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Department of Biochemistry and Molecular Biophysics

Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
1711 Claflin Rd.
Manhattan, KS 66506
785-532-7278 fax

Biotechnology Core Facility
206 Burt Hall
785-532-6297 fax

Biomolecular NMR Facility
37 Chalmers Hall

John Tomich, Ph.D., Professor
Director of Biotechnology/Proteomics Core Facility
Undergraduate Advisor

Image of John Tomich, Ph.D.Image of Dr. Tomich with student and link to Dr. Tomich's YouTube research video

Research Video

Contact information

Office: 206 Burt Hall
Phone: 785-532-5956
Fax: 785-532-6297
E-mail: jtomich@ksu.edu
Lab website


B.A. 1974, University of Connecticut
M.S. 1975, Purdue University
Ph.D. 1980, University of Waterloo

Areas of specialty

The Tomich laboratory designs and characterizes synthetic peptides for potential uses as drugs or renewable biomaterials. The lab employs a number of biologic, synthetic, analytic and physical methods to make these characterizations.

Read detailed research description

Selected publications

Tomich, JM., Bukovnik, U., Layman JS., and Schultz BD. (2012) Channel Replacement Therapy for Cystic Fibrosis in "Cystic Fibrosis", InTech - Open Access Publisher ISBN 979-953-307-059-8.

Bukovnik, U., Gao, J., Cook, GA., Shank, LP., Seabra, MB., Schultz, BD., Iwamoto, T., Chen, J., and Tomich, JM. (2011) Structural and biophysical properties of a synthetic channel-forming peptide: designing a clinically relevant anion selective pore. Biochim, Biophys. Acta Jul 31. [Epub ahead of print]. PMID: 21835162

Herrera, AI., Al-Rawi, A., Cook GA., Prakash, O., Tomich, JM., and Chen, J. (2010) Structural characterization of two pore-forming eptide: consequences of introducing a C-terminal tryptophan.  PROTEINS: Structure, Function, and Genetics 78(10):2238-2250. PMC2909830

Martin, J., Devlin, S., Malreddy, P., Iwamoto, T., Freeman, L., Davidson, H., Tomich, JM., and Schultz, BD. (2009) NC-1059, NC-1059 A Channel-Forming Peptide Modulates Drug Delivery Across In Vitro Corneal Epithelium.  Invest. Ophthal. Vis. Sci. 50(7):3337-3345. PMID: 19234338

Somasekharan, S., Brandt, R., Iwamoto, T., Tomich, JM., and Schultz, BD. (2008) Epithelial barrier modulation by a forming Peptide.  J. Membr. Biol. 222:17-30. PMID: 18418541

van Ginkel, FW., Iwamoto, T., Schultz, BD., and Tomich, JM. (2008) Immunity to Self-derived, Anion Channel-Forming Peptides in the Respiratory Tract.  Clinical and Vaccine Immunology 15(2):260-266. PMID: 18094111

Mo, X., Hiromasa, Y., Al-Rawi, A., Warner, M., Iwamoto, T., Rahman, T., Sun, X., and Tomich, JM. (2008) Design of 11-Residue Peptides with Unusual Biophysical Properties: Induced Secondary Structure in the Absence of Water.  Biophysical J. 94:1807-1817. PMID: 18024497

Johnston, JM., Cook, GA., Tomich, JM., and Sansom, MS. (2006) Conformation And Environment Of Channel Forming Peptides: A Simulation Study.  Biophys J. 90:1855-1864.

View complete publications list