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K-State Today

March 4, 2015

Kansas State Veterinary Diagnostic Laboratory partners with Lawrence Livermore National Laboratory to build high throughput diseases diagnostic panel

By Jianfa Bai

Pejman Naraghi-Arani, molecular virologist, assay developer and program manager, and A. Celena Carrillo, lab manager, from Lawrence Livermore National Laboratory, are visiting the Kansas State Veterinary Diagnostic Laboratory through March 5. Their visit is an important next step in transferring a high throughput swine disease diagnostic panel, which was developed at Lawrence Livermore National Laboratory, in close collaboration with K-State's lab.

The Molecular Diagnostic Laboratory at Kansas State Veterinary Diagnostic Laboratory has been developing a variety of diagnostic assays for animal and zoonotic pathogen identification, differentiation and quantification. From this development — through our partnership with Lawrence Livermore National Laboratory — we are moving to the next level of animal diagnostics, called Luminex technology. Luminex technology has many advantages over other diagnostic techniques, which includes the ability to detect several dozen pathogens in a single reaction.

The Luminex swine disease diagnostic panel includes the most common genotypes or serotypes of 10 major pathogens: Porcine Reproductive and Respiratory Syndrome Virus, Swine Influenza virus, Porcine Circovirus, type 2, Pseudorabies Virus, Mycoplasma hyopneumoniae, Actinobacillus pleuropneumoniae, Hemophilus parasuis, Streptococcus suis, African Swine Fever Virus, and Classical Swine Fever Virus.

Kansas State Veterinary Diagnostic Laboratory's continued partnership with entities such as Lawrence Livermore National Laboratory will enable the lab to continually provide cutting-edge, price effective diagnostics, not only for swine diseases, but for multiple species.