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The Hua Research Laboratory

Hua Research Lab
Kansas State University
Department of Chemistry
301 CBC Building
1212 Mid-Campus Dr North
Manhattan, KS 66506

Phone Numbers
Office: 785-532-6699
Lab: 785-532-6664
Fax: 785-532-6666
Email: duy@ksu.edu

Publications

173. Catalytic Asymmetric Oxidation of Alkenes and Alkanes via Chiral-Substituted Polyvinylpyrrolidinone Stabilized Bimetallic Nanoclusters.  Huafang Fan, Bo Hao, Zongbo Tong, Fei Ma, Kyle Apley, Edruce Edouarzin, Yasaman Etemadi, Zhaoyang Ren, and Duy H. Hua.  J. Org. Chem2019, under revision.  

172. One-Pot Intramolecular Tandem Michael-Aldol Condensation Reaction in the Asymmetric Synthesis of Pentacyclic Terpenes. Jianyu Lu, Serkan Koldas, Huafang Fan, John Desper, and Duy H. Hua.  Synthesis2019, in press.

171. Selective T-type Calcium Channel Inhibitors 1,3,4-Oxadiazoles for Anti-Seizures and Mitigation of Neuropathic Pain.  Man Zhang, Bende Zou, Medha J. Gunaratna, Sahani Weerasekara, Thi D. T. Nguyen, Serkan Koldas, William S. Cao, Christopher Lieu, Conrado Pascual, Xinmin Simon Xie, Duy H. Hua.  Heterocycles2020101, in press.

170. Synthesis of 1,4- and 1,4,4-substituted piperidines for the inhibition of neuronal T-type Ca2+channels and mitigation of neuropathic pain in mice.  Medha J. Gunaratna, Duy H. Hua,Bende Zou, Conrado Pascual,William Cao, Man Zhang,
Sahani Weerasekara,Thi D. T. Nguyen, Kui Xiao, Xinmin Simon Xie. Arkivoc2019, part iii, 22-39.  DOI: https://doi.org/10.24820/ark.5550190.p010.752.

169. Electrochemical Activity Assay for Protease Analysis Using Carbon Nanofiber Nanoelectrode Arrays.  Yang Song, Huafang Fan, Morgan J. Anderson, JestinGage Wright, Duy H. Hua, Jessica Koehne, Meyya Meyyappan, and Jun Li.  Analytical Chemistry201991, 3971-3979.  DOI: 10.1021/acs.analchem.8b05189

168. Synthesis and biological evaluation of steroidal derivatives bearing a small ring as vitamin D receptor agonists.  Norihito Arichi, Shinichi Fujiwara, Michiyasu Ishizawa, Makoto Makishima, Duy H. Hua, Ken-ichi Yamada, Yousuke Yamaoka, and Kiyosei Takasu. Bioorganic & Medicinal Chemistry Letters,2017, 27, 3408-3411. http://dx.doi.org/10.1016/j.bmcl.2017.05.089

167.  The anti-Aband neuroprotective properties of a novel tricyclic pyrone molecule.  Izumi Maezawa, Bende Zou, Jacopo Di Lucente, William S. Cao, Conrado Pascual, Sahani Weerasekara, Man Zhang, Xinmin Simon Xie, Duy H. Hua, and Lee-Way Jin.  Journal Alzheimer’s Disease201758, 559-574.

166. Chiral Substituted Poly-N-vinylpyrrolidinones and Bimetallic Nanoclusters in Catalytic Asymmetric Oxidation Reactions.  Bo Hao, Medha J. Gunaratna, Man Zhang, Sahani Weerasekara, Sarah N. Seiwald, Vu T. Nguyen, Alex Meier, and Duy H. Hua. J. Am. Chem. Soc. 2016, 138, 16839-16848, DOI:10.1021/jacs.6b12113.

165. Study of Class I and Class III Polyhydroxyalkanoate (PHA) Synthases with Substrates Containing a Modified Side Chain.  Kaimin Jia, Ruikai Cao, Duy H. Hua, and Ping Li. Biomacromolecules, 2016, 17(4), 1477-1485. doi: 10.1021/acs.biomac.6b00082.

164. Current Tools for Norovirus Drug Discovery.  Sahani Weerasekara, Allan M. Prior, and Duy H. Hua.  Expert Opinion On Drug Discovery, 2016, 11(6), 529-541. doi: 10.1080/17460441.2016.1178231.

163. Reversal of the progression of fatal coronavirus infection in cats by a broad-spectrum coronavirus protease inhibitor.  Yunjeong Kim, Hongwei Liu, Anushka C. Galasiti Kankanamalage, Sahani Weerasekara, Duy H. Hua, William C. Groutas, Kyeong-Ok Chang, Niels C. Pedersen.  PLOS Pathogens, 2016 (March 30, 2016), 1-18; doi:10.1371/jouran.ppat.1005531.

162. Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels.  Jianyu Lu, Angelo Aguilar, Bende Zou, Weier Bao, Serkan Koldas, Antje Philine Wangemann, Xinmin Simon Xie, and Duy H. Hua.  Bioorganic & Med. Chem. 2015, 23, 5985-5998.  http://dx.doi.org/10.1016/j.bmc.2015.06.055.

161. Quantitative electrochemical detection of cathepsin B activity in breast cancer cell lysates using carbon nanofiber nanoelectrode arrays toward identification of cancer formation. Luxi Z. Swisher, Medha J. G. A. Gamaralalage, Stephanie Shishido, Foram Madiyar, Thu A. Nguyen, Duy H. Hua, and Jun Li.  Nanomedicine: Nanotech., Biol., & Med. 2015, 11, 1695-1704. http://dx.doi.org/10.1016/j.nano.2015.04.014

160. Broad-spectrum protease inhibitors against 3C-like proteases of feline coronaviruses and feline caliciviruses. Yunjeong Kim, Vinay Shivanna, Sanjeev Narayanan, Allan M. Prior, Sahani Weerasekara, Duy H. Hua, Anushka C.  Galasiti Kankanamalage, William C. Groutas, and Kyeong-Ok Chang. J. Virology, 2015, 89(9), 4942-49550. Doi:10.1128/JVI.03688-14.

159.  ­­ Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease. Liang Zhang, Song Zhang, Izumi Maezawa, Sergey Trushin, Paras Minhas, Matthew Pinto, Lee-Way Jin, Keshar Prasain, Thi D. T. Nguyen, Yu Yamazaki, Takahisa Kanekiyo, Guojun Bu, Ben Gateno, Kyeong-Ok Chang, Karl A. Nath, Emirhan Nemutlu, Petras Dzeja, Yuan-PingPang, Duy H. Hua, and Eugenia Trushina.  EBioMedicine 2015, 2, 294-305; doi: 10.1016/j.ebiom.2015.03.009

158. Syntheses, neural protective activities, and inhibition of glycogen synthase kinase-3b of substituted quinolines.  Jianyu Lu, Izumi Maezawa, Sahani Weerasekara, Ramazan Erenler, Tuyen D. T. Nguyen, James Nguyen, Luxi Z. Swisher, Jun Li, Lee-Way Jin, Alok Ranjan, Sanjay K. Srivastava, and Duy H. Hua. Bioorganic and Medicinal Chemistry Letters 2014, 24, 3392-3397. http://dx.doi.org/10.1016/j.bmcl.2014.05.085. Pubmed# 24951331, NIHMSID# 603264, Publ. ID# BMCL21699.

