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College of Veterinary Medicine Core Facilities




Bhattarai R, Dhital S, Mense A, Gidley M, Shi YC (2018). Intact cellular structure in cereal endosperm limits starch digestion in vitro. Food Hydrocolloids 81, 139-148.  PMID: ?  PMCID: ?

Paper JM, Mukherjee T, Schrick K (2018) Bioorthogonal click chemistry for fluorescence imaging of choline phospholipids in plants. Plant Methods 14:31.  PMID: 29692861  PMCID: PMC5905148.

Pitchaimani A, Nguyen TDT, Aryal S (2018) Natural killer cell membrane infused biomimetic liposomes for targeted tumor therapy. Biomaterials 160:124-137. PMID: 29407341 PMCID: ?

Guo R, Davis RD, Fang Y (2018) Intercellular transfer of mitochondria rescues virus-induced cell death but facilitates cell-to-cell spreading of porcine reproductive and respiratory syndrome virus. Virology 517:122-134 PMID: 29307597 PMCID: ?

Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee YJ, Grima JC, Mao X, Jiang H, Kang SU, Swing D, Iacovitti L, Tessarollo L, Dawson TM, Dawson VL (2018) Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Proc Natl Acad Sci USA 115:1635-1640 PMID: 29386392  PMCID: PMC5816154.

Basel MT, Narayanan S, Ganta CK, Shreshta TB, Marquez A, Pyle M, Hill J, Bossmann SH, Troyer DL (2018) Developing a xenograft human tumor model in immunocompetent mice. Cancer Lett 412:256-263. PMID: 29054784.  PMCID: ?


Guo R, Davis D, Fang Y (2017). Intercellular transfer of mitochondria rescues virus-induced cell death but facilitates cell-to-cell spreading of porcine reproductive and respiratory syndrome virus. Virology 517: 122-134. PMID: 29307597.

Aryal S, Nguyen, TDT, Pitchaimani A, Shrestha TB, Biller D, Troyer D (2017) Membrane Fusion-Mediated Gold Nanoplating of Red Blood Cell: A Bioengineered CT-Contrast Agent.  ACS Biomater Sci Eng 3: 36-41. PMID: ?

Reeves WM, Wu Y, Harder MJ, Veeman MT (2017). Functional and evolutionary insights from the Ciona notochord transcriptome. Development 144: 3375-3387. PMID: 28928284. PMCID: PMC5612257.

Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ (2017) Molecular architecture underlying fluid absorption by the developing inner ear.  eLife 6: e26851.  PMID: 28994389.  PMCID: PMC5634787.

Vu TH, Bean S, Hsieh CF, Shi YC (2017). Changes in protein and starch digestibility in sorghum flour during heat-moisture treatments. J Sci Food Agric 97:4770-4779. PMID: 28369903.  PMCID:

Silver K, Littlejohn A, Thomas L, Bawa B, Lillich JD (2017) Suppression of Calpain Expression by NSAIDs is Associated with Inhibition of Cell Migration in Rat Duodenum. Toxicology 383: 1-12. PMID: 28342779.  PMCID: PMC5519291.

Mills MK, Nayduch D, McVey DS, Michel K (2017). Functional validation of apoptosis genes IAP1 and DRONC in midgut tissue of the biting midge Culicoides sonorensis by RNAi. J Med Entomol 54:559-567 PMID: 28399198.  PMCID: PMC5502902.

Kim MJ, Park SC, Choi KS (2017). Dual-nozzle spray deposition process for improving the stability of proteins in polymer microneedles. RSC Advances 7, 55350

Nguyen TDT, Pitchaimani A, Ferrel C, Thakkar R, Aryal S (2017) Nano-confinement-driven enhanced magnetic relaxivity of SPIONs for targeted tumor bioimaging. Nanoscale 10:284-294. PMID: 29210434


Goering J, Pope MR, Fleming SD (2016). TLR2 regulates complement-mediated inflammation induced by blood loss during hemorrhage. Shock 45:33-9 PMCID: PMC4685733.

Kozel C, Thompson B, Hustak S, Moore C, Nakashima A, Singh CR, Reid M, Cox C, Papadopoulos E, Luna RE, Anderson A, Tagami H, Hiraishi H, Slone EA, Yoshino KI, Asano M, Gillaspie S, Nietfeld J, Perchellet JP, Rothenburg S, Masai H, Wagner G, Beeser A, Kikkawa U, Fleming SD, Asano K (2016). Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and induces ATF4 translation through delayed re-initiation. Nucleic Acids Res 44: 8704-871. PMCID: PMC5062967

Ishiguro S, Cai S, Uppalapati D, Turner K, Zhang T, Forrest CW, Forrest MF, Tamura T (2016). Intratracheal administration of hyaluronan-cisplatin conjugate nanoparticle significantly attenuates lung cancer growth in mice. Pharm Res 33: 2517-29 PMID: 27335023.  PMCID: 5007205.

