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Department of Chemistry

Dr. Ryan J. Rafferty

raffertyAssistant Professor

B.A., Chemistry, University of Northern Colorado (2000)
B.S., Biology, University of Northern Colorado (2003)
M. Sc., Biochemistry, University of Northern Colorado (2003)
Ph.D., Synthetic Organic Chemistry (Total Synthesis), Colorado State University (2010)
Postdoctoral Research Fellow, University of Illinois at Urbana-Champaign (2013)
Visiting Lecturer of Organic Chemistry, University of Illinois at Urbana-Champaign (2013)

Email: rjraff@ksu.edu
Office: CB 203
Office Phone: 785-532-6624
Lab Phone: 785-532-6257
Fax: 785-532-6668

Website: Rafferty Research Laboratory 

Research Overview

Dr. Rafferty's research focuses in synthetic organic chemistry, drug discovery, medicinal chemistry, probing the transport of small molecules across complex cellular barriers, and the development of personalized cancer therapeutics. Students and postdoctoral fellows that join the group will receive training at the interface of chemistry and biology through the acquired skills and combinations of synthetic organic chemistry, medicinal chemistry, and chemical biology.

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Five-Selected Publications
  • Rafferty, R.J., Hicklin, R. W., Maloof, K. A., and Hergenrother, P. J. “Synthesis of Complex and Diverse Compounds via Ring Distortion of Abietic Acid.” Angew. Chem. Int. Ed. 2014, 53, 220-224.
  • Rafferty, R. J. and Williams, R. W. “Formal Synthesis of Hapalindole O and Efforts Towards Ambiguine A.”Heterocycles, 2012, 86, 219-231.
  • Rafferty, R. J. and Williams, R. W. “Total Synthesis of Hapalindoles J and U.J. Org. Chem. 2012, 77, 519-524.
  • Rafferty, R. J. and Williams, R. W. “Synthetic Studies on the Ambiguine Family of Alkaloids: Construction of the ABCD Ring System.”Tet. Lett.2011, 52(17), 2037.
  • Artman, G.; Rafferty, R. J.; Williams, R. M. “(3R,7aS)-3-(Trichloromethyl)tetrahydro-pyrrolo[1,2-c]oxazol-1(3H)-one: An Air and Moisture Stable Reagent for the Synthesis of Optically Active a-Branched Prolines.”Org. Syn. 2009, 86, 262.