157. Syntheses of 3-[(Alkylamino)methylene]-6-methyl-1H-pyridine-2,4-diones, Fluorescence Probes 3-Substituted 7-Methyl-6H-pyrano[3,2-c]pyridine-2,5-diones, and Tetrahydro-6H-2,10-dioxa-9-azaanthracen-1-ones. Allan M. Prior, Medha J, G, A. Gamaralalage, Daisuke Kikuchi, John Desper, Yunjeong Kim, Kyeong-Ok Chang, Izumi Maezawa, Lee-Way Jin, and Duy H. Hua. Synthesis 2014, 46, 2179-2190. DOI: 10.1055/s-0033-1339027

156. Inhibition of Long Chain Fatty Acyl-CoA Synthetase (ACSL) and Ischemia Reperfusion Injury.  Allan M. Prior, Man Zhang, Nina Blakeman, Palika Datta, Hung Pham, Qian Chen, Lindon H. Young, Margaret T. Weis, Duy H. Hua. Bioorganic and Medicinal Chemistry Letters 2014, 24, 1057-1061. NIHMS557540. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963287

155. Quantitative electrochemical detection of cathepsin B activity in complex tissue lysates using enhanced AC voltammetry at Carbon Nanofiber Nanoelectrode Arrays. Luxi Z. Swisher, Allan M. Prior, Thu A. Nguyen, Duy H. Hua, Jun Li. Biosensors & Bioelectronics. 2014, 56, 129-136. http://dx.doi.org/10.1016/j.bios.2014.01.002

154. Design, Synthesis, and Bioevaluation of Viral 3C and 3C-Like Protease Inhibitors. Allan M. Prior, Yunjeong Kim, Sahani Weerasekara, Meghan Moroze, Kevin R. Alliston, Roxanne Adeline Z. Uy, William C. Groutas, Kyeong-Ok Chang, and Duy H. Hua. Bioorganic and Medicinal Chemistry Letters 2013, 23, 6317-6320. PMCID: PMC 3863581; NIHMSID: NIHMS 529847

153. Macrocyclic Inhibitors of the Picornavirus-like Supercluster 3C and 3CL Proteases.  Sivakoteswara Rao Mandadapu,Pathum M. Weerawarna,Allan M. Prior, Roxanne Adeline Z. Uy, Sridhar Aravapalli, Kevin R. Alliston, Gerald H. Lushington, Yunjeong Kim, Duy H. Hua,Kyeong-Ok Chang, William C. Groutas.  Bioorganic and Medicinal Chemistry Letters, 2013, 23, 3709-3712.

152. Bioavailability and efficacy of a gap junction enhancer (PQ7) in a mouse mammary tumor model.  Stephanie N. Shishido, Keshar Prasain, Amanda Beck, Thi D. T. Nguyen, Duy H. Hua, and Thu Annelise Nguyen.  Plos One 2013, volume 8, issue 6, e67174; doi:10.1371/journal.pone.0067174.

151. Electrochemical Protease Biosensor Based on Enhanced AC Voltammetry Using Carbon Nanofiber Nanoelectrode Arrays.  Luxi Z. Swisher, Lateef U. Syed, Allan M. Prior, Foram Madiyar, Kyle Carlson, Thu Annelise Nguyen, Duy H. Hua, and Jun Li.  J. Phys. Chem. C 2013, 117(8), 4268-4277. dx.doi.org/10.1021/jp312031u.

150. Transport by OATP1B1 and OATP1B3 enhances cytotoxicity of EGCG and certain substituted quercetins.  Yuchen Zhang, Amanda Hays, Alexander Noblett, Mahendra Thapa, Duy H. Hua, and Bruno Hagenbuch.  J. Natural Products, 2013, 76(3), 368-373. dx.doi.org/10.1021/np3007292.

149. Design, Synthesis and Evaluation of Bioactive Small Molecules.  Duy H. Hua, The Chemical Record, 2013, 13(1), 60-69. Published online: December 20, 2012, DOI 10.1002/tcr.201200016. PMID: 23280957.

148. Inhibition of norovirus 3CL protease by bisulfite adducts of transition state inhibitors.  Sivakoteswara Rao Mandadapu, Mallikarjuna Reddy Gunnam, Kok-Chuan Tiew, Roxanne Adeline Z. Uy, Allan M. Prior, Kevin R. Alliston, Duy H. Hua, Yunjeong Kim, Kyeong-Ok Chang, William C. Groutas.  Bioorganic and Medicinal Chemistry Letters, 2013, 23, 62-65. http://dx.doi.org/10.1016/j.bmcl.2012.11.026.

147. Inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT), Overexpression of Cholesterol Transporter Gene, and Protection of Amyloid b (Ab) Oligomers-Induced Neuronal Cell Death by Tricyclic Pyrone Molecules.  Laxman Pokhrel, Izumi Maezawa, Thi D. T. Nguyen, Kyeong-Ok Chang, Lee-Way Jin, and Duy H. Hua.  J. Med. Chem. 2012, 55(20), 8969-8973; http://dx.doi.org/10.1021/jm3012189.

146. Label-free electrochemical impedance detection of kinase and phosphatase activities using carbon nanofiber nanoelectrode arrays.  Yifen Li, Lateef Syed, Jianwei Liu, Duy H. Hua, and Jun Li.  Analytica Chimica Acta, 2012, 744, 45-53. http://dx.doi.org/10.1016/j.aca.2012.07.027

145. The effect of the PQ1 anti-breast cancer agent on normal tissues.   Ying Ding, Keshar Prasain, Thi D. T. Nguyen, Duy H. Hua, and Thu A. Nguyen.  Anti-Cancer Drugs, 2012, 23(9), 897-905. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428498/

144. Synthesis and anti-norovirus activity of pyranobenzopyrone compounds.  Laxman Pokheil, Yunjeong Kim, Thi D. T. Nguyen, Allan M. Prior, Jianyu Lu, Kyeong-Ok Chang, Duy H. Hua.  Bioorganic and Medicinal Chemistry Letters, 2012, 22, 3480-3484. http://dx.doi.org/10.1016/j.bmcl.2012.03.084.

143. Novel triacsin C analogs as potential antivirals against rotavirus infections.  Yunjeong Kim, David George, Allan M. Prior, Keshar Prasain, Shuanghong Hao, Duy D. Le, Duy H. Hua, and Kyeong-Ok Chang.  European J. Med. Chem. 2012, 50, 311-318. PMID: 22365411; PMCID: PMC3312795.

142. Redox Potentials and Laccase and Antilarval Activities of Substituted Phenols.  Keshar Prasain, Thi D. T. Nguyen, Maureen Gorman, Lydia Barrigan, Zeyu Peng, Michael R. Kanost, Lateef U. Syed, Jun Li, Kun Yan Zhu, and Duy H. Hua.  Bioorganic and Medicinal Chemistry, 2012, 20, 1679-1689.

141.  Kinetic properties of alternatively spliced isoforms of laccase-2 from Tribolium castaneum and Anopheles gambiae.  Maureen J. Gorman, Lucinda I. Sullivan, Thi D. T. Nguyen, Huaien Dai, Yasuyuki Arakane, Neal T. Dittmer, Lateef U. Syed, Jun Li, Duy H. Hua, and Michael R. Kanost.  Insect Biochemistry and Molecular Biology, 2012, 42, 193-202.  doi:10.1016/j.ibmb.2011.11.010

140. Synthesis and Antiviral Activity of Substituted Quercetins.  Mahendra Thapa, Yunjeong Kim, John Desper, Kyeong-Ok Chang, and Duy H. Hua.  Bioorganic and Medicinal Chemistry Letters, 2012, 22, 353-356. DOI:10.1016/j.bmcl.2011.10.119. PMID: 22115591; PMCID: PMC3249009. NIHMSID: NIHMS337408

139. Aldose Reductase Inhibitors and Nanodelivery of diabetic therapeutics.  Allan M. Prior, Mahendra Thapa, and Duy H. Hua.  Mini-Reviews in Medicinal Chemistry, 2012, Volume 12,326-336.

138. Design, Synthesis, Property, and Application of Plant Oil Polymers.  Keshar Prasain and Duy H. Hua.  A chapter in “Renewable Polymers: Synthesis, Technology and Processing”.  John Wiley and Scrivener Publishing, USA, 2011, page 23-67.

