP., Dadachova, E., and Tomich, JM. (2014) Branched Amphiphilic Peptide Capsules: Cellular Uptake and Retention of Encapsulated Solutes. Biochim, Biophys. Acta, Biomembranes 1838: 2296-2305. PMID: 24565797.

Chen, J., and Tomich, JM. (2014) Free Energy Analysis of Conductivity and Charge Selectivity of M2GlyR-Derived Synthetic Channels. Biochim, Biophys. Acta, Biomembranes 2014 Sep; 1838 (9):2319-25. PMID: 24582709.

Sukthankar, P., Gudlur, S., Avila, L.A., Whitaker, S., Katz, B.B., Hiromasa, Y., Gao, J., Thapa, P., Moore, D., Iwamoto, T., Tomich, J.M. (2013) Branched Oligopeptides Form Nano-Capsules with Lipid Vesicle CharacteristicsLangmuir 29:14648−14654. PMC3889211

Gudlur, S., Sukthankar, P., Gao, J. Avila, L.A., Hiromasa, Y., Chen, J., Iwamoto, T., Tomich, J.M. (2012) Peptide Nanovesicles Formed by the Self-Assembly of Branched Amphiphilic Peptides. PLOS ONE. 7 (9) e45374 pages 1-11 PMC3445502

View complete publications list