Subbaratnam Muthukrishnan, University Distinguished Professor Emeritus
Complete publications list
1960s | 1970s | 1980s | 1990s | 2000s | 2010s | 2020s | Books edited | Journals edited | Patents issued
1960s
Padmanabhan, G., Muthukrishnan, S., and Sarma, PS. (1967) The role of iron in heme synthesis in Neurospora crassa. Biochem. Biophys. Acta, 141:187-190.
Muthukrishnan, S., Padmanabhan, G., and Sarma, PS. (1968) Role of iron in the regulation of heme biosynthesis in N. crassa. Biochem. Biophys. Res. Commun., 31:333-339.
Padmanabhan, G., Muthukrishnan, S., Subramanian, KN., and Sarma, PS. (1968) The in vivo donor for heme synthesis in Neurospora crassa. Indian J. Biochem., 5:153-156.
Muthukrishnan, S., Padmanabhan, G., and Sarma, PS. (1969) Regulation of heme biosynthesis in Neurospora crassa. J. Biol. Chem., 244:4241-4246.
1970s
Rao, MRS., Padmanabhan, G., Muthukrishnan, S., and Sarma, PS. (1970) Feedback inhibition of delta-aminolevulinate dehydratase by coproporphyrinogen III. Indian J. Biochem., 7:132-133.
Muthukrishnan, S. (1971) Replication of single-stranded viral RNA. J. Sci. Ind. Res., 30:28-38.
Muthukrishnan, S., Malathi, K., and Padmanabhan, G. (1972) delta-Aminolevulinate dehydratase-regulatory enzyme of the heme biosynthetic pathway in Neurospora crassa. Biochem. J., 129:31-37.
Rothman-Denes, LB., Muthukrishnan, S., Haselkorn, R., and Studier, W. (1972) A T7 gene shuts off host and early viral transcription. Virus Research, Academic Press, 227-239.
Muthukrishnan, S. and Shatkin, AJ. (1975) Reovirus genome RNA segments: Resistance to S1 Nuclease. Virology, 64:96-105.
Furuichi, Y., Morgan, M., Muthukrishnan, S., and Shatkin, AJ. (1975) Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: 7mG5 ppp5 GMP Cp. Proc. Natl. Acad. Sci. USA., 72:362-366.
Furuichi, Y., Muthukrishnan, S., and Shatkin, AJ. (1975) 5'-terminal 7mG5 ppp5' Gmp in vivo: Identification in reovirus genome RNA. Proc. Natl. Acad. Sci. USA., 72:742-745.
Muthukrishnan, S., Both, GW., Furuichi, Y., and Shatkin, AJ. (1975) 5'-terminal 7-Methylguanosine in eukaryotic mRNA is required for translation. Nature, 255:33-37.
Both, GW., Furuichi, Y., Muthukrishnan, S., and Shatkin, AJ. (1975) Ribosome binding to mRNA in protein synthesis requires 5'-terminal 7-methylguanosine. Cell, 6:185-195.
Shatkin, AJ., Banerjee, AK., Both, GW., Furuichi, Y., and Muthukrishnan, S. (1975) 5'-terminal 7-methylguanosine in eukaryotic mRNAs in its requirement for translation. EMBO Workshop on "In Vitro Transcription and Translation," Thivernal, France, Vol. 255:33-37.
Muthukrishnan, S., Filipowicz, W., Sierra, JM., Both, GW., Shatkin, AJ., and Ochoa, S. (1975) mRNA methylation and protein synthesis in extracts from embryos of brine shrimp, Artemia Saline. J. Biol. Chem., 250:9336-9341.
Shatkin, AJ., Banerjee, AK., Both, GW., Furuichi, Y., and Muthukrishnan, S. (1976) Dependence of translation of 5'-terminal methylation of mRNA. Fed. Proc., 35:2214-2217.
Both, G. W., Furuichi, Y., Muthukrishnan, S., and Shatkin, AJ. (1976) Effect of 5'-terminal structure and base composition on polyribonucleotide binding to ribosomes. J. Mol. Biol., 104:637-658.