137. Enhanced Electron Transfer Rates by AC Voltammetry for Ferrocenes Attached to the End of Embedded Carbon Nanofiber Nanoelectrode Arrays.  Lateef U. Syed, Jianwei Liu, Allan M. Prior, Duy H. Hua, and Jun Li.  Electroanalysis, 2011, 23, 1709-1717.  DOI: 10.1002/elan.20110088.

136. Anti-breast Cancer Agents, Quinolines, Targeting Gap Junction. Julie Bernzweig, Brian Heiniger, Keshar Prasain, Jianyu Lu, Duy H. Hua and Thu A. Nguyen.  Medicinal Chemistry, 2011, 7, 448-453.

135. Biodegradable nanogels for oral delivery of interferon for norovirus infection.  Yunjeong Kim, Mahendra Thapa, Duy H. Hua, and Kyeong-Ok Chang.  Antiviral Research, 2011, 87, 165-173.  DOI:10.1016/j.antiviral.2010.11.016. PMC3027895

134. Synthesis of cyclododeciptycene quinones. Kaiyan Lou, Allan M. Prior, Bernard Wiredu, John Desper, and Duy H. Hua.  J. Am. Chem. Soc. 2010, 132, 17635-17641.  Doi: 10.1021/ja1088309.

133. Second generation of substituted quinolines as anti-cancer drugs for breast cancer.  Brian Heiniger, Gunjan Gakhar, Keshar Prasain, Duy H. Hua, and Thu A. Nguyen.  Anticancer Research, 2010, 30, 3927-3932.

132. Bioactivity and molecular targets of novel substituted quinolines in murine and human tumor cell lines in vitro.  Elisabeth M. Perchellet, Kyle R. Crow, Gunjan Gakhar, Thu Annelise Nguyen, Aibin Shi, Duy H. Hua, and Jean-Pierre H. Perchellet.  International J. Oncology, 2010, 36, 673-688.

131. Combinational treatment of gap junctional activator and tamoxifen in breast cancer cells.  Gunjan Gakhar, Duy H. Hua, and Thu Annelise Nguyen.  Anti-Cancer Drugs, 2010, 21(1), 77 – 88; doi: 10.1097/CAD.0b013e328333d557. PMC#4378591.

130. Candidate anti-Ab fluorene compounds selected from analogs of amyloid imaging agents.  Hyun-Seok Hong, Izumi Maezawa, Madhu Budamagunta, Sandeep Rana, Aibin Shi, Robert Vassar, Ruiwu Liu, Kit S. Lam, R. Holland Cheng, Duy H. Hua, John C. Voss, and Lee-Way Jin.  Neurobiology of Aging, 2010, 31, 1690-1699. doi:10.1016/j.neurobiolaging.2008.09.019.

129. Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases.  Yuan-Ping Pang, Fredrick Ekstrom, Gregory A. Polsinelli, Yang Gao, Sandeep Rana, Duy H. Hua, Bjorn Andersson, Per Ola Andersson, Lei Peng, Sanjay K. Singh, Rajesh K. Mishra, Kun Yan Zhu, Ann M. Fallon, David W. Ragsdale, and Stephen Brimijoin.  PLoS One, (Public Library of Science) 2009, 4(8), e6851 (13 pages): http://dx.plos.org/10.1371/journal.pone.0006851. PMC2731169

128. Treatment with tricyclic pyrone compounds reverses cellular phenotype caused by expression of mutant huntingtin protein in striatal neurons.  Eugenia Trushina, Sandeep Rana, Cynthia T. McMurray, and Duy H. Hua.  BMC Neurosci., 2009, 10:73 (Open Access; online publication; 14 pages), doi:10.1186/1471-2202-10-73. PMC2719645

127. Synthesis of Tricyclic Pyrones and Pyridinones and Protection of Ab-Peptide Induced MC65 Neuronal Cell Death.  Sandeep Rana, Hyun-Seok Hong, Lydia Barrigan, Lee-Way Jin, and Duy H. Hua.   Bioorg. & Med. Chem. Lett. 2009, 19, 670-674.  On line: http://dx.doi.org/10.1016/j.bmcl.2008.12.060

126.  Synthesis, molecular targets, and antitumor activities of substituted tetrahydro-1-oxopyrano[4,3-b][1]benzopyrans and nanogels for drug delivery.  Elisabeth M. Perchellet, Jean-Pierre H. Perchellet, Chanran K. Ganta, Deryl L. Troyer, Aibin Shi, and Duy H. Hua.  Anti-Cancer Agents in Medicinal Chemistry, 2009, 9, 864-876.

125. Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule In Vitro and In Vivo.  Hyun-Seok Hong, Sandeep Rana, Lydia Barrigan, Aibin Shi, Yi Zhang, Feimeng Zhou, Lee-Way Jin, and Duy H. Hua.   J. Neurochem. 2009, 108, 1097-1108.

124. Antitumor Effect of Substituted Quinolines in Breast Cancer Cells.  Gunjan Gakhar, Takahiro Ohira, Aibin Shi, Duy H. Hua, and Thu Annelise Nguyen.  Drug Development Research, 2008, 69, 526-534.

123. Protection of Retinal Cells from Ischemia by a Novel Gap Junction Inhibitor.  Satyabrata Das, Dingbo Lin, Snehalata Jena, Aibin Shi, Srinivas Battina, Duy H. Hua, Rachel Allbaugh, and Dolores J. Takemoto.  Biochemical & Biophysical Research Communications, 2008, 373, 504-508. PMCID: PMC2529171

122. Syntheses and Properties of Cross-linked Polymers from Functionalized Triglycerides.  Hui-Ping Zhao, Jian-Feng Zhang, Xiuzhi Susan Sun, and Duy H. Hua.  Journal of Applied Polymer Science,2008, 110, 647-656.

121. Synthesis and Anti-Breast Cancer Activities of Substituted Quinolines.  Aibin Shi, Thu A. Nguyen, Srinivas Battina, Sandeep Rana, Dolores J. Takemoto, Peter K. Chiang, and Duy H. Hua.  Bioorg. & Med. Chem. Lett. 2008, 18, 3364-3368.  http://www.pubmedcentral.gov/articlerender.fcgi?artid=2453686, PMC2453686. PMCID: PMC2453686.

120. Total syntheses of (±)-ovalicin, C4(S*)-isomer, and its C5-analogs and anti-trypanosomal activities.  Duy H. Hua, Huiping Zhao, Srinivas K. Battina, Kaiyan Lou, Ana L. Jimenez, John Desper, Elisabeth M. Perchellet, Jean-Pierre H. Perchellet, and Peter K. Chiang.  Bioorg. & Med. Chem., 2008, 16, 5232-5246. PMC2453514

119. Combination of nanogel polyethylene glycol-polyethlenimine and 6-(hydroxymethyl)-1,4-anthracenedione as an anticancer nanomedicine.  Chanran Ganta, Aibin Shi, Srinivas K. Battina, Marla Pyle, Sandeep Rana, Duy H. Hua, Masaaki Tamura, and Deryl Troyer.  J. Nanoscience and Nanotechnology, 2008, 8(5), 2334-2340.

118. Novel substituted 1,4-anthracenediones with antitumor activity directly induce permeability transition in isolated mitochondria.  Elisabeth M. Perchellet, Yang Wang, Kaiyan Lou, Huiping Zhao, Duy H. Hua, and Jean-Pierre H. Perchellet.  International J. Oncology, 2007, 31, 1231-1241.

117. Antitumor triptycene analogs directly interact with isolated mitochondria to rapidly trigger markers of permeability transition.  Elisabeth M. Perchellet, Yang Wang, Kaiyan Lou, Huiping Zhao, Srinivas K. Battina, Duy H. Hua, and Jean-Pierre H. Perchellet.  Anticancer Research, International Journal of Cancer Research and Treatment, 2007, 27(5), 3259-3272.