Ishiguro S, Alhakamy NA, Uppalapati D, Delzeit J, Berkland C, Tamura M (2016). A combination delivery with an intravenous injection and an intratracheal aerosol spray of AT2R gene by modified TAT peptide nanoparticles attenuates human bronchioloalveolar carcinoma xenografts in immunodeficient mice. J Pharm Sci 106: 385-394.  PMID: 27769520. PMCID: PMC5161536.

Zhang X, An CJ, Sprigg KJ, and Michel K (2016). CLIPB8 is part of the prophenoloxidase activation system in Anopheles gambiae mosquitoes. Insect Biochem Mol Biol. 71: 106–115 PMID: 26926112 PMCID: PMC4828722.

Krishnamoorthy G, Reimann K, Wangemann P (2016) Ryanodine-induced vasoconstriction of the gerbil spiral modiolar artery depends on the Ca2+ sensitivity but not on Ca2+ sparks or BK channels. BMC Physiol 16:6  PMCID: 5093982 

Pitchaimani A, Nguyen TD, Wang H, Bossmann SH, Aryal S (2016). Design and characterization of gadolinium infused theranostic liposomes. RSC Adv 6: 36898-36905. PMCID: ?

Nguyen TD, Pitchaimani A, Koirala MB, Muhammad F, Aryal S (2016). Engineered biomimetic nanoabsorbent for cellular detoxification of chemotherapeutics. RSC Adv 6: 33003-33008.  PMCID: ?

Nguyen TD, Pitchaimani A, Aryal S (2016). Engineered Nanomedicine with Alendronic Acid Corona Improves Targeting to Osteosarcoma. Scientific Reports 6:36707 PMID: 27824143

Guo R, Katz BB, Tomich JM, Gallagher T, Fang Y (2016). Porcine Reproductive and Respiratory Syndrome Virus Utilizes Nanotubes for Intercellular Spread. J Virol. 90:5163-75. PMID: 26984724 PMCID: PMC4859731

Bryant WB, Michel K (2016). Anopheles gambiae hemocytes exhibit transient states of activation. Dev Comp Immunol. 55: 119-29 PMID: 26515540 PMCID: PMC4685016


Slone EA, Pope MR, Fleming SD (2015). Phospholipid scramblase 1 is required for β2-glycoprotein I binding in hypoxia and reoxygenation-induced endothelial inflammation. J Leukoc Biol 98: 791-804 PMID: 26216936 PMCID: PMC4600063

Silver K, Littlejohn A, Thomas L, Marsh E, Lillich JD (2015). Inhibition of Kv channel expression by NSAIDs depolarizes membrane potential and inhibits cell migration  by disrupting calpain signaling. Biochemical Pharmacology 98: 614-628. PMID: 26549367 PMCID: PMC4656099

Heerman M, Weng JL, Hurwitz I, Durvasula R, Ramalho-Ortigao M (2015). Bacterial Infection and Immune Responses in Lutzomyia longipalpis Sand Fly Larvae Midgut. PLoS Negl Trop Dis 9: e0003923. PMID: 26154607 PMCID: PMC4495979

Pierucci-Alves F, Akoyev V, Schultz BD (2015). Bicarbonate exchangers SLC26A3 and SLC26A6 are localized at the apical membrane of porcine vas deferens epithelium. Physiol Rep 3: e12380. PMID:25907791

Veeman M, Reeves W (2015). Quantitative and in toto imaging in ascidians: working toward an image-centric systems biology of chordate morphogenesis. Genesis 53:143-59. PMID: 25262824 PMCID: PMC4378666

Carlson M, Reeves W, Veeman M (2015). Stochasticity and stereotypy in the Ciona notochord. Developmental Biology 397:248-56. PMID: 25459659

Pope MR, Fleming SD (2014). TLR2 modulates antibodies required for intestinal ischemia/reperfusion-induced damage and inflammation. J Immunol 194: 1190-8. PMID: 25539820 PMCID: PMC4297697


Agrawal, S., Kelkenberg, M., Begum, K., Lea, S., Williams, C. E., Kramer, K. J., Park, Y., Muthukrishnann, S., Merzendorfer, M.  (2014) Two essential peritrophic matrix proteins mediate matrix barrier functions in the insect midgut. Insect Biochemistry and Molecular Biology 49: 24-34. PMID: 24680676

Bigelow K, Nguyen TA (2014). Increase of gap junction activities in SW480 human colorectal cancer cells. BMC Cancer 14: 502. PMID: 25008544 PMCID: PMC4226976

Bryant WB, Michel K. Blood feeding induces hemocyte proliferation and activation in the African malaria mosquito, Anopheles gambiae Giles. J Exp Biol 217:1238-45. PubMed PMID: 24363411; PMCID: PMC3990356.