Furuichi, Y., Muthukrishnan, S., Tomasz, J., and Shatkin, AJ. (1976) Mechanism of formation of reovirus mRNA 5'-terminal blocked and methylated sequence, m7GpppGmpC. J. Biol. Chem., 251:5043-5053.
Shatkin, AJ., Both, GW., Furuichi, Y., Kozak, M., and Muthukrishnan, S. (1976) 5'-Terminal 7-methylguanosine in viral mRNAs and its role in translation. In "Animal Virology" (ICN-UCLA Symposia on Molecular and Cellular Biology). Eds: D. Baltimore, AS. Huang, CF. Fox. pp. 659-676.
Filipowicz, W., Furuichi, Y., Sierra, JM., Muthukrishnan, S., Shatkin, AJ., and Ochoa, S. (1976) A protein binding the methylated 5'-terminal cap, m7GpppN, of eukaryotic messenger RNA. Proc. Natl. Acad. Sci. USA., 73:1559-1563.
Furuichi, Y., Muthukrishnan, S., Tomasz, J., and Shatkin, AJ. (1976) Caps in Eukaryotic mRNAs: Mechanisms of formation of reovirus mRNA 5'-terminal m7GpppGmpC. Prog. Nucl. Acid Res. and Mol. Biol., 19:3-20.
Muthukrishnan, S., Furuichi, Y., Both, GW., and Shatkin, AJ. (1976) Effect of 5'-terminal structures on the binding of ribopolymers to eukaryotic ribosomes. Prog. Nucl. Acid Res. and Mol. Biol., 19:473-476.
Muthukrishnan, S., Morgan, J., Banerjee, AK., and Shatkin, AJ. (1976) Influence of 5'-terminal m7G and 2-0-methylated residues on mRNA binding to ribosomes. Biochemistry, 15:5761-5768.
Muthukrishnan, S., Moss, B., Cooper, JA. and Maxwell, ES. (1978) Influence of 5'-terminal cap structure on the initiation of translation of vaccinia virus mRNA. J. Biol. Chem., 253:1710-1715.
Adams, BL., Morgan, M., Muthukrishnan, S., Hecht, SM. and Shatkin, AJ. (1978) The effect of Cap analogs on reovirus mRNA binding to wheat germ ribosomes. J. Biol. Chem., 253:2589-2596.
Keith, JM., Muthukrishnan, S. and Moss, B. (1978) Effect of methylation of the N6 position of the penultimate adenosine of capped mRNA on ribosome binding. J. Biol. Chem., 253:5039-5041.
Wodnar-Filipowicz, A., Szczesna, E., Zan-Kowalczewska, M., Muthukrishnan, S., Szybiak, U., Legocki, AB., and Filipowicz, W. (1978) 5'-Terminal 7-methylguanosine and mRNA function. Eur. J. Biochem., 92:69-80.
Chandra, GR., Muthukrishnan, S. and Maxwell, ES. (1979) Hormonal regulation of genome activity in higher plants. In "Plant Growth Substances" (ACS Symposium Series III) (Mandava, N. B., Ed.), pp. 245-261.
Muthukrishnan, S., Maxwell, ES. and Chandra, GR. (1979) Hormone-induced increase in the levels of functional mRNA and alpha-amylase mRNA in barley aleurones. Proc. Natl. Acad. Sci. USA., 76:6181-6185.
1980s
Muthukrishnan, S. (1982) mRNA methylation in plants. In "Biochemistry of S-adenosylmethionine and Related Compounds" (Usdin, E., Borchardt, R., and Creweling, R., Eds.), MacMillan Press, pp. 329-338.
Muthukrishnan, S., and Chandra, GR. (1983) Expressions of alpha-amylase genes in barley aleurone cells. Beltsville Symposia on Agricultural Research, 7:151-159.
Muthukrishnan, S., Chandra, GR., and Maxwell, ES. (1983) Hormonal control of alpha-amylase gene expression in barley--studies using a cloned cDNA probe. J. Biol. Chem., 258:2370-2375.
Muthukrishnan, S., Chandra, GR., and Albaugh, GP. (1983) Modulation by abscisic acid and S-2-aminoethyl-L-cysteine of alpha-amylase mRNA in barley aleurone cells. Plant Molec. Biol., 2:249-258.
