Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
Manhattan, KS 66506
785-532-6121
785-532-7278 fax
biochem@k-state.edu



Biotechnology Core Facility
206 Burt Hall
785-532-5956
785-532-6297 fax



Biomolecular NMR Facility
37 Chalmers Hall
785-532-2345

Recent Department Achievements

Faculty Achievements

Student Awards and Scholarships

  • Jenny Barriga (graduate, S. Bossmann) received a fellowship from Phi Kappa Phi in May 2014 Press Release
  • Nicole Green (graduate, E. Geisbrecht) is an NSF EIDRoP GK-12 Graduate fellow for 2014-2015.
  • Sara DuhachekMuggy  (graduate, Zolkiewska) and Pinakin Sukthankar (graduate, Tomich) received the 2014 Excellence in Biochemistry and Molecular Biophysics Graduate Research Award from the department.
  • Jessica Wheeler (undergraduate) and Weihong Zhang (graduate) were initiated into Phi Kappa Phi collegiate honor society on April 23, 2014. Press Release
  • Gillian Long was selected for 2014-2015 Mortar Board National Senior Honor Society, K-State chapter. April 16, 2014 Press Release
  • Adam J. Schieferecke selected for 2014-2015 Silver Key sophomore leadership honorary. April 7, 2014 Press Release
  • Obdulia Covarrubias Zambrano (undrergraduate, Rotenberg) received second place on her undergraduate student poster presentation at the K-State Research Forum March 26, 2014.
  • Thuy Cao (undergraduate, Kanost) was nominated for the 2014 Goldwater Scholarship. March 6, 2014 Press Release
  • Weihong Zhang (graduate, Chen) received the 2013 Excellence in Biochemistry and Molecular Biophysics Graduate Research Award from the department.
  • James Balthazor (graduate, Reeck) received the 2012-2013 Excellence in Biochemistry and Molecular Biophysics Graduate Teaching Award from the department.
  • Elizabeth Ploetz (2010 BS/MS graduate) Chosen to participate in the 63rd Lindau Nobel Laureate Meeting in Lindau, Germany, June 30 to July 5, 2013. Press Release
  • Obdulia Covarrubias (undergraduate, Tomich) named a 2013 McNair Scholar and member of Mortar Board, national senior honor society. Press Release
Fall 2013 K-State Johnson Cancer Center Undergraduate Cancer Research Awards

BMB undergraduate unless otherwise noted.

  • Susan Whitaker (Tomich) Tuning of a peptide capsule based system for timed drug delivery
  • Macy Garcia (Tomich) Alternative transfection protocol for anti-cancer vaccine vector against HPV-16
  • Jonathan Bernard (Biology, Tomich) Directed mutagenesis of Brevibacterium linens for the increased production of fermentation derived B-Cryptoxanthin
  • Michael Mohan (Chen) Effects of T-ALL mutations on mechanical activation of human NOTCH1 protein
  • Jamilah Watkins (Life Sciences, Kanost) Biochemical characterization of a serine protease inhibitor from the Kunitz family
  • Thuy Cao (Kanost) Structure and function of a metalloprotease with a potential role in degrading an extracellular matrix
  • Leiming Tang (Asano) Control of translation initiation stringency by elF5-mimic protein (5MP) during tumorigenesis
  • Cody Simmons (Clem) Characterizing expression of a growth factor gene and evaluating its potential role in virus infection
  • Jenny Barriga (Bossmann) Using non-pathogenic bacteria to deliver chemotherapeutic drugs to tumors
  • Madison Caywood (Bossmann) Measuring fluorescence levels of protease activity with different serum samples to find cancer progression markers in hopes of developing a new detection method for breast cancer