Chaudhari, S. S., Moussian, B., Specht, C.A., Arakane, Y., Kramer, K.J., Beeman, R.W., Muthukrishnan, S. (2014). Functional specialization among members of Knickkopf family of proteins in insect cuticle organization. PloS Genet 10: e1004537 PMID: 25144557 PMCID: PMC4140639

Dib LH, Ortega MT, Fleming SD, Chapes SK, Melgarejo TL (2014). Bone Marrow Leptin Signaling Mediates Obesity-Associated Adipose Tissue Inflammation in Male Mice. Endocrinology 155: 40-46. PMID: 24169547 PMCID: PMC3868799

Kim KX, Sanneman JD, Kim HK, Harbidge DG, Xu J, Soleimani M, Wangemann P, Marcus DC (2014). Slc26a7 chloride channel activity and localization in mouse Reissner’s membrane epithelium. PLoS ONE 10: e97191. PMID: 24810589 PMCID: PMC4014619

Mao X, Zhang Y, Schwend T, Conrad GW (2014). Effects of polysialic acid on sensory innervation of the cornea. Dev Biol 398: 193-205. PMID:25478909 PMCID:PMC3868799

Montero-Astúa M, Rotenberg D, Leach A, Schneweis B, Park K, Park SH, German TL, Whitfield AE (2014). Disruption of vector transmission by a plant-expressed viral glycoprotein. Molecular Plant-Microbe Interactions 27:296-304. PMID: 24405031

Reeves W, Thayer R, Veeman V (2014). Anterior-posterior regionalized gene expression in the Ciona notochord. Dev Dyn. 243: 612-20. PMID: 24288133 PMCID: PMC4060897

Smallwood CR, Jordan L, Trinh V, Schuerch DW, Gala A, Hanson M, Shipelskiy Y, Majumdar A, Newton SM, Klebba PE. (2014). Concerted loop motion triggers induced fit of FepA to ferric enterobactin. J Gen Physiol 44:71-80. PMID: 24981231 PMCID: PMC4076525

Veeman M, Reeves W (2014). Quantitative and in toto imaging in ascidians: working towards an image-centric systems biology of chordate morphogenesis. Genesis 53: 143-59. PMID: 25262824 PMCID: PMC4378666

Wang Q, Schultz BD (2014). Cholera toxin enhances Na+ absorption across MCF10A human mammary epithelia.  Am J Physiol Cell Physiol 306: C471-84. PMID: 24371040 PMCID: PMC4042620

Xie L, Fu Q, Ortega MT, Zhou L, Rasmussen D, O'Keefe J, Zhang KK, Chapes SK (2014). Overexpression of IL-10 in C2D macrophages promotes a macrophage phenotypic switch in adipose tissue environments. PloS ONE 9: e86541. PMID 24466141 PMCID: PMC3897709


Ding Y, Nguyen TA (2013) PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9.  Apoptosis 18:1071-82.  PMID: 23677255

Huang H, Ding Y, Sun XS, Nguyen TA (2013) Peptide hydrogelation and cell encapsulation for 3D culture of MCF-7 breast cancer cells.  PLoS One. 8: e59482.  PMID: 23527204

Yi S, Pierucci-Alves F, Schultz BD. (2013) Transforming growth factor-β1 impairs CFTR-mediated anion secretion across cultured porcine vas deferens epithelial monolayer via the p38 MAPK pathway.  Am J Physiol Cell Physiol.  305:C867-76.  PMID: 23903699

Kawabata A, Ohta N, Seiler G, Pyle MM, Ishiguro S, Zhang YQ, Becker KG, Troyer D, Tamura M (2013) Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses.  Cytotherapy. 15:586-97. PMID: 23474329

Ohta N, Kawabata A, Uppalapati D, Ishiguro S, Troyer D, Tamura M. (2013) Cytotherapy for breast cancer by umbilical cord matrix stem cells.  IN: Stem Cell Therapeutics for Cancer, Editor: Shah K, Wiley publisher, pp111-126, Print ISBN: 9781118282427, Online ISBN: 9781118660423

