Reference Number: 04-03
Inventor: Duy Hua
Description:
K-State has found recent success in the synthesis of new zinc chelators, bishydroxamic acids, for the development of new antiviral drugs. Removal of zinc ions from zinc-fingers viral proteins or viral RNA polymerases leads to the inhibition of viral replication. These zinc-finger motifs have been found in HIV-1 and the existence of similar motifs have been found among other viruses such as polio, human coxsackie, SARS, rabies, human parainfluenza, measles, human respiratory syncytial, human hepatitis, Dengue, West Nile and Ebola.
These zinc chelators could potentially lead to safe and less expensive antiviral drugs.
Patent Status
Kansas State University Research Foundation seeks to have discussions with companies that are interested in licensing and/or research collaborations.
Interested parties should contact:
National Institute for Strategic Technology Acquisition and
Commercialization (NISTAC)
2005 Research Park Circle Manhattan, KS 66502
Tel: 785-532-3900 Fax: 785-532-3909
E-Mail: nistac@ksu.edu