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Media Relations and Marketing
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Manhattan, KS 66506-0117
Phone: 785-532-6415
Fax: 785-532-6418

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Please note: Media Relations is unable to answer questions about pet health problems. Contact your veterinarian.  

Source: Kenneth Harkin, 785-532-4251, harkin@vet.k-state.edu
http://www.vet.ksu.edu/depts/ClinicalSciences/faculty/harkin.htm
News release prepared by: Amber Haag, 785-532-6415

Thursday, February 24, 2005

CATS SHOULD BE TESTED EARLY FOR FELINE LEUKEMIA

MANHATTAN -- As HIV does in people, the feline leukemia virus inserts a copy of its DNA into a cat's cells. These cells may later be transformed into cancer cells or cells that no longer function normally.

Dr. Kenneth Harkin, associate professor of clinical sciences at Kansas State University's College of Veterinary Medicine, said any cat can be affected, but chances decrease as the cat grows older.

"If they are less than 8 weeks old and get exposed to the virus, the chances of contracting it are close to 100 percent," Harkin said. "Under 1 year in age, cats have a 70 percent chance of contracting the virus if exposed. In adult cats, the risk drops to less than 20 percent if exposed. Generally, cats have become better at developing an immune response at this age."

Harkin said some symptoms of the feline leukemia virus, or FeLV, can include weakness and/or difficulty eating or breathing. He also said the infection may be characterized by large lymph nodes and a "scraggly" coat.

Harkin said three major disease categories associated with FeLV are lymphosarcoma, the leukemias and a variety of non-cancerous diseases.

Lymphosarcoma is the most common. Cats with the feline leukemia virus have approximately a 60-fold higher risk of developing this cancer compared to uninfected cats, Harkin said.

Lymphosarcoma is a cancer that begins in lymphoid tissue, such as a lymph node. Almost any tissue can be affected by the cancer. Organs commonly affected include lymph nodes, intestinal tract, kidneys, liver, spinal cord, brain, bone marrow and blood.

The leukemias are cancers of the white blood cells. Leukemia was the first cancer linked with FeLV.

Other non-cancerous diseases vary. Anemia and immune suppression are examples, Harkin said. When the immune system is suppressed, mild diseases can become potentially fatal.

Harkin said a cat can be exposed to feline leukemia in one of two ways: from mother cat to kitten, or from cat to cat.

If a mother cat is infected, her kittens can be infected while in the womb or through milk after birth. Harkin said the odds are that most kittens will be infected if the mother cat is infected.

Harkin said it is more difficult for cats to contract the virus from cat to cat. He said the most common way the virus passes from cat to cat is through saliva in feeding dishes.

Harkin said the most important step an owner can take to prevent a cat being infected with the feline leukemia virus is to test the cat before bringing it into his or her household.

"There is no reason to vaccinate a cat that lives indoors by itself or with other FeLV-negative cats. You need to know the FeLV status of a new cat before you introduce it to your other cats," Harkin said. "The key is to have your cat in a closed-colony environment where it could not possibly come into contact with infected cats. This leaves no chance for infection with the virus."

If the cat tests negative but will be moving into an open-colony household -- a household where cats go inside and outside -- Harkin said the cat should be vaccinated. However, he said this option is not as ideal as keeping the cat in a closed-colony environment and not vaccinating.

"Vaccination is not 100 percent effective and can result in vaccine-induced sarcoma, or a type of cancer," Harkin said. "Although the chance is relatively low, it would be better to keep your cat in a closed colony and not take any chances."

Treatments for the feline leukemia virus vary depending on the disease. However, even with treatment, Harkin said the survival times for cats infected with FeLV are short.

If your cat is infected with FeLV, Harkin said to be sure it doesn't come into contact with other cats.

"The best thing is to keep it exclusively indoors and isolate it from other cats in your household. Letting an infected cat go outdoors increases the risk of it contracting other infectious diseases that may be fatal," Harkin said. "The infected cat has the best chance of long-term survival indoors. We also want to minimize the potential spread of FeLV to other cats."

 

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