Presentations

June
  • Brian Geisbrecht presented an invited talk, “Selective Inhibition of Complement and Neutrophil Serine Protease Activity by a Family of Secreted Staphylococcal Immune Evasion Proteins”, at the 7th International Conference on Complement Therapeutics in Olympia, Greece on June 6-11, 2014.
  • Alex Beugelsdijk presented his MS. Defense, “Understanding amyloid fibril growth through theory and simulation”, June 17, 2014.
  • Beibei Li presented her MS. Defense, “Functional genomics and dynamic assembly of cuticular proteins ananlogous to peritrophin and knickkopf into the procuticle of Tribolium Castaneum”, June 25, 2014.
May
  • Matthew Aksamit presented his MS. defense, "Bioinformatic Analysis of Pea Aphid Salivary Gland Transcripts" on May 2, 2014.
  • Jarrod Bechard presented his MS. defense, "Armet Transcript Knockdown in Tribolium Castaneum", May 6, 2014.
April
  • Anna Zolkiewska, presented an invited talk “"Metalloprotease-Disintegrin ADAM12: a therapeutic potential in breast cancer.” Department of Biomedical Sciences Molecular Mechanisms of Carcinogenesis Program, Creighton University School of Medicine, Omaha, NE. April 8, 2014.
  • Rohit Babli Kamat presented his Ph.D. defense, "Phytoremediation for synthetic dye decolorization" on April 3, 2014.
March
  • Timothy Durrett, “From Burning Bushes to Chocolate Vines: Using Sequence Diversity to Explore MBOAT Substrate Specificity.” Presentation to the Biochemistry Department at the University of Missouri, March 7, 2014.
  • Zongheng Wang, Nicole Green, (graduate, E. Geisbrecht), Ze Liu, Catherine Rabouille, presented a platform presentation, “Clueless/dGRASP dependent unconventional protein secretion differentiates the delivery of αPS2 integrin from that of βPS integrin in the Drosophila muscle” at the GSA Drosophila Annual Conference in San Diego, CA, March 28, 2014.
February
  • Jianhan Chen co-chaired the 8th Intrinsically Disordered Protein Annual Symposium at the Biophysical Society 58th Annual Meeting in San Francisco, CA, February 14-19.
  • John Tomich, Sukthankar, P. Whitaker, S.K., Avila, L.A., Gao, J., Dadachova, E.. Peptide Nano-capsules with Lipid Vesicle-like Characteristics. Biophysical Society 58st Annual Meeting in San Francisco, CA, February 15-19.
  • Pinakin Sukthankar presented his Ph.D. defense, "Biophysical Characterization of Branched Amphiphilic Peptide Capsules and their Potential Applications in Radiotherapy" on February 25, 2014.

Research and Exhibitions

June
  • Luz Adriana Avila Flores (graduate, Tomich) presented a poster, “Branched amphiphilic peptide capsules: retention of encapsulated solutes and DNA vaccine delivery vehicles”, at the Drug Discovery & Therapy World Congress 2014, in Boston, MA on June 16-19, 2014.
  • Beibei Li (graduate, Muthukrishnan) presented a poster, “Dynamic assembly of cuticular proteins into the elytral procuticle of Tribolium castaneum”, at the Annual Arthropod Genomics Symposium in Urbana, IL on June 12-14, 2014.
  • Michael Kanost presented a poster, “Hemolymph serine proteases and protease inhibitors in the genome of Manduca sexta”, at the 8th Annual Arthropod Genomics Symposium in Urbana-Champaign, IL on June 12-14, 2014.

April
  • Sunil Bansal (graduate, Durrett) and Timothy Durrett gave a poster presentation, "Generation of Reduced Viscosity Plant Oils Using an Unusual Acyltransferase: A Step Towards Sustainable Production of an Advanced Biofuel" at the KSU Center for Sustainable Energy 2014 Energy Symposium on April 9-10, 2014.
  • Watkins, J., Takahashi, D., Hiromasa, Y., Kanost, M.R. (2014) “Identification and biochemical characterization of a Kunitz-type serine protease inhibitor from an insect, Manduca sexta.” American Society for Biochemsitry and Molecular Biology Annual Meeting, San Diego, CA on April 28, 2014.
  • Alsouhail, Q., Hiromasa, Y., and Kanost, M.R. (2014) “Identification of an antifungal peptide from hemolymph of an insect, Manduca sexta.” American Society for Biochemsitry and Molecular Biology Annual Meeting, San Diego, CA on April 29, 2014.
  • Daisuke Takahashi (postdoc, Kanost) gave a poster presentation, “Protein self-association of N-terminal domain of β-1,3-glucan recognition protein upon binding to β-1,3-glucan stimulates the prophenoloxidase activation in Manduca” at the 2014 Annual Meeting of the American Society for Biochemistry and Molecular Biology in San Diego, CA on April 25-30, 2014.
  • Lorne Jordan (graduate, Klebba) presented a poster, “Concerted Loop Motion Triggers Induced Fit of FepA to Ferric Enterobactin”, at the Experimental Biology National Conference in San Diego, CA on April 30, 2014.
2014 K-State Developing Scholars 14th annual Research Poster Symposium

