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Department of Biochemistry and Molecular Biophysics

Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
1711 Claflin Rd.
Manhattan, KS 66506
785-532-6121
785-532-7278 fax
biochem@k-state.edu

Biotechnology Core Facility
206 Burt Hall
785-532-5956
785-532-6297 fax

Biomolecular NMR Facility
37 Chalmers Hall
785-532-2345

Recent Department Achievements

"First Graduating Class of BMB Medical Biochemistry Majors Achieve 100% Acceptance to the University of Kansas School of Medicine"

Image of six students accepted to KU from left to right: Natalie Ost, Matthew Brettmann, Samuel Broll, Tate Gilchrist, Mackenzie Wahl, and Garrison Olds.

Photo by Maxwell Braasch

The Department of Biochemistry and Molecular Biophysics is pleased to report that all of its undergraduate majors who applied to the 2021 Class of the University of Kansas School of Medicine were accepted. The students are in order left to right: Natalie Ost, Matthew Brettmann, Samuel Broll, Tate Gilchrist, Mackenzie Wahl and Garrison Olds. All six of these seniors participated in the recently developed Medical Biochemistry track, which BMB created in 2013 for its undergraduate students. This curriculum allows biochemistry students who desire a career in medicine or other health-related fields to both prepare for entrance exams and focus their classroom study on subject matter that will comprise their first year of medical, veterinary or nursing school. In 2016, the overall acceptance rate for US applicants to in-state medical schools was 60.6%, so K-State BMB's 2017 acceptance rate of 100% was well above the norm. (Read full pdf article.)

Alumni Note

  • D. Fernando Estrada (B.S. 1999) was featured in ASBMB Today, a publication of the American Society of Biochemistry and Molecular Biology, as the Research Spotlight on May 1.

Faculty Achievements

  • John Tomich is featured in K-State news as Phoreus Biotechnology licenses his team's bio-delivery technology known as BAPCs. K-State Today.
  • John Tomich and Gerald Reeck recognized for their work in developing "nanomaterial that delivers targeted, lethal rations to insect pests." K-State Today.
  • Gregory Finnigan received an NIH Kansas-INBRE grant for "Molecular analysis of septin function during MAPK-mediated cellular transitions", May 1, 2018 - April 30, 2020. ($218,042)

Student Awards and Scholarships

  • Miao Li was awarded the Biochemistry and Molecular Biophysics Charlie Hedgcoth, Jr. and Phillip Nordin Graduate Memorial Award for Excellence in Graduate Research.
  • Miao Li, Pavithra Natarajan, and Indhujah Thevarajan were awarded the Biochemistry and Molecular Biophysics Charlie Hedgcoth, Jr. and Phillip Nordin Graduate Memorial Award for Excellence in Graduate Teaching for 2017-2018.
  • Isabel Lewis (undergrad, Finnigan) has received an Arts and Sciences Research Award for Summer 2018.
  • Simranjot Bawa (grad, E. Geisbrecht) received a Graduate Student Council Travel Award ($450) to attend the Society for Developmental Biology 77th Annual Meeting in Portland, OR, July 20-24.
  • Yanan Xhou (BMB grad, Yang - Biology) received a Graduate Student Council Travel Award ($400) to attend ASV 2018, the American Society for Virology 37th Annual Meeting, at the University of Maryland in College Park, July 14-18.
  • Erianna Basgall (undergrad, Finnigan) was awarded the American Society for Microbiology Undergraduate Research Fellowship ($6000) for summer 2018.
  • Wolf Blaser, Samantha Goetting, Ethan Kallenberger, Haley Lindell, Mackenzie Penny, and Marta Stetsiv (BMB Undergrads) received Junior Merit Awards from Gamma Sigma Delta the Honor Society of Agriculture.
  • Micah Meyer (BMB undergrad) was selected as a member of the Chimes Junior Honorary for 2018-2019 school year. announcement
  • James Houghton (BMB undergrad) received the $1000 Michael E. Brown Alpha Tau Omega Mortar Board Leadership Scholarship. announcement
  • Michelle Coca Mora (undergrad, Gorman) received the James R. Coffman Award of Excellence in Research Honorable Mention for first year students in the Developing Scholars Program.
  • Carolina Fonte, Reina Garcia, Sarah Gillaspie, and Madeline Woodard (BMB undergrads) have been elected to the Kansas State University Chapter of Phi Beta Kappa academic honor society. Spring 2018
  • Bailey Porter (BMB undergrad) selected for the Staley School of Leadership Studies 2018-2019 class of Snyder Leadership Legacy Fellows. announcement
  • Vaithish Velazhahan, (BMB undergrad, Schrick - Biology) was the first K-State student and one of 35 US students to receive the Gates-Cambridge Scholarship in 2018. This scholarship covers the full cost of studying at Cambridge while pursuing a full-time postgraduate degree. announcement
Fall 2018 K-State Johnson Cancer Center Undergraduate Cancer Research Awards

Announcement. BMB undergraduate and mentor unless otherwise noted.

