Plant Susceptibility Gene Strategy Leads to Durable Resistance against Hessian Fly, Powdery Mildew, and Potentially Other Pests
Reference Number: K 09-21
Inventors: Trick, Harold; Liu, Xuming; Chen, Ming-Shun
Owner: Kansas State University Research Foundation
USPTO Link:
Invention Summary
Hessian fly and other parasites of plants have long been a devastating problem for
agriculture resulting in substantial industry losses. Current control, by way of
resistance genes, are short lived and only provide resistance to certain biotype(s)
(races) thus limiting the wide adaptation of cultivars with resistance to multiple
pests. Recent research suggests approximately 70% of these genes are no longer effective
in warding off Hessian fly, reinforcing the need for new strategies to minimize losses.
Researchers at Kansas State University have discovered a plant gene, Mds-1, as a
target for manipulation by Hessian fly larvae and the powdery mildew fungus. Our
unique approach obstructs the parasite’s manipulation of host plants by preventing
the expression of a plant susceptibility gene at the attacking site. More specifically,
transgenic plants with a construct produce double stranded RNA which then prevents
the induction of this gene by the Hessian fly attack and in turn prevents the larvae’s
survival. Our research shows this transgene has no apparent negative effects on other
traits of transgenic plants and we expect further research to conclude broad, effective
resistance against other pests.
Advantages
- Durable due to it being biotype independent
- Single gene manipulation leads to resistance against multiple pests
- Potentially allows reinforcement of fly free date and earlier planting
Applications
Control of Hessian fly and other destructive pests such as insect herbivores including: rice midge, orange blossom midge, aphids and others.