News

BIOPHYSICAL SOCIETY 2025

Dr. Fong and Dr. Pusch presented their latest collaborative work at the 69th Annual Meeting of the Biophysical Society, held in beautiful Los Angeles, CA!

NOTICE OF AWARD: May 24, 2023

Our collaborative work with the Pusch lab to study ClC-6 and ClC-7 function in endo-lysosomes is now funded via an R21 award from National Institutes of Neurological Disorders and Stroke.

NEW PUBLICATIONS!

Distinct ClC-6 and ClC-7 Cl^- sensitivities provide insight into ClC-7’s role in lysosomal Cl^- homeostasis, by Maria Antonietta Coppola et al, is the latest collaborative study with Michael Pusch's group in the Institute of Biophysics, Genoa, Italy . The graphical abstract* below summarizes the basic findings published in the December 15th, 2023 issue of The Journal of Physiology.

*Graphical abstract credit: Created with BioRender.com.

You can read the paper by following the link below!

https://physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP285431

This study built on findings of an earlier study, Altered voltage-dependence of slowly activating chloride-proton antiport by late endosomal ClC-6 explains distinct neurological disorders, performed in collaboration with Giovanni Zifarelli and Michael Pusch, and published in The Journal of Physiology

Read it here:

https://physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/JP282737

BUT WAIT--THERE'S MORE...

This article was highlighted in a Perspectives piece

Want to hear ClC-6 sing? Push your amp to eleven by the inimitable William Kobertz. You can read it by clicking the link below:

https://physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/JP283060