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Research Foundation

Compositions and Methods for Controlling Plant Parasitic Nematodes

Reference Number: 00-29

Inventors: Harold Trick, Judith Roe, Timothy Todd, and Michael Herman


The current methods for controlling parasitic nematodes are the use of nonhost crops and resistant variety crops. When resistance is available, the decline in populations is usually slow and elimination is unlikely. Adaptation to resistant varieties poses a significant threat to the long-term management of this pest. Research at Kansas State University has developed novel compositions and methods for controlling nematode infestation of plants or animals. The present invention provides vectors comprising of sequences designed to control nematodes by RNA interference (RNAi) and transgenic plants transformed with such vectors.


  • Provides methods of creating transgenic plants by transfecting a plant or plant tissue with an inhibiting nematode RNA sequence
  • This will inhibit proliferation of nematode generations, greatly reducing infestation compared to the current methods
  • Allows ability to plant desired crops
  • Resistant crops are not needed under present invention, eliminating risk of adaptation of nematodes


  • Agriculture
  • Lawn care
  • Animal care

Patent Status

  • U.S. patent #7,803,984 issued on September 28, 2010.

Kansas State University Research Foundation seeks to have discussions with companies that are interested in licensing and/or research collaborations.

Interested parties should contact:

Kansas State University Institute for Commercialization (KSU-IC)
2005 Research Park Circle Manhattan, KS 66502
Tel: 785-532-3900 Fax: 785-532-3909
E-Mail: ic@k-state.edu