116.  The relationship between S-adenosylhomocysteine hydrolase inhibitory activity and hypocholesterolemic activity of D-eritadenine.  Taro Yamada, Junichi Komoto, Kaiyan Lou, Akiharu Ueki, Duy H. Hua, Mikio Sugiyama, and Fusao Takusagawa. Biochem. Pharmacology, 2007, 73, 981-989.

115. Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Ab oligomer-induced cytotoxicity.  Hyun-Seok Hong, Izumi Maezawa, Nianhuan Yao, Ruben Diaz-Avalos, Sandeep Rana, Duy H. Hua, R. Holland Cheng, Kit S. Lam, and Lee-Way Jin.  Brain Research, 2007, 1130, 223-234. PMC1880896

114. Preparation and characterization of nanofibrous perylene-diimide-polyelectrolyte composite thin films.  Thomas A. Everett, Amy A. Twite, Aifang Xie, Srinivas K. Battina, Duy H. Hua, and Daniel A. Higgins.  Chemistry of Materials, 2006, 18(25), 5937-5943.

113.  Syntheses, Molecular Targets and Antitumor Activities of Novel Triptycene Bisquinones and 1,4-Anthracenedione Analogs.  Duy H. Hua, Kaiyan, Lou, Srinivas K. Battina, Huiping Zhao, Elisabeth M. Perchellet, Yang Wang, and Jean-Pierre Perchellet.  Anti-Cancer Agents in Medicinal Chemistry, 2006, 6, 303-318.

112. A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-b oligomeric complexes.  Izumi Maezawa, Hyun-Seok Hong, Hui-Chuan Wu, Srinivas K. Battina, Sandeep Rana, Takeo Iwamoto, Gary A. Radke, Erik Pettersson, George M. Martin, Duy H. Hua, and Lee-Way Jin.  J. Neurochem. 2006, 98, 57-67.

111. Antitumor triptycene analogs induce a rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitrochondria.  Yang Wang, Elisabeth M. Perchellet, Mary M. Ward, Kaiyan Lou, Huiping Zhao, Srinivas K. Battina, Bernard Wiredu, Duy H. Hua, and Jean-Pierre Perchellet.  International Journal of Oncology, 2006, 28(1), 161-172.

110.  Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with antitumor 1,4-anthracenediones.  Yang Wang, Elisabeth M. Perchellet, Mary M. Ward, Kaiyan Lou, Duy H. Hua, Jean-Pierre Perchellet.  Anti-Cancer Drugs, 2005, 16, 953-967.

109. Antitumor triptycene bisquinones induce a caspase-independent release of mitochondrial cytochrome c and a caspase-2-mediated activation of initiator caspase-8 and –9 in HL-60 cells by a mechanism which does not involve Fas signaling.  Elesabeth M. Perchellet, Yang Wang, Rebeka L. Weber, Kaiyan Lou, Duy H. Hua, and Jean-Pierre Perchellet.  Anticancer Drugs, 2004, 15(10), 929-946.

108. Synthesis and Anticancer Actitivity of Substituted Anthracene-1,4-diones.  Duy H. Hua, Kaiyan Lou,Elisabeth M. Perchellet, Yang Wang, Jean-Pierre Perchellet, and Takeo Iwamoto.  Tetrahedron, 2004, 60(45), 10155-10163.

107.Total Syntheses of (+)-Chloropuupehenone and (+)-Chloropuupehenol, and their Analogs, and Evaluation of their Bioactivities.  Duy H. Hua, Xiaodong Huang, Yi Chen, Srinivas K. Battina, Masafumi Tamura, Sang-Kyu No, Sung I Koo, Ichiji Namatame, Hiroshi Tomoda, Elisabeth M. Perchellet, and Jean-Pierre Perchellet.  J. Org. Chem. 2004, 69(18), 6065-6078.

106. Normalization of lens protein kinase Cg in galactosemic dogs by a novel aldose reductase inhibitor.  Dolores J. Takemoto, Richard Harris, Al Brightman, John McGill, Duy H. Hua, Harriet Davidson, Brad Fenwick, and Lynn M. Wagner.  Veterinary Ophthalmology, 2004, 7, 163-167.

105. Antitumor 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3 and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in wild-type and multidrug-resistant HL-60 cells by a mechanism which is partially mediated by caspase-2 activation but is Fas-independent.  Elisabeth M. Perchellet; Yang Wang; Rebeka L. Weber; Bonnie J. Sperfslage; Kaiyan Lou; Justin Crossland; Duy H. Hua; Jean-Pierre Perchellet.  Biochem. Pharmacol, 2004, 67, 523-537.

104. Antitumor triptycene bisquinones: a novel synthetic class of dual inhibitors of DNA topoisomerase I and II activities.  Buna Wang, Elisabeth M. Perchellet, Yang Wang, Masafumi Tamura, Duy H. Hua, and Jean-Pierre Perchellet.  Anti-Cancer Drugs, 2003, 14, 503-514.

103. Antiprotozoal Activities of Symmetrical Bishydroxamic Acids.  Duy H. Hua, Masafumi Tamura, Masahiro Egi, Karl Werbovetz, Dawn Delfin, Manar Salem, and Peter K. Chiang.  Bioorg. & Med. Chem. 2003, 11, 4357-4361.

102. Syntheses and Bioactivities of Tricyclic Pyrones.  Duy H. Hua, Xiaodong Huang, Masafumi Tamura, Yi Chen, Melissa Woltkamp, Lee-Way Jin, Elisabeth M. Perchellet, Jean-Pierre Perchellet, Peter K. Chiang, Ichiji Namatame, and Hiroshi Tomoda.  Tetrahedron, 2003, 59(26), 4795 - 4803.

101. Parallel and perpendicular stacking of ferrocene rings.  Synthesis, x-ray structures, and electrochemistry of 1,8-bis-[1-(1’-phenylthio)ferrocenyl]naphthalene and 8,8’-bis-[1-(1’-phenylthio)ferrocenyl]-1,1’-binaphthyl.  Duy H. Hua, James W. McGill, Kaiyan Lou, Akiharu Ueki, Brian Helfrich, John Desper and Piero Zanello.  Inorganica Chim. Acta. 2003, 350, 259-265.

100.  Unexpected differences in the a-halogenation and related reactivity of sulfones with perhaloalkanes in KOH-t-BuOH, and rotational disorder of the a-haloisopropyl group in its crystalline structures.  Cal Y. Meyers, Roch Chan-Yu-King, Duy H. Hua, Vera M. Kolb, Walter S. Matthews, Thomas E. Parady, Paul B. Sandrock, Yuqing Hou, Songwen Xie, and Paul D. Robinson.  J. Org. Chem.  2003, 68, 500-511.

99. Novel tricyclic pyrone compounds prevent intracellular APP C99-induced cell death. Lee-Way Jin, Duy H. Hua, F. S. Shie, I. Maezawa, B. Sopher, George M. Martin. (2002) In: Drug Discovery and Development for Alzheimer’s Disease. HM Fillit, AW O’Connell, eds. Springer, New York, New York. Page 89-97.

98.  Induction of poly(ADP-ribose) polymerase cleavage by antitumor triptycene bisquinones in wild-type and daunorubicin-resistant HL-60 cell lines.  Yang Wang, Elisabeth M. Perchellet, Masafumi Tamura, Duy H. Hua, and Jean-Pierre Perchellet.  Cancer Letters (Shannon, Ireland), 2002, 188(1-2), 73-83.

97.  Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro.  Elisabeth M. Perchellet, Bonnie J. Sperfslage, Yang Wang, Xiaodong Huang, Masafumi Tamura, Duy H. Hua, and Jean-Pierre Perchellet.  Anti-Cancer Drugs, 2002, 13, 567-581.