Huang, J.-K., Swegle, M., Dandekar, A., and Muthukrishnan, S. (1984) Expression and regulation of α-amylase gene family in barley aleurones. J. Molec. Appl. Genet., 2:579-588.
Muthukrishnan, S., Gill, BS., and Chandra, GR. (1984) Structural genes for α-amylases are located on barley chromosomes 1 and 6. J. Biol. Chem., 259:13637-640.
Chandra, GR., Albaugh, GP., and Muthukrishnan, S. (1985) Methodology for gene expression. CRC Handbook of Naturally Occurring Pesticides. Vol. II (ed. Mandava, N. B.) CRC Press, Boca Raton, pp. 493-523.
Kumar, S., Chandra, GR., Albaugh, GP., and Muthukrishnan, S. (1985) Regulation of the expression of alpha-amylase genes by sodium butyrate. Plant Molec. Biol., 5:269-279.
Kalinski, A., Chandra, GR., and Muthukrishnan, S. (1986) Study of barley endonucleases and alpha-amylase genes. J. Biol. Chem., 261:11393-11397.
Knox, CAP., Sonthayanon, B., Chandra, GR., and Muthukrishnan, S. (1987) Structure and organization of two divergent alpha-amylase genes from barley. Plant Molecular Biology, 9:3-17.
Wang, CSW., Shastri, K., Wen, L., Huang, J-K., Sonthayanon, B., Muthukrishnan, S., and Reeck, GR. (1987) Heterogeneity in cDNA clones encoding rice glutelin. FEBS Letters, 222:135-138.
Muthukrishnan, S., and Chandra, GR. (1988) Regulation of the expression of hydrolase genes in cereals. Advances in Cereal Science and Technology (ed. by Y. Pomeranz) Vol. IX: 129-159.
Rahmatullah, RJ., Huang, J-K., Clark, KL., Reeck, GR., Chandra, GR., and Muthukrishnan, S. (1989) Nucleotide and predicted amino acid sequences of two different genes for high pI alpha-amylases from barley. Plant Molec Biol., 12:119-121.
Lee, SH., Muthukrishnan, S., Sorensen, EL., and Liang GH. (1989) Restriction endonuclease analysis of mitochondrial DNA from sorghum with fertile and male-sterile cytoplasms. Theoretical and Applied Genetics, 77:379-382.
Kam-Morgan, l., Gill, BS., and Muthukrishnan, S. (1989) DNA restriction fragment length polymorphisms: a strategy for rapid genetic mapping of the polyploid genome of wheat. Genome, 32:724-732.
Swegle, MS., Huang, JK., Lee, G., and Muthukrishnan, S. (1989) Identification of an endochitinase cDNA clone from barley aleurone cells. Plant Molecular Biol., 12:403-412.
1990s
Feng, GH., Wen, L., Huang, J-K., Shorrosh, BS., Muthukrishnan, S., and Reeck, GR. (1990). Nucleotide sequence of a cloned rice genomic DNA fragment that encodes a 10 kDA prolamin polypeptide. Nuc. Acids Res., 18:683.
Chen, Z., Liang, GH., Muthukrishnan, S., and Kofoid, KD. (1990) Chloroplast DNA polymorphism in fertile and male-sterile cytoplasms of sorghum (Sorghum bicolor (L.) Moench). Theor Appl. Genet., 80:727-731.
Lee, G., Sonthayanon, B., Huang, J-K., Chandra, GR., and Muthukrishnan, S. (1990) Regulation of barley alpha-amylase genes by abscisic acid. Proceedings of the International Congress of Plant Physiology. S.K. Sinha, PV. Sanw, SC. Bhargava, PK. Agrawal eds. Vedams Books International, New Delhi. Vol 2:795-799.
Chandra GR., Kalinski, S., and Muthukrishnan S. (1990) Gibberellins modulate plant genome activity. Proceedings of the International Congress of Plant Physiology. S. K. Sinha, P.V. Sanw, S.C. Bhargava, P.K. Agrawal eds. Vedams Books International, New Delhi. Vol 2:715-720.
