Subject: This is what will be displayed in the Subject line of the e-note.
From address: This is what will be recipients will see as the From address in the e-note. It does not have to be your e-mail address.
Reply-to address: If recipients reply to your e-note, this is the e-mail address their reply will be sent to. It does not have to be your e-mail address.
Note to be sent: This is the message that will be sent to the audience.