  • Baltazar Claro Martinez – Mentor: John Tomich - "Development of Timed-Release Peptide Nano-Capsules"
  • Michelle Coca - Mentor: Maureen Gorman - "Mechanisms of regulated iron uptake by cells"
  • Hawa Dembele – Mentor: Om Prakash - "NMR Studies of an Insect Cytokine: Towards Understanding the Structural Basis for Development of EGFR Inhibitors for Cancer Treatment"
  • Samantha Gameros – Mentor: Erika Geisbrecht - "TRIM32-mediated regulation of glycolysis a new model for the Warburg effect in cancer"
  • Megan Goeckel (Microbiology) – Mentor: Gregory Finnigan - "Development of a molecular screening tool for new CRISPR variants for use in gene therapies"
  • Madelyn Hilgers – Mentor: Chingakham Singh (Biology) - "Transitional reprogramming during adeno-associated virus type 2 (AAV2) production through eIF5-mimic protein"
  • Isabel Lewis – Mentor: Gregory Finnigan - "Control of gene editing using novel anti-CRISPR proteins to the Cast12a nuclease"
  • Fawwaz Naeem (Biology) - Mentor: Erika Geisbrecht - "Identification of genes that function with Starvin/Bag3 to elucidate cancer-related functions"
  • Samuel Ockerhausen - Mentor: Jeroen Roelofs (Biology) - "Understanding the mislocalization of the proteasome, a cancer drug target, upon subunit truncation"
  • Seth Peery – Mentor: Kathrin Schrick (Biology) - "Origin of flavonoid anticancer compounds in charophycean green algae"
  • Robert Small – Mentor: John Tomich -"Interactions of Proteins with the outer leaflet of Branched Amphiphilic Peptide Capsules"

Presentations

Research and Exhibitions

  • Ho Leung Ng will be presenting a research poster on “Applying Artificial Intelligence Methods to Enhance Images from Crystallography and Microscopy” on July 28-Aug 3, 2018 at the Gordon Research Conference on Diffraction Methods in Structural Biology in Bates College in Lewiston, ME.
  • Erianna Basgall (undergrad, Finnigan) presented a poster, "Gene drive inhibition by the anti-CRISPR proteins AcrIIA2 and AcrIIA4 in Saccharomyces cerevisiae," June 24-26, 2018 at the National IDeA Symposium of Biomedical Research Excellence (NISBRE) conference in Washington D.C.
  • Gorman, M.J., Brummett, L.M., LeSuer, L.A., Weber, J.J. and Kanost. M.R. (2018) Characterization of Transferrin-1 from Drosophila melanogaster. American Society for Biochemistry and Molecular Biology Annual Meeting, San Diego. April 21-25, 2018
  • Li., M., Christen, J.M., Dittmer, N.T., Cao, X., Zhang, X., Jiang, H. and Kanost, M.R. (2018) Analysis of serpin genes and proteins in the tobacco hornworm. American Society for Biochemistry and Molecular Biology Annual Meeting, San Diego. April 21-25, 2018.
  • Anne Dykeman (undergrad, Davis) will present "Fatty Acid, Phospholipid and Sterol Composition of Salt Cedar (Tamarix spp.) Roots" at Undergraduate Research Day at the Capitol in Topeka on February 14. announcement
  • Timothy Durrett presented a poster, "Targeted metabolic engineering of Camelina sativa to synthesize high levels of industrially useful lipids," by Jose Aznar-Moreno, Linah Alkotami, Cathering Kornacki, Tam Tran-Nguyen, Shahna Campbell, and Timothy Durrett, on January 12 at the USDA-NIFA Annual Meeting in San Diego, CA.
  • Michal Zolkiewski presented a poster, "Interaction of Substrate-mimicking Peptides with the AAA+ Atpase ClpB from Escherichia coli," by Chathurange Ranaweera, Przemyslaw Glaza, and Michal Zolkiewski, on January 13 at the Midwest Stress Response and Molecular Chaperone Meeting in Evanston, IL.
  • Ho Leung Ng presented a poster, "Computational tools for discovering allosteric Ras inhibitors," December 6-8 at The Second RAS Initiative Symposium in Frederick, MD.

Publications