96. Syntheses and Bioactivities of Substituted 9,10-Dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones.  Unusual Reactivities With Amines.  Duy H. Hua, Masafumi Tamura, Xiaodong Huang, Heidi A. Stephany, Bonnie J. Sperfslage, Elizabeth M. Perchellet, Jean-Pierre Perchellet, Suping Jiang, Dennis E. Kyle, and Peter K. Chiang.  J. Org. Chem. 2002, 67, 2907-2912.

95. Novel Tricyclic Pyrone Compounds Prevent Intracellular APP C99-induced Cell Death.  Lee-Way Jin, Duy H. Hua, Fang-Shiun Shie, Izumi Maezawa, Bryce Sopher, and George M. Martin.  Journal of Molecular Neuroscience  2002, 19, 57-61.

94.  A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.  Buna Wang, Mingfu Wu, Elisabeth M. Perchellet, Corbin J. McIlvain, Bonnie J. Sperfslage, Xiaodong Huang, Masafumi Tamura, Heidi A. Stephany, Duy H. Hua, and Jean-Pierre Perchellet.  Int. J. Oncol, 2001, 19, 1169-1178.

93.  Synthetic 1,4-Anthracenediones, which block nucleoside transport and induce DNA fragmentation, retain their cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.  Mingfu Wu, Buna Wang, Elisabeth M. Perchellet, Bonnie Sperfslage, Heidi A. Stephany, Duy H. Hua, and Jean-Pierre Perchellet.  Anticancer Drugs, 2001, 12, 807-819.

92. 2-Chloro-2-propyl mesityl sulfone. Cal Y. Meyers, Duy H. Hua, Yuqing Hou, and Paul D. Robinson.  Acta Crystallogr. 2001, Section E, 57, o587-o589.

91.  2,4,6-Tris(1’-phenylthio-1-ferrocenyl)boroxin.  Duy H. Hua, James W. McGill, Paul, D. Robinson, and Cal Y. Meyers. Acta Cryst. 2001, E57, m413-m415.

90.  Short Syntheses of 8’-Substituted 8-[1-(1’-Phenylsulfinyl)ferrocenyl]-1,1’-binaphthyls From the Suzuki Coupling Reactions.  A Strategy For Generating New Chiral Ligands and Charge-Transfer Complexes.  Duy H. Hua, James W. McGill, Masato Ueda, and Heidi A. Stephany.  J. Organomet. Chem. 2001, 637-639, 832-836.

89.  Resolution of 8’-Alkoxy- and Hydroxy-1,1’-binaphthalen-8-ols.  Duy H. Hua, Trieu X. C. Nguyen, James W. McGill, Yi Chen, and Paul D. Robinson.  Tetrahedron:  Asymmetry. 2001, 12(14), 1999-2004.

88. Synthesis and Evaluation of Novel Aldose Reductase Inhibitors: Effects on lens protein kinase Cg.  Sarah Lewis, J. Karrer, S. Saleh, Yi Chen, Zheng Tan, Duy H. Hua, James McGill, Yuan-Ping Pang, Brad Fenwick, Alan Brightman, Dolores J. Takemoto.  Molecular Vision, 2001, 7, 164-171.

87. Cis,cis,cis-Tetramethyl 1,2,4,5-cyclohexanetetracarboxylate.  Paul D. Robinson, Duy H. Hua, Jinmei Fan, Lanzhu Liu, James W. McGill, Mohammed Arshid, and Cal Y. Meyers.  Acta Cryst. 2000, C56, 1471-2.

86. Palladium-Mediated Ring Closure Reactions.  Facile Syntheses of Enantiopure Bicyclic and Tricyclic Alkenones.  Duy H. Hua, Kiyosei Takasu, Xiaodong Huang, Gail S. Millward, Yi Chen, Lan-Zhu Liu, and Jing-Mei Fan.  Tetrahedron 2000, 56, 7389-7398.

85.  1,4-Anthraquinone:  An Anticancer Drug That Blocks Nucleoside Transport, Inhibits Macromolecule Synthesis, Induces DNA Fragmentation and Decreases the Growth and Viability of L1210 Leukemic Cells in the Same Nanomolar Range than Daunorubicin In Vitro.  Elisabeth M. Perchellet, Molly J. Magill, Xiaodong Huang, Dawn M. Dalke, Duy H. Hua, and Jean-Pierre Perchellet.  Anti-Cancer Drugs, 2000, 11, 339-352.

84.  Triptycenes:  a novel synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro.  Elisabeth M. Perchellet, Molly J. Magill, Xiaodong Huang, Cyrille E. Brantis, Duy H. Hua, and Jean-Pierre Perchellet.  Anti-Cancer Drugs, 1999, 10, 749-766.

83.  Tricyclic Pyrone Analogs:  A New Synthetic Class of Bifunctional Anticancer Drugs That Inhibit Nucleoside Transport, Microtubule Assembly, the Viability of Leukemic Cells In Vitro, and the Growth of Solid Tumors In Vivo.  Elisabeth Perchellet, James Ladesich, Molly Magill, Yi Chen, Duy H. Hua, and Jean-Pierre Perchellet.  Anti-Cancer Drugs, 1999, 10, 489-504.

82.  6,7,8,9-Tetrahydro-3-methyl-1H-pyrano[4,3-b]quinolin-1-one.  Duy H. Hua, Yi Chen, Hong-Sig Sin, Paul D. Robinson, Cal Y. Meyers, Elisabeth M. Perchellet, Jean-Pierre Perchellet, Peter K. Chiang, and Jean-Francois Biellmann.  Acta Cryst. 1999, C55, 1698-1701.

81. N-Alkylidenesulfinamides.  Duy H. Hua, Yi Chen, and Gail S. Millward.  Sulfur Reports, 1999, 21 (3), 211-239.

80. Racemic 3-(3,4-dimethoxyphenyl)-1H,7H-5a,6,8,9-tetrahydro-1-oxopyrano[4,3-b][1]benzopyran, an active anticancer agent.  Paul D. Robinson, A. Beatty, Duy H. Hua, Yi Chen, Cal Y. Meyers, Elizabeth M. Perchellet, James B. Ladesich, Jean-Pierre Perchellet.  Acta Cryst. 1999, C55, 1188-1190.

79. Antitumor activity of tricyclic pyrone analogs, a new synthetic class of microtubule-destabilizing agents, in the murine EMT-6 mammary tumor cell line in vitro.  Elisabeth M. Perchellet, James B. Ladesich, Yi Chen, Hong-Sig Sin, Duy H. Hua, Susan L. Kraft and Jean-Pierre Perchellet.  Anti-Cancer Drugs, 1998, 9, 565-576.

78. Chiral Sulfur-Containing 1,2-Disubstituted Ferrocenes.  Nadege M. Lagneau, Yi Chen, Paul M. Robben, Hong-Sig Sin, Kiyosei Takasu, Jin-Shan Chen, Paul D. Robinson, and Duy H. Hua.  Tetrahedron, 1998, 54, 7301-7334.

77.  Tricyclic Pyrone Analogs:  A New Class of Microtubule-Disrupting Anticancer Drugs Effective Against Murine Leukemia Cells In Vitro.  Steven W. Newell, Elisabeth M. Perchellet, James B. Ladesich, Jonathan A. Freeman, Yi Chen, Lan-Zhen Liu, Duy H. Hua, Susan L. Kraft, Randall J. Basaraba, and Jean-Pierre Perchellet.  International Journal of Oncology, 1998, 12, 433-442.

76.  (5aS,7S)-7-Isopropenyl-3-methyl-1H,7H-5a,6,8,9-tetrahydro-1-oxopyrano[4,3-b][1]benzopyran.  Duy H. Hua, Yi Chen, Paul D. Robinson, and Cal Y. Meyers.  Acta Cryst. 1997, C53, 1995-1997.

75.  Cis-3,5a-dimethyl-6-formyloxy-1H,7H-5a,6,8,9-tetrahydro-1-oxopyrano[4,3-b][1]benzopyran.  Paul D. Robinson, Duy H. Hua, Yi Chen, and Cal Y. Meyers.  Acta Cryst. 1997, C53, 1642-1644.

74. Anticancer Activities of 2,5,8,9-Substituted 6-Oxo-1,2,3,4,5,6-hexahydrophenanthridines on Multi-Drug-Resistant Phenotype Cells.  Duy H. Hua, Shankar Saha and Dolores J. Takemoto.  Anticancer Res. 1997, 17, No. 4A, 2435-2441.

73. A One-Pot Condensation of Enals and Pyrones.  Synthesis of Novel 1H,7H-5a,6,8,9-Tetrahydro-1- oxopyrano[4,3-b][1]benzopyrans.  Duy H. Hua, Yi Chen, Hong-Sig Sin, Maria J. Maroto, Paul D. Robinson, Steven W. Newell, Elisabeth M. Perchellet, James B. Ladesich, Jonathan A. Freeman, Jean-Pierre Perchellet, and Peter K. Chiang.  J. Org. Chem. 1997, 62, 6888-6896.

72. Antitumor activity of novel tricyclic pyrone analogs in vitro.  Perchellet, J. P.; Newell, S. W.; Ladesich, J. B.; Perchellet, E. M.; Chen, Y.; Hua, D. H. Proc. Am. Assoc. Cancer Res. 1997, 38, 610-1.

71. Antitumor Activity of Novel Tricyclic Pyrone Analogs in Murine Leukemia Cells in Vitro. J. P. Perchellet; S. W. Newell; J. B. Ladesich; E. M. Perchellet; Y. Chen; D. H. Hua; S. L. Kraft; R. J. Basaraba; H. Omura; and H. Tomoda.  Anticancer Research, 1997, 17, No. 4A, 2427-2434.

70.  (SR,1R,2S)-1-(t-Butylsulfinyl)-2-(hydroxymethyl)ferrocene.  Paul D. Robinson, Duy H. Hua, Nadege Lagneau, Paul M. Robben and Cal Y. Meyers.  Acta Cryst. 1997, C53, 445-447.

69.  (SR*,1S*,2S*)-2-(Hydroxymethyl)-1-(p-toluenesulfinyl)ferrocene.  Paul D. Robinson, Duy H. Hua, Jin-Shan Chen, and Nadege Lagneau.  Acta Cryst. 1996, C52, 2757-2759.

68.  Enantioselective Synthesis of Sulfur-Containing 1,2-Disubstituted Ferrocenes.  Duy H. Hua, Nadege M. Lagneau, Yi Chen, Paul M. Robben, Gary Clapham and Paul D. Robinson.  J. Org. Chem. 1996, 61, 4508-4509.

67.  Characterization of the Antitumor-Promoting Activity of Camptothecin in Sencar Mouse Skin.  Xiao M.Gao; Elisabeth, M. Perchellet; Amy W. Davis; Steven W. Newell; Duy H. Hua; Jean -P. Perchellet.  Carcinogenesis, 1996, 17, 1141-1148.

66. Camptothecin Post-treatments Inhibit the Biochemical Effects Linked to the Tumor-Promoting Component of Carcinogenesis in Mouse Epidermis in Vivo.  Xiao M. Gao, Elisabeth M. Perchellet, Steven W. Newell, Guilan Chen, Duy H. Hua, and Jean-Pierre Perchellet.  Int. J. Cancer 1996, 66, 496-505.

65. Asymmetric Syntheses of Alkaloids and Amino Acids via Chiral Sulfur Containing Compounds.  Hua, D. H.; Chen, J. S. (A review Chapter of a monograph) Advances in Heterocyclic Natural Product Synthesis, W. H. Pearson Ed., JAI Press; Greenwich, Connecticut, vol. 3, 1996, p 151-177.

64.  Gilvocarcins.  Duy H. Hua and Shankar Saha. Recueil des Travaux Chimiques des Pays-Bas 1995, 114, 341-356.

63. (1S,8S,8aS)-(+)-1-(t-Butyldimethylsilyloxy)-8-hydroxy-5-indolizidinone.  Duy H. Hua, Nadege Lagneau, Jewn-Giew Park, Linda A. Good, and Paul D. Robinson.  Acta Cryst. 1995, C51, 2301-2304.

62. Asymmetric Synthesis of a-Amino Acids via Chiral N-Alkylidenesulfinamides.  Duy H. Hua, Nadege Lagneau, Hui Wang, and Jinshan Chen.  Tetrahedron:  Asymmetry, 1995, 6, 349-352.

61. (2S,4R,5R)-(-)-3-Isopropyl-4-methyl-5-phenyl-1,2,3-oxathiazolidine-2-oxide.  Paul D. Robinson, Duy H. Hua, Jinshan Chen, and Nadege Lagneau.  Acta Cryst. 1995, C51, 1372~1374.

60. t-Butyldimethylsilyl trifluoromethanesulfonate.  Hua, D. H.; Chen, J. S. Encyclopedia of Reagents for Organic Synthesis; John Wiley & Son, New York; 1995, Vol. 2, p 876~878.

59. Triisopropylsilyl trifluoromethanesulfonate.  Hua, D. H.; Chen, J. S. Encyclopedia of Reagents for Organic Synthesis; John Wiley & Son, New York; 1995, Vol 7, p 5183~5184.

58. Bromobis(isopropylthio)borane.  Hua, D. H.; Chen, J. S. Encyclopedia of Reagents for Organic Synthesis; John Wiley & Son, New York; 1995, Vol. 1,  p 704~705.

57. Polarization-Selective Photochromic Reaction of Cyclophane in Glassy Poly(methyl methacrylate) Matrix. Kanato, H.; Tran-Cong, Q.; Hua, D. H.  Macromolecules 1994, 27, 7907-7913.

56. Condensation of Lactams with 2-Aminoacetaldehyde Diethyl Acetal.  A One-Pot Synthesis of Bicyclic Imidazoles.  Hua, D. H.; Zhang, F.; Chen, J.; Robinson, P. D. J. Org. Chem., 1994, 59, 5084-5087.

55. Detection of Oxidation Products in Individual Neurons by Fluorescence Microscopy.  Harris, M. E.; Carney, J. M.; Hua, D. H.; Leedle, R. A. Experimental Neurology 1994 129, 95-102.

54. Photoisomerization of tetraethyl 6,8,15,17-tetrahydro-7H,16H,5,18[1'.2']-benzo-9,14-ethenodibenzo[a,h]cyclotetradecene-7,7,16,16-tetracarboxylate.  Structure of Tetraethyl 1H,8H-3a,7b[1',2']-Benzeno-10a,14b-ethenodibenzo[a,e]dicyclopenta[c,g]- cyclooctene-2,2,9,9(3H,10H)-tetracarboxylate as its Methylene Chloride Solvate.  Hua, D. H.; Dantoing, B.; Robinson, P. D.; Tran-Cong, Q.; Meyers, C. Y. Acta Cryst. 1994, C50, 1090-1093.

53. Structure of (4aR,8R,SR)-8-[(4-methylphenyl)sulfinyl]-2,3,4,4a,5,6,7,8-octahydro-4a-quinolinol.  Robinson, P. D.; Hua, D. H.; Wang, H.; Chen, J. S.; Good, L. A. Acta Cryst. 1994, C50, 425-428.

52. Structure of (4S,5S)-4-Methyl-5-phenyl-2-oxazolidinone.  Robinson, P. D.; Hua, D. H.; Good, L. A.; Wang, H.; Meyers, C. Y. Acta Crystallogr. 1993, C49, 1238-1240.

