Gary W. Conrad, Ph.D.,
John M. Tomich, Ph.D., and Ruth Welti, Ph.D., Co-Directors
Post-translational/post-synthetic modifications of proteins,
lipids, polysaccharides, and other classes of molecules
often determine the biological activities of the entire
macromolecule. Such modifications very often consist of O-,
and/or N-linked glycosylations, some of which can be very
large. Some glycosylation reactions occur very rapidly,
alternating with phosphorylation events at those same sites.
The Glycomics Center therefore has chosen to study
glycosylation of molecules in particular, but also other
structural modifications that often are or may be related to
glycosylation biosynthetically (e.g., O-GlcNAc alternating
with phosphorylation) or structurally (e.g., receptor
molecules that react with specific glycosylated groups).
Currently, the Glycomics Center consists of a group of
investigators in several departments at Kansas State
University interested in sharing their expertise with one
another in studies of post-translational/post-synthetic
modifications, especially (but not exclusively)
glycosylation and glycosylation-related cross-linking.
programs in the Glycomics Center are underway:
The Glycomics Center is submitting grant applications
seeking funds for purchase of high-end instrumentation which
will be housed in a central facility in Ackert Hall on the
campus of Kansas State University. Such instruments will
include mass spectrometers and laser capture microdissection
devices, for example. Those faculty who participate in
writing these applications by submitting text information
required by granting agencies will receive priority for
analysis time on the instruments that are purchased if these
applications are successful. More participating faculty are
welcome to join us. Contact us below.
The Glycomics Center has initiated a discussion group (“Glycomics
Focus Group”) that will meet
for 1 hour each month to discuss research topics. An initial
meeting to allow interested faculty to introduce themselves
to one another and take 5 min maximum to describe their
research interests that may be relevant to the Glycomics
Center will occur on
Tuesday, Jan. 9, 2007, at NOON in AK 107.
Subsequent Tuesday meetings of the Glycomics Focus Group are
13, Mar. 6, Apr. 3, and May 1.
Glycomics Center will add other features to its homepage as
funding allows. If you are interested in participating in
writing grant applications and/or in the Glycomics Focus
Group, feel free to join us at the days and times above.
contact Yuntao Zhang, Ph.D., operational manager of
instrumentation in the Glycomics Center: