Ecological, physiological and genetic consequences of environmental toxins
Brown and Wisely
100 years of lead and zinc mining have introduced high levels of these
metals into the soil and groundwater in the tri-state area of Kansas,
Missouri and Oklahoma. With more than 75,000 people living near the
2,500 mi2 Tri-State Mining District site, it is essential to
understand how these contaminants have influenced the biological landscape
of this region. We will study the effects of contamination on
physiology, genome function, gene expression and population ecology of the
white-footed mouse (Peromyscus leucopus) by comparing individuals and
populations from contaminated and non-contaminated (control) sites.
Yi, L., S. Lu, F. Fotouhi, Y. Deng, and S. Brown (2004). Incremental Genetic K-means Algorithm and its Application in Gene Expression Data Analysis, Bioinformatics. In press.