51. Asymmetric Synthesis of b-Amino-g-hydroxysulfoxides.  Khiar, N.; Fernandez, I.; Alcudia, F.; Hua, D. H. Tetrahedron Lett. 1993, 34, 699-702.

50. Conjugate-Addition Reactions of a-Suflinyl Ketimine Anions with a Methyl a-Amidoacrylate.  Concise Asymmetric Total Syntheses of (-)-Slaframine and (-)-6-Epislaframine.  Hua, D. H.; Park, J. -G.; and Katsuhira, T. J. Org. Chem. 1993, 58, 2144-2150.

49. Synthesis of 2,2-Disubstituted 2,5-Dihydro-4-methyloxazoles.  Duy H. Hua, Noureddin Khiar, Fengqi Zhang, Laurent Lambs, Tetrahedron Lett. 1992, 33, 7751-7754.

48. Ethyl (2R,3R,SR)-3-(Ethoxycarbonyloxy)-2-[1-(p-tolylsulfinyl)cyclopropyl]-1-pyrrolidinecarboxylate.  Paul D. Robinson, Duy H. Hua, Xiangyue Wu, Shou Wu Miao, and Muriel Meled, Acta Cryst. 1992, C48, 2088-2090.

47. Retention of Configuration in the Displacement Reactions of 2-Chloro-1,3,2-oxazaphospholidin- 2-one.  Stereoselective 1,4-Addition Reaction of the Anion of Chiral 2-Propenephosphonamide.  Duy H. Hua, Jin Shan Chen, Shankar Saha, Didier Roche, Paul D. Robinson, Roch Chan-Yu-King, Shou Wu Miao, Hui Wang, and Sadahiko Iguchi, Synlett, 1992, 10, 817-820.

46. Structure of Methyl 8,9-Methylenedioxy-1,2,5,6,10b-pentahydro-2-oxobenzo[d]cyclopen[b]azepine- 4-carboxylate.  Duy H. Hua, Yufeng Hong, Shou Wu Miao, and Paul D. Robinson, Acta Cryst. 1992, 1549-1551.

45. Structure of sp-9-Hydroxy-9-Pivaloylfluorene, Product of Base-Catalyzed Autoxidation of ap-9-Pivaloylfluorene.  Cal Y. Meyers, Jennifer L. Tunnell, Paul D. Robinson, Duy H. Hua, and Shankar Saha Acta Cryst. 1992, C48, 1815-1818.

44. Structure of Cis,cis-4,6-diphenyl-2-(2-propenyl)-1,3-dioxa-2-phosphorinane 2-oxide.  Duy H. Hua, Didier Roche, S. Narasimha Bharathi, Xiangyue Wu, and Paul D. Robinson Acta Cryst. 1992, C48, 1866-1868.

43. Structure of (2R,4R,5R)-2-Chloro-3-isopropyl-4-methyl-5-phenyl-1,3,2-oxazaphospholidine 2-Oxide.  Paul D. Robinson, Duy H. Hua, and Didier Roche Acta Cryst. 1992, C48, 923-925.

42. Chiral Sulfinylallyl and a-Sulfinyl Ketimine Anions in Organic Synthesis.  Duy H. Hua.  Advances in Carbanion Chemistry, V. Snieckus Ed., JAI Press; Greenwich, Connecticut, vol. 1, 1992, Vol. 1, p 249-281.

41. An Improved Procedure of the Pechmann Condensation in the Synthesis of 8-Ethyl-trimethoxy- 6H-benzo[d]naphtho[1,2-b]pyran-6-ones.  Structurally related to the Aglycone of Gilvocarcins.  Hua, D. H.; Saha, S.; Roche, D.; Maeng, J. C.; Iguchi, S.; Baldwin, C. J. Org. Chem. 1992, 57, 399-403.

40. Stereoselective Addition Reactions of Chiral N-Benzylidenesulfinamides.  Asymmetric Syntheses ofb- and g-Amino Acids.  Duy H. Hua, Shou-Wu Miao, Jin-Shen Chen, and Sadahiko Iguchi, J. Org. Chem. 1991, 56, 4-6.

39. Asymmetric Total Syntheses of (-)-Lupinine and (+)-Epilupinine viaa-Sulfinyl Ketimine.  Stereo- controlled Reduction ofb-Sulfinyl Enamines.  Duy H. Hua, Shou Wu Miao, Ana A. Bravo, and Dolores J. Takemoto, Synthesis 1991, 11, 970-974.

38. Stereoselective Additions of Chiral a-Sulfinyl Ketimine Anions to Ene Esters.  Asymmetric Syntheses of Indolo[2,3-a]quinolizidine and Yohimbane Alkaloids, Hua, D. H.; Bharathi, S. N.; Panangadan, J.; Tsujimoto, A. J. Org. Chem. 1991, 56, 6998-7007.

37. Structure of Methyl 8,9-methylenedioxy-2-oxo-1,2,3,4,4aa,5,6,10bb-octahydrophenanthridine-5- carboxylate.  Hua, D. H.; Saha, S.; Robinson, P. D. Acta Cryst. 1991, C47, 2737-2739.

36. Structure of 8-Ethyl-4,10,12-trimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one.  Robinson, P. D.; Hua, D. H.; Roche, D.; Saha, S. Acta Cryst. 1991, C47, 2490-2492.

35. Structure of E-(S)-N-a-Methylbenzylidene-p-toluenesulfinamide.  Robinson, P. D.; Hua, D. H.; Chen, J. -S.; Saha, S. Acta Cryst. 1991, C47, 594-596.

34. Structure of (+)-(7S,SS)-1,2,3,5,6,7-Hexahydro-7-methyl-8-(p-toluenesulfinyl)-Indolizinone.  Duy H. Hua, S. Narasimha Bharathi, Atsuko Tsujimo, and Paul D. Robinson.  Acta Cryst. 1990, C46, 1306-1308.

33. The Pechmann Reaction and Regioselective Oxidation with Selenium Dioxide.  Synthesis of the 12-Demethoxydefucogilvocarcin Ring System.  Duy H. Hua, Shankar Saha, Jin Coo Maeng, and Didier Bensoussan.  Synlett 1990, 4, 233-234.

32. Selective Nucleophilic Addition Reactions of Alkyllithium Reagents with N-Trimethylsilyllactams.  Synthesis of Cyclic Ketimines.  Duy H. Hua, Shou-Wu Miao, S. Narasimha Bharathi, Takeshi Katsuhira, and Ana A. Bravo.  J. Org. Chem. 1990, 55, 3682-3684.

31. Asymmetric Total Syntheses of Elaeokanines A and B via a-Sulfinyl Ketimine.  Duy H. Hua, S. Narasimha Bharathi, Paul D. Robinson, and Atsuko Tsujimoto.  J. Org. Chem. 1990, 55, 2128-2132.

30. An Improved Synthesis of (1R,2R)-(-)-a-(1-Isopropylaminoethyl)benzyl Alcohol.  Duy H. Hua, Robert A. Ostrander, Roch Chan-Yu-King and Jeffrey A. McKie, Org. Pre. Pro. Int. 1989, 21, 225-228.

29. Stereoselective Addition Reactions of Chiral a-Sulfinyl Ketimine Anions with Ene Esters.  Facile Asymmetric Syntheses of Indolo[2,3-a]quinolizidine and Yohimbanoid Alkaloids.  Duy H. Hua, S. Narasimha Bharathi, Fusao Takusagawa, Atsuko Tsujimoto, Jagath Panangadan, Mu-Huang Hung, Ana A. Bravo, and Angie M. Erpelding.  J. Org. Chem. 1989, 54, 5659-5662.

28. Regioselective Addition Reactions of Organometallic Reagents with 3-Benzylidene Heterocyclic Imines Leading to the Synthesis of Pyrrolizidines.  Duy H. Hua, Didier Benssousan and Ana A. Bravo.  J. Org. Chem. 1989, 54, 5399-5402.

