Publications

1) Boyle, D. and L. Takemoto (1994) Characterization of the a-g and a-b complex:Evidence for an in vivo functional role of a-crystallin as a molecular chaperone. Exp. Eye Res. 58:9-16.

2) Takemoto, L. and D. Boyle (1994) Molecular chaperone properties of the high molecular weight aggregate from aged lens. Curr. Eye Res. 13:35-44.

3) Boyle, D. and L. Takemoto (1994) Immunolocalization of the C-terminal and N-terminal region of alpha-A and alpha-B crystallins. Curr. Eye Res. 13:497-504.

4) Takemoto, L. and D. Boyle (1994) Binging of denatured protein decreases the chaperone properties of alpha crystallin. Arch. Biochem. Biophys. 315:133-136.

5) Yan, F.,D.A. Lutz, V.L. Shepherd, D. Boyle, and B.J. McLaughlin (1995) Characterization of rod outer segment plasma membrane proteins which bind to the mannose receptor. Curr. Eye Res. 14:465-471.

6) Boyle, D. and L. Takemoto (1995) EM immunolocalization of a-crystallins: Association with the plasma membrane from normal and cataract human lenses. Curr. Eye Res. 15:577-582.

7) Boyle, D. L., D. S. Blunt and L. J. Takemoto (1997) Confocal microscopy of cataracts from animal model systems : Relevance to human nuclear cataract. Exp. Eye Res. 64;565-572.

8) Boyle, D. L. and L. J. Takemoto (1997) Laser scanning confocal microscopy of human lens membranes in aged normal and nuclear cataracts. Invest. Ophthalmol. Vis. Sci. 38:2826-2832.

9) Takemoto, L. and D. Boyle (1998) The possible role of alpha crystallins in human senile cataractogenesis. Inter. J. Biol. Macromol. 22:331-337.

10) Takemoto, L. and D. Boyle (1998) Determination of the in vivo deamindation of asparagine-101 from alpha-A crystallin using microdissected sections of the aging human lens. Exp. Eye Res. 67:119-120.

11) Takemoto, L. and D. Boyle (1998) Deamidation of specific glutamine residues from alpha-A crystallin during aging of the human lens. Biochem. 37:13681-13685.

12) Boyle, D.L. and L. Takemoto (1998) Finger-like projections of plasma membrane in the most senescent fiber cells of human lenses. Curr. Eye Res. 17:1118-1123.

13) Boyle, D.L. and L. J. Takemoto (1999) Localization of MIP 26 in nuclear fiber cells from aged normal and age-related nuclear cataractous human lenses. Exp. Eye Res. 68:41-49.

14) Takemoto, L. and D. Boyle (1999) Deamidation of alpha-A crystallin from nuclei ofcataractous and normal human lenses. Mol. Vis. 5:2.

15) DL Boyle and L.J. Takemoto (2000) A possible role for a-crystallins in lens epithelial cell differentiation.  Mol. Vis. 6:63-71.

16) Y. Tamada, C.  Fukiage, D.L. Boyle, M. Azuma and T.R. Shearer (2000) Involvement of cysteine proteases in bFGF-induced angiogenesis in guinea pig and rat cornea. J. Ocular Pharmacol. 16:271-283.

17) Wagner LM, Saleh SM, Boyle DL, Takemoto DJ. Effects of protein kinase Cγ on gap junction disassembly in lens epithelial cells and retinal cells in culture. Mol Vis. 2002; 8:59-66. http://www.molvis.org/molvis/v8/a8/

18) Tasheva ES, Koester A , Paulsen AQ, Garrett AS, Boyle DL, Davidson HJ, Song M, Fox N, Conrad GW. Mimecan/osteoglycin-deficient mice have collagen fibril abnormalities. Mol Vis. 2002; 8:407-415.  http://www.molvis.org/molvis/v8/a48/ 

19) Boyle DL, Carman P, Takemoto L. Translocation of macromolecules into whole rat lenses in culture. Mol Vis. 2002; 8:226-234. http://www.molvis.org/molvis/v8/a29/

20) Nguyen TA, Boyle DL, Wagner LM, Shinohara T, Takemoto DJ. LEDGF active of PKCγ and gap junction disassembly in lens epithelial cells. Experimental Eye Res. 2003, 76(5):565-72.

21) Lin D, Boyle DL, Takemoto DJ. IGF-1-induced phosphorylation of connexin 43 by PKC γ: Regulation of gap junctions in rabbit lens epithelial cells. Invest. Ophthalmol Vis. Sci. 2003, 44(3):1160-8.

22) Boyle DL, Takemoto L, Brady JP, Wawrousek EF. Morphological characterization of the alphaA- and alphaB-crystallin double knockout mouse lens. BMC Ophthalmology. 2003, 3:3. [http://www.biomedcentral.com/1471-2415/3/3]

23)  Tasheva ES, Ke An,  Boyle DL,  Conrad G W.. Expression and localization of leucine-rich B7 protein in human ocular tissues. Mol. Vis.  6 July 2005 [Full text]