BMB undergraduate unless otherwise noted.

  • Jenny Barriga (Chemistry and Biochemistry, Bossman) presented "Cell-Based Delivery of Chemotherapeutics and Antibiotics"
  • Jonathan Bernard (Biology, Tomich) presented "The Extraction of Forskolin to Increase Cost Efficiency"
  • Thuy Cao (Dittmer) presented "ACE-like Enzyme in Insect Molting Fluid"
  • Thuan Daniel Quach (Weiss) presented "The Effect of Type of Collection Medium and Freezing Extender on Rat Sperm Cryosurvival Rate"
  • Larry Rodriguez (Marshall) presented "The Chemistry of Sex Games: Why Do Male Crickets Transfer Large Amounts of Dopamine to Females During Copulation?"
  • Jamilah B. Watkins (Life Sciences, Kanost) presented "Identification and Biochemical Characterization of a Kunitz-Type Serine Protease Inhibitor From an Insect, Manduca Sexta"
  • Obdulia Covarrubias Zambrano (Rotenberg) presented "Investigating the Effects of Elevated Temperature on Tomato Spotted Wilt Virus Accumulation and Expression of Putative Heat-Shock Protein Genes in the Insect Vector, Frankliniella Occidentalis"
  • Mauri Zumalt (Davis) presented "Degradation of Textile Dyes in Miscanthus Sinesis."
March
  • Nicole Green (graduate, E. Geisbrecht), Nadia Odell, Clara Bazjek, Shufei Zhuang, Mitch Dushay, presented a poster, “Fondue and Tiggrin Interact at Muscle-Muscle Attachments”, at the GSA Drosophila Annual Conference in San Diego, CA, March 26-30, 2014.
  • Bridget H. Biersmith (graduate, E. Geisbrecht) presented a poster, “Differential Roles of Dock Family Members in Development”, at the GSA Drosophila Annual Conference in San Diego, CA, March 27, 2014.
February
  • Weihong Zhang (graduate, Chen) presented a poster, “Accelerate Sampling in Atomistic Energy Landscapes Using Topology-Based Coarse-Grained Models,” at the CCP-SAS Kickoff Workshop, NIST Center for Neutron Research, February 7-9.
  • Weihong Zhang (graduate, Chen) presented a poster, “Accelerate Sampling in Atomistic Energy Landscapes Using Topology-based Coarse-grained Models,” at the Biophysical Society 58th Annual Meeting in San Francisco, CA, February 14-19.
January
  • Fabrice Ngansop, Hui Li, Anna Zolkiewska, and Michal Zolkiewski presented a poster, "Biochemical characterization of the apicoplast-targeted AAA+ATPase ClpB from Plasmodium falciparum," at the 19th Annual Midwest Stress Response and Molecular Chaperone Meeting, Northwestern University, Evanston, IL on January 18, 2014
  • Jamilah Watkins, Daisuke Takahashi, Yasuaki Hiromasa, and Michael Kanost presented a poster, "Identification and Biochemical characterization of a Kunitz-type serine protease inhibitor from a insect, Manduca sexta," at the 12th Annual K-INBRE Symposium, Kansas City, MO, on January 17-19, 2014.
  • Beibei Li (grad, Muthukrishnan) presented a poster, "Dynamic assembly of cuticular proteins into the elytral procuticle of Tribolium castaneum," at the 12th Annual K-INBRE Symposium, Kansas City, MO, on January
    17-19, 2014.
  • Weihang Zhang and Jianhan Chen presented a poster, "Accelerate sampling in atomistic energy landscapes using topology-based coarse-grained models," GRC-Protein Folding and Dynamics, in Galveston, TX, on January 5-10, 2014.
December
  • Yue Qi (grad, Zolkiewska) and Hui Li (postdoc, Zolkiewska) presented a poster, “Functional characterization of three novel breast cancer-related somatic mutations in metalloproteinase-disintegrin ADAM12,” at San Antonio Breast Cancer Symposium, in San Antonio, TX, December 10-14, 2013.