27. Synthesis and In Vitro Cytotoxic Activity of 1-Phenyl-3-phenylamino-4-(p-toluenesulfinyl)-trans-1,5-hexadiene.  Debra A. Montgomery, Joan E.  Cunnick, M. Jo Coulter, Gurudas Sinai-Zingde, Dolores J. Takemoto, and    Duy H. Hua, Leukemia Research 1988, 12, 591-596.

26. Preparation of (S)-(-)-4-Methyl-2-cyclohexen-1-one, A Useful Chiral Building Block.  Duy H. Hua and S. Venkataraman, J. Org. Chem. 1988, 53, 1095-1097.

25. Asymmetric Synthesis of (+)-Hirsutene.  Duy H. Hua, S. Venkataraman, Robert A. Ostrander, Gurudas -Z. Sinai, Peggy J. McCann, M. Jo Coulter and Min Ren Xu, J. Org. Chem. 1988, 53, 507-515.

24. Enantioselective Total Synthesis of (+)-12,13-Epoxytrichothec-9-ene via Chiral Sulfinylallyl Anions.  Duy H. Hua, S. Venkataraman, Roch Chan-Yu-King and Joseph V. Paukstelis, J. Am. Chem. Soc. 1988, 110, 4741-4748.

23. Remarkable Enantioselective 1,4-Addition Reactions of Chiral Allylphosphonyl Anions (Ambident Nucleophiles) with Cyclic Enones (Ambident Electrophiles).  Duy H. Hua, Roch Chan-Yu-King, Jeffrey A. McKie, and Les Myer, J. Am. Chem. Soc. 1987, 109, 5026-5029.

22. Stereospecific 1,4-Addition Reaction of Sulfinylallyl Anion:  Synthesis of (+)-Pentalenolactone E Methyl Ester.  Duy H. Hua, M. Jo Coulter, and Ibraheem Badejo, Tetrahedron Lett. 1987, 28, 5465-5468.

21. Stereospecific Skeletal Rearrangement Reactions in Bridgehead-Substituted Bicyclo[2.2.2] System Under Netural Conditions.  Duy H. Hua, Wei-Yi Gung,  Robert A. Ostrander, and Fusa Takusagawa, J. Org. Chem. 1987, 52, 2509-2517.

20. Structure of 1(S*),5(S*),S(R*)-1-(3'-p-Toluenesulfinyl-2'-propenyl)-2-methylene-7,7-dimethylbicyclo[3.3.0]octan-3-one.  Duy H. Hua, Ibraheem Badejo, Peggy J. McCann and Fusao Takusagawa, Acta Crystallogr. Sect. C.   1987, C43, 1114-1116.

19. Stereochemistry of Long-Lasting Opiates.  2.  d-Selective Opiate Antagonists and Their Agonist Analoques.  Vera M. Kolb, Duy H. Hua, and William L. Duax, J. Org. Chem. 1987, 52, 3003-3010.

18. Asymmetric Induction in the Addition Reaction of Chiral Sulfinylallyl Anions (Ambident Nucleoph- iles) with Enones (Ambident Electrophiles).  Ring Closure of Enol Thioether Ketones.  Duy H. Hua, S. Venkataraman, M. Jo Coulter and Gurudas Sinai-Zingde, J. Org. Chem. 1987, 52, 719-728.

17. 1-(1'-0xido-4'-pyridyl)-2-piperidinoethyl-4-nitrobenzoate:  A Reagent to Selectively Remove Oxidizing Dianions.  W. L. Tzeng, C. E. Melaon and D. Hua, Analytical Letters, 1986, 19, 553-564.

16. Asymmetric Total Synthesis of (+)-Pentalenene via Chiral Sulfinylallyl Anions.  Hydrolytic Ring Closure of Enol Thioether Ketones.  Duy H. Hua, J. Am. Chem. Soc. 1986, 108, 3835-3837.

15. Stereochemistry of Novel Delta-Selective Opiate Antagonsits.  Vera M. Kolb, Duy H. Hua and William L. Duax, National Institute on Drug Abuse Research Monograph, 1986, 75, 45-48.

14. Synthesis of 4-Substituted 2-Azetidinones.  Duy H. Hua and Akhilkumar Verma, Tetrahedron Lett. 1985, 26, 547-550.

13. Studies on the Asymmetric Total Synthesis of Trichothecenes.  Stereo-selective Construction of the C-Ring Fragment.  Duy. H. Hua and S.  Venkataraman, Tetrahedron Lett. 1985, 26, 3765-3768.

12. Asymmetric Synthesis via Chiral Sulfinylallyl Anions.  Total Synthesis of (+)-Hirsutene:  Facile Ring Closure Involving Enol Thioether and Enol Acetate Moieties.  Duy H. Hua, Gurudas Sinai- Zingde and S. Venkataraman, J. Am. Chem. Soc., 1985, 107, 4088-4090.

11. Methods for the Interconversion of Protective Groups.  Transformation of MEM Ethers into Isopropylthiomethyl Ethers or Cyanomethyl Ethers.  E. J. Corey, Duy H. Hua and Steven P. Seitz, Tetrahedron Lett., 1984, 25, 3-6.

10. Syn-Anti Isomerism in the Opiate Hydrazones and Azines Derived from Naloxone, Naltrexone, and Oxymorphone.  Vera M. Kolb and Duy H. Hua, J. Org. Chem., 1984, 49, 3824-3828.

 9. Total Synthesis of Aplasmomycin.  E. J. Corey, Duy H. Hua, Bai-Chuan Pan and Steven P. Seitz, J. Am. Chem. Soc., 1982, 104, 6818-6820.

 8. Total Synthesis of Aplasmomycin.  Stereocontrolled Construction of the C(3)-C(17) Fragment.  E. J. Corey, Bai-Chuan Pan, Duy H. Hua and Donald R. Deardorff, J. Am. Chem. Soc. 1982, 104, 6816-8.

 7. Studies with Trialkylsilyltriflates:  New Syntheses and Applications.  E. J. Corey, Hidetsura Cho, Christoph Rucker and Duy H. Hua, Tetrahedron Lett., 1981, 22, 3455-3458.

 6. Synthesis of a Sulfone a-Tosylate, Benzyl (Tosyloxy)methyl Sulfone.  Duy H. Hua, Nancy J. Peacock and Cal Y. Meyers, J. Org. Chem. 1980. 45, 1717-1719.

 5. Unexpected Behavior of an a-tosyloxy Sulfone Compared with an a-Chloro Sulfone in Based- Induced Reactions.  Cal Y. Meyers, Duy H. Hua and Nancy J. Peacock, J. Org. Chem. 1980, 45, 1719-1720.

 4. Total Synthesis of Maytansine.  E. J. Corey, Leland O. Weigel, A. Richard Chamberlin, Hidetsura Cho and Duy H. Hua, J. Am. Chem. Soc. 1980, 102, 6613-6615.

 3. 1,7-Ramberg-Backlund Reaction and Other Anomalous Reactions of p-Hydroxyphenyl a-Halo Sulfones.  Cal Y. Meyers and Duy H. Hua,  Phosphorous and Sulfur, 1979, 6, 197.

 2. Dehydrochlorination of a-Chloro Sulfones with KOH-t-BuOH:  Kinetic vs Equilibrium Control.  Vera M. Kolb, Duy H. Hua and Cal Y. Meyers,  Phosphorous and Sulfur, 1979, 6, 165.

1. Substituent Effects on the Disposition of Thiirane 1,1-Dioxides and Thiirene 1,1-Dioxides in the KOH-t-BuOH.  Cal Y. Meyers, W. S. Matthews, G. J. McCollum, L. L. Ho and Duy H. Hua, Heterocycles, 1978, 9, 1476.