Gopalakrishnan, B., Sonthayanon, B., Rahmatullah, R., and Muthukrishnan, S. (1991) Barley aleurone layer cell protoplasts as a transient expression system. Plant Molec. Biol., 16:463-467.
Corpuz, LM., Choi, H., Muthukrishnan, S., and Kramer KJ. (1991) Sequence and expression of two cDNA clones encoding methionine-rich storage proteins of Manduca sexta. Insect Biochemistry, 21:265-276.
Huang, J-K., Wen, L., Swegle, M., Tran, H-C., Thin, TH., Naylor, HM., Muthukrishnan, S., and Reeck, GR. (1991) Nucleotide sequence of a rice genomic clone that encodes a class I endochitinase Plant Molec. Biol., 16:479-480.
Wen, L., Huang, J-K., Zen, K-C., Johnson, BH., Muthukrishnan, S., MacKay, V., Manney TR., Manney M., and Reeck, GR. (1992) Nucleotide sequence of a cDNA clone that encodes the maize inhibitor of trypsin and activated Hageman factor. Plant Molec Biol., 18:813-814.
Sharrosh, BS., Wen, L., Zen, KC., Huang J-K., Pan JS., Hermodson, MA., Tanaka, K., Muthukrishnan, S., and Reeck, GR. (1992) A novel cereal storage protein: molecular genetics of the 19 kDa globulin of rice. Plant Molecular Biology, 18:151-154.
Anuratha, CS., Huang, J-K., Pingali, A., and Muthukrishnan, S. (1992) Isolation and characterization of a chitinase and its cDNA clone from rice. J. Plant Biochem. & Biotech., Vol. 3:91-95.
Chen, MS., Johnson, B., Wen, L., Muthukrishnan, S., Kramer, KJ., Morgan, TD., and Reeck, GR. (1992) Rice cystatin: Bacterial expression, purification, cysteine proteinase inhibitory activity and insect growth suppressing activity of a truncated form of the protein. Protein Expression and Purification, 3:41-49
Koga D., Funakoshi T., Mizuki K., Ide A., Kramer KJ., Zen KC., Choi H., and Muthukrishnan S. (1992) Immunoblot analysis of chitinolytic enzymes in integument and molting fluid of the silkworm, Bombyx mori and the tobacco hornworm, Manduca sexta. Insect Biochem Mol Biol., 22:305-311.
Swegle, M., Kramer, KJ., and Muthukrishnan, S. (1992) Properties of barley seed chitinases and release of embryo-associated isoforms during early stages of imbibition. Plant Physiology, 99:1009-1014
Chen Z., Muthukrishnan S., Liang GH., Schertz KF., and Hart GE. (1993) CMS-associated chloroplast DNA deletion located in RNA polymerase gene rpoC2 in sorghum. Molecular and General Genet, 236:251-259.
Darnetty, Leslie, JF., Muthukrishnan, S., Swegle, M., Vigers, AJ., and Selitrennikoff, CP. (1993) Variability in antifungal proteins in the grains of maize, sorghum and wheat. Physiologia Plantarum, 88:339-349.
Kramer, KJ., Corpuz, L., Choi, HK., and Muthukrishnan, S. (1993) Sequence of a cDNA and expression of the gene encoding epidermal and gut chitinases of Manduca sexta. Insect Biochem Molec Biol., 23:691-701.
Shu, G., Muthukrishnan, S., Liang, GH., and Paulsen, G. (1993) Restriction fragment patterns of chloroplast and mitochondrial DNA of Daspyrum villosum (L.) candargy and wheats. Theoretical and Applied Genetics, 87:44-48.
Ignatius, MJS., Chopra, RK., and Muthukrishnan, S. (1994) Effects of fungal infection and wounding on the expression of chitinases and beta-1,3-glucanases in near-isogenic lines of barley. Physiologia Plantarum, 90:584-592.
Ignatius, MJS., Huang J-K., Chopra, RK., and Muthukrishnan, S. (1994) Isolation and characterization of a barley chitinase genomic clone- Expression in powdery-mildew infected barley. J Plant Bioch & Biotech., 3:91-95.
