Department of Chemistry

Dr. Ryan J. Rafferty
Ryan J. Rafferty

Associate Professor

location CBC 203
email rjraff@ksu.edu
Research Themes
Design and Synthesis of Molecules and Supramolecular Architecturesblank spacerFunctional Materials, Catalysis, and Nanochemistryblank spacerDesign and Synthesis of Molecules and Supramolecular Architectures
email

Biography

2020-Pres.

2024-Pres.

2014-2020

2011-2014

2012-2014

2005-2011

2006-2009

2001-2004

2000-2002
1996-2000

Associate Professor

Assistant to the Director of Johnson Cancer Research Center

Assistant Professor

Postdoctoral Researcher, University of Illinois at Urbana

Visiting Lecturer of Organic Chem., Univ. of Illinois at Urbana

Ph.D., Synthetic Organic Chemistry, Colorado State Univ.

Visiting Lecturer of Organic Chem., Colorado State Univ.

M.S., Biochemistry, University of Northern Colorado

B.S., Biology, University of Northern Colorado
B.A., Chemistry (Biochemistry Emphasis), University of Northern Colorado

Research Overview

Dr. Rafferty's research focuses in synthetic organic chemistry, drug discovery, medicinal chemistry, probing the transport of small molecules across complex cellular barriers, and the development of personalized cancer therapeutics. Students and postdoctoral fellows that join the group will receive training at the interface of chemistry and biology through the acquired skills and combinations of synthetic organic chemistry, medicinal chemistry, and chemical biology.
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Selected publications
  • Rafferty, R.J., Hicklin, R. W., Maloof, K. A., and Hergenrother, P. J. “Synthesis of Complex and Diverse Compounds via Ring Distortion of Abietic Acid.” Angew. Chem. Int. Ed. 2014, 53, 220-224.
  • Rafferty, R. J. and Williams, R. W. “Formal Synthesis of Hapalindole O and Efforts Towards Ambiguine A.” Heterocycles, 2012, 86, 219-231.
  • Rafferty, R. J. and Williams, R. W. “Total Synthesis of Hapalindoles J and U.” J. Org. Chem. 2012, 77, 519-524.
  • Rafferty, R. J. and Williams, R. W. “Synthetic Studies on the Ambiguine Family of Alkaloids: Construction of the ABCD Ring System.” Tet. Lett.2011, 52(17), 2037.
  • Artman, G.; Rafferty, R. J.; Williams, R. M. “(3R,7aS)-3-(Trichloromethyl)tetrahydro-pyrrolo[1,2-c]oxazol-1(3H)-one: An Air and Moisture Stable Reagent for the Synthesis of Optically Active a-Branched Prolines.” Org. Syn. 2009, 86, 262.