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Kansas State University

PROGRAM OVERVIEW



A Center of Biomedical Research Excellence (COBRE) award to the College of Veterinary Medicine (CVM) at Kansas State University (KSU) provides the resources needed to elevate the research projects of basic researchers and clinician-scientists at Kansas institutions so they successfully compete for independent NIH funding. The center and its projects also provide a strong foundation for translational research at KSU.

The theme of the COBRE is epithelial function in health and disease, and its projects focus on epithelial cell physiology or pathophysiology. Epithelia are cell layers that line the body’s vital organs and glands and that actively secrete and absorb substances, prevent microbial and viral invasions, and support sensory functions. A clearer understanding of the molecular basis of epithelial function will enable us to better identify disease states and devise therapies for them.

The COBRE supports three core facilities and seven faculty member/mentor teams. COBRE facilities include a state-of-the-art confocal microfluorometry and microscopy facility; a molecular biology and biochemistry support facility; and an epithelial electrophysiology facility. Team members and mentors are faculty of the KSU CVM and collaborating departments at KSU, the University of Kansas, the University of Kansas Medical Center, and Wichita State University.

The COBRE benefits greatly from KSU CVM’s strong support of its basic science and clinical faculty. That support, combined with the additional monetary and programmatic support provided by the COBRE, will ensure the success of COBRE projects and full realization of the potential of our talented faculty.