Gopalakrishnan, B., Muthukrishnan, S., and Kramer, KJ. (1995) Baculovirus-mediated expression of a Manduca sexta chitinase gene: Properties of the recombinant protein. Insect Bioch Mol Biol., 25:255-265.
Lin, W., Anuratha, CS., Datta, K., Potrykus, I., Muthukrishnan, S., and Datta, SK. (1995) Genetic engineering of rice for resistance to sheath blight. Bio/Technology, 13:686-691.
Anuratha, CS., Zen, KC., Cole, KC., Mew, T., and Muthukrishnan, S. (1996) Induction of chitinases and beta-glucanases in Rhizoctonia solani-infected rice plants: Isolation of an infection-related chitinase cDNA clone. Physiologia Plantarum, 97:39-46.
Zen, KC., Choi, HK., Nandigama, K., Muthukrishnan, S. and Kramer, KJ. (1996) Cloning, expression and hormonal regulation of an insect beta-N-acetylglucosaminidase gene. Insect Biochem. Molec. Biol., 26:435-444.
Lin, W., Gopalakrishnan, B., and Muthukrishnan, S. (1996) Transcription efficiency and hormone-responsiveness of alpha-amylase gene promoters in an improved transient expression system from barley aleurone protoplasts. Protoplasma, 192:93-108.
Wang, X., Ding, X., Gopalakrishnan, B., Morgan, TD., Johnson, LB., White, FF., and Kramer, KJ. (1996) Characterization of a 46 kDa insect chitinase from transgenic tobacco. Insect Biochem. Molec. Biol., 26:1055-1064.
Choi, HK., Choi, KH., Kramer, KJ., and Muthukrishnan, S. (1997) Isolation and characterization of a genomic clone for the gene of an insect molting enzyme, chitinase. Insect Biochem. Molec. Biol., 27:37-47.
Kramer, KJ., Muthukrishnan, S., Johnson, LB., and White, F. (1997) Chitinases for insect control. In: Transgenic Plants for Control of Insect Pests. (N. Carozzi and M. Koziel, eds.), Taylor and Francis Publ., Washington, D. C. pp.185-193.
Vidhyasekaran, P., Ponmalar, TR., Samiyappan, R., Velazhzhan, R., Vimala, R., Ramanathan, A., Paranidharan, V., and Muthukrishnan, S. (1997) Host-specific toxin production by Rhizoctonia solani, the rice sheath blight pathogen. Phytopathology, 87:1258-1263.
Sriram, S., Raghuchander T., Vidhyasekaran, P., Muthukrishnan, S., and Samiyappan, R. (1997) Genetic relatedness with special reference to viruelence among the isolates of Rhizoctonia solani causing sheath blight in rice. J. Plant Diseases & Protection, 104:260-271.
Kramer, KJ. and Muthukrishnan, S. (1997) Insect Chitinases:Molecular biology and potential use as biopesticides. Insect Biochem Molec. Biol., 27:887-900.
Liang, G., Skinner, DZ., and Muthukrishnan, S. (1997) Crop improvement using microprojectile bombardment and Agrobacterium-mediated transformation. Trends in Agronomy, 1:57-73.
Ding X., Gopalakrishnan, B., Johnson, L., White FF., Wang, X., Morgan, TD., Kramer, KJ., and Muthukrishnan, S. (1998) Insect resistance of transgenic tobacco expressing an insect chitinase gene. Transgenic Research, 7:77-84.
Velazhahan, R., Chen-Cole, K., Anuratha, CS., and Muthukrishnan, S. (1998) Induction of thaumatin-like proteins (TLPs) in Rhizoctonia solani-infected rice and characterization of two new cDNA clones. Physiologia Plantarum, 102:21-28.
Hazeg-Azam, M., Kim, S., Masoud, S., Andersson, L., White, F., Johnson, L., Muthukrishnan, S., and Reeck, G. (1998) The corn inhibitor of activated Hagemen factor: Purification and properties of two recombinant forms of the protein. Protein Expression and Purification, 13:143-149.
Chen, WP., Chen, PD., Liu, DJ., Muthukrishnan, S., and Gill, BS. (1998) Constitutive expression a rice thaumatin-like protein gene in T0, T1, and T2 transgenic wheat