Examples of Options for Management Plans
- Public disclosure of the financial interests of Investigators in a research sponsor on all publications and in oral presentations.
- Annual or more frequent report to the COI Committee of status and changes in the relationship and the research.
- Reformulation/modification of the protocol.
- Monitoring of research by an independent reviewer(s).
- Double blind data analysis.
- Disclosure in informed consent forms and to human subjects who are participating in clinical trials.
- Informed consent from human subjects obtained by person(s) other than investigator and supervisees.
- Data analysis and interpretation by independent reviewers or review of raw data and manuscript by an external independent reviewer.
- Close monitoring of the conduct of the research by an oversight body.
- Divestiture of relevant personal interests in the research sponsor.
- Disqualification of the investigator's involvement in all or part of the project.
- Protection of the academic rights and interests of students/fellows, if any are involved in the project.
- Severance of the external relationship.
Distinction between the management plans for basic bench research and clinical research involving human subjects should be made.