Publications

May
April
March
February
January
  • Pidlisnyuk, V., Stefanovaska, T., Lewis, E.E., Erickson, L.E., and Davis, L.C. (2014), Miscanthus as a Productive Biofuel Crop for Phytoremediation. Critical Reviews in Plant Sciences 33:1, 1-19, DOI:10.1080/07352689.2014.847 616
  • Takahashi, D., Kim, Y., Lovell, S., Prakash, O., Groutas, W., and Chang, K. (2013). Structural and inhibitor studies of norovirus 3C-like proteases. Virus Research: Vol. 178: 437-444 PubMed ID: 24055466

Travel awards

June
  • Alvaro Herrera (graduate, Prakash) received an Arts & Sciences Graduate Student Research Travel Award to present a poster, “Structural Determinants of Host Defense Peptide Fowlicidin-2 for Antimicrobial Potency and Target Cell Selectivity”, at the International Conference on Magnetic Resonance in Biological Systems in Dallas, TX on August 24-29, 2014.

May
  • Luz Adriana Avila Flores (graduate, Tomich) received the Hageman Graduate Travel award to present a poster, "Branched amphiphilic peptide capsules: retention of encapsulated solutes and DNA vaccine delivery vehicles”, at the Drug Discovery & Therapy World Congress 2014, in Boston, MA. on June 16-19, 2014.
  • Aashima Khosla (graduate, Schrick) received a Johnson Cancer Center travel award and a Hageman Graduate travel award to give an oral presentation, “Interaction between GL2, HDG11 and MYB23 in maintenance of trichome cell fate”, at the 25th International Conference on Arabidopsis Research in Vancouver, Canada on July 28 – August 1, 2014.
April
  • Obdulia Covarrubias Zambrano (senior, Rotenberg) received second place in undergraduate student poster presentation session one at the K-State Research Forum March 26, 2014.
  • Daisuke Takahashi (postdoc, Kanost) received an ASBMB Postdoctoral and Graduate Travel Award to present a poster, “Protein self-association of N-terminal domain of β-1,3-glucan recognition protein upon binding to β-1,3-glucan stimulates the prophenoloxidase activation in Manduca”, at the 2014 Annual Meeting of the American Society for Biochemistry and Molecular Biology in San Diego, CA on April 25-30, 2014.
  • Lorne Jordan (graduate, Klebba) received the KSU College of Arts and Sciences Award, the Graduate Student Council Travel Award, and the Hageman Graduate Student Travel Award present a poster, “Concerted Loop Motion Triggers Induced Fit of FepA to Ferric Enterobactin”, and attend the Experimental Biology National Conference in San Diego, CA from April 26-30, 2014.
March
  • Sara Duhachek-Muggy (graduate, A. Zolkiewska) received the Alvin and RosaLee Sarachek Predoctoral Honors Travel Award, 2014.
  • Nicole Green (graduate, E. Geisbrecht) received the KSU College of Arts and Sciences Award and the Hageman Graduate Student Travel Award for a poster presentation, “Fondue and Tiggrin Interact at Muscle-Muscle Attachments”, at the GSA Drosophila Annual Conference in San Diego, CA, March 26-30, 2014.
February
  • Weihong Zhang (graduate, Chen) received a Johnson Cancer Center Graduate Student and Postdoctoral Travel Award to present a poster at the Biophysical Society 58th Annual Meeting in San Francisco, CA, February 15-18.