Dr. Christopher T. Culbertson
B.S., Biology, Harvard College (1988)
B.S., Chemistry, University of West Florida (1991)
Ph.D., University of North Carolina at Chapel Hill (1996)
Postdoctoral Associate, Oak Ridge National Laboratory (1996-8)
Research Scientist, Oak Ridge National Laboratory (1998-2002)
Office Phone: 785-532-6685
Lab Phone: 785-532-7285
Website: Culbertson Group
The research interests of our group are focused on developing novel separation and sample handling components for microfluidic (Lab-on-a-Chip; μTAS) devices and then using these devices to solve interesting bioanalytical problems with special emphasis in the areas of protein separations (proteomics) and single cell analysis. This research is multidisciplinary in nature drawing upon knowledge in the fields of chemistry, physics, engineering, cell biology, and biochemistry.
Sadeghi, J.; Patabadige, D.E.W.; Culbertson, A.H.; Latifi, H. and Culbertson, C.T. Out-of-plane integration of a multimode optical fiber for single particle/cell detection at multiple points on a microfluidic device with applications to particle/cell counting, velocimetry, size discrimination and the analysis of single cell lysate injections. 2016 Lab Chip. Just Accepted DOI: 10.1039/c6lc01161f
Patabadige, D.E.W.; Sadeghi, J.; Latifi, H.; Culbertson, A.; and Culbertson, C.T. Integration of Optical Fibers with Multilayer Microfluidic Devices for Single Cell Analysis, 2016, Analytical Chemistry, ASAP article. DOI: 10.1021/acs.analchem.6b03133.
Patabadige, D.E.W.; Mickleburgh, T.; Ferris, L.; Brummer, G.; Culbertson, A. and Culbertson, C.T. High Throughput Microfluidic Device for Single Cell Analysis using Multiple Integrated Soft Lithographic Pumps, 2016, Electrophoresis, 37(10) pp. 1337-1344 DOI: 10.1002/elps.201500557
Patabadige, D.E.W.; Jia, S.; Sibbitts, J.; Sadeghi, J.; Sellens, K.; and Culbertson, C.T. Micrototal Analysis Systems: Fundamental Advances and applications. 2016, Analytical Chemistry 88(1), pp. 320-338. DOI: 10.1021/acs.analchem.5b04310
Madiyar, FR; Saheel, B; Swisher, LZ; Culbertson, CT; Huang, X; Li, J. Integration of a nanostructured dielectrophoretic device and a surface-enhanced Raman probe for highly sensitive rapid bacteria detection. 2015. Nanoscale. 7(8), pp. 3726-3736.
Culbertson, CT; Mickleburgh, TG; Stewart-James, SA; Sellens, KA; Pressnall, M. Micro Total Analysis Systems: Fundamental Advances and Biological Applications. Analytical Chemistry, 2014, 86(1), pp 95–118.
Metto, EC; Evans, K; Barney, P; Culbertson, AH; Gunasekara, DB; Caruso, G; Hulvey, MK; Fracassi da Silva, JA; Lunte, SM; Culbertson, CT. An Integrated Microfluidic Device for Monitoring Changes in Nitric Oxide Production in Single T-Lymphocyte (Jurkat) Cells, Analytical Chemistry, 2013, 85(21), 10188-10195.