Reimann K, Krishnamoorthy G, Wangemann P (2013) NOS inhibition enhances myogenic tone by increasing rho-kinase mediated Ca2+ sensitivity in the male but not the female gerbil spiral modiolar artery.  PLoS One e53655.  PMID: 23301097

Li X, Zhou F, Marcus DC, Wangemann P (2013) Endolymphatic Na+  and K+  concentrations during cochlear growth and enlargement in mice lacking Slc26a4/pendrin.  PLoS One 8: e65977.  PMID: 23741519

Li X, Sanneman JD, Harbidge DG, Zhou F, Ito T, Nelson R, Picard N, Chambrey R, Eladari D, Miesner T, Griffith AJ, Marcus DC, Wangemann P. (2013) SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice.  PLoS Genet 9: e1003641. PMID: 23874234

Chaudhari SS, Arakane Y, Specht CA, Moussian B, Kramer KK, Muthukrishnan S,  Beeman RW (2013) Retroactive maintains cuticle integrity by promoting the trafficking of Knickkopf into the procuticle of Tribolium castaneum.  PLoS Genet. 9:e1003268  PMID: 23382702

Giraldo MC, Dagdas YF, Gupta YK, Mentlak TA, Yi M, Martinez-Rocha AL, Saitoh H, Terauchi R, Talbot NJ, Valent B (2013) Two distinct secretion systems facilitate tissue invasion by the rice blast fungus Magnaporthe oryzae. Nature Communications. Article number: 4:1996. PMID: 23774898

Giraldo MC, Valent B (2013) Filamentous plant pathogen effectors in action. Nature Reviews Microbiology. 11:800–814. PMID: 24129511

Gregory C, Veeman M (2013) 3D-printed microwell arrays for Ciona microinjection and timelapse imaging. PLoS ONE. 8:e82307.  PMID: 24324769

Reeves W, Thayer R, Veeman M (2013) Anterior-posterior regionalized gene expression in the Ciona notochord. Dev Dyn. 243:612-20 PMID: 24288133

Hu Y, Zhang J, Jia H, Sosso D, Lie T, Frommer W, Yang B, White FF, Wang N, Jones J (2013) Lateral organ boundaries 1 is a disease susceptibility gene for citrus bacterial canker disease. Proc Natl Acad Sci. 11:E521-9. PMID: 24474801


Basel MT, Balivada S, Wang H, Shrestha TB, Seo GM, Pyle M, Abayaweera G, Dani R, Koper OB, Tamura M, Chikan V, Bossmann SH, Troyer DL (2012). Cell-delivered magnetic nanoparticles caused hyperthermia-mediated increased survival in a murine pancreatic cancer model. Int J Nanomedicine 7:297-306. PMID: 22287840 PMCID: PMC3265998

Basel MT, Balivada S, Shrestha TB, Seo GM, Pyle MM, Tamura M, Bossmann SH, Troyer DL (2012). A cell-delivered and cell-activated SN38-dextran prodrug increases survival in a murine disseminated pancreatic cancer model. Small 8:913-20. PMID: 22238072 PMCID: PMC3583224

Pope M, Bukovnik U, Tomich JM, Fleming SD (2012). Small β2-glycoprotein I peptides protect from intestinal ischemia reperfusion injury. J Immunol 189: 5047–5056. PMID: 23034168 PMCID: PMC3489961

Slone E, Pope M, Roth M, Welti R, Fleming SD (2012). TLR9 is dispensable for intestinal ischemia/reperfusion-induced tissue damage. Am J Clin Exp Immunol. 1: 124–135. PMID: 23205322 PMCID: PMC3509382

Tomasi M, Hiromasa Y, Pope M, Gudlur S, Tomich JM, Fleming SD (2012). Human β2-glycoprotein I attenuates mouse intestinal ischemia/reperfusion induced injury and inflammation. Mol Immunol 52: 207–216. PMID: 22750067 PMCID: PMC3565431

Schwend T, Deaton RJ, Zhang Y, Caterson B, Conrad GW. (2012) Corneal sulfated glycosaminoglycans and their effects on trigeminal nerve growth cone behavior in vitro: roles for ECM in cornea innervation. Invest Ophthalmol Vis Sci 53: 8118-37.  PMID: 23132805

Zhang Y, Sukthankar P, Tomich JM, Conrad GW (2012) Effect of the synthetic NC-1059 peptide on diffusion of riboflavin across an intact corneal epithelium. Invest Ophthalmol Vis Sci. 53: 2620-9. PMID: 22447859