Welcome to the Kathrin Schrick Lab in the Division of Biology at Kansas State University in Manhattan, Kansas


Our lab is also affiliated with the Biochemistry and Molecular Biophysics Graduate Group   (BMBGG), Molecular Cellular Developmental Biology Program (MCDB), the Genetics Interdepartmental Graduate Program, the Ecology, Evolution and Genomics Program (EEG), the Kansas Lipidomics Research Center, the Biotechnology Core Facility, and the Johnson Center for Basic Cancer Research.



 

How does an embryo arise from a single cell?  Plant embryos establish an apical-basal axis comprised of organized tissues during early development.  Among the tissues formed are stem cell populations that give rise to the shoot and the root.  Our lab is interested in understanding the molecular mechanisms that underlie pattern formation.


Within the last decade, characterization of a group of sterol biosynthesis mutants of Arabidopsis revealed that sterol composition is crucial for pattern formation. We are investigating the molecular functions of sterols in plants using genetics interfaced with systems biology platforms in genomics, proteomics, and lipidomics as tools.  Our quest to identify new sterol-binding signaling proteins has led to our study of plant-specific homeodomain transcription factors that contain START domains.  A second area of investigation is the role of sterols in cellulose synthesis.  Learn more about our research by navigating this website.
















Our research is funded by the United States Department of Agriculture, the National Science Foundation, and Kansas State University.




 

|   Copyright © Schrick Lab   |    Division of Biology     |    Kansas State University, Manhattan, KS  66506-4901   |   

We do Plant Developmental Biology, Genetics and -Omics

The fackel (fk) seedling pictured here is mutant for the enzyme sterol C-14 reductase.  fk mutants display abnormal embryonic pattern formation, cell division and elongation defects, and are deficient in accumulation of cellulose. This complex phenotype reflects the myriad functions of sterols in plant cells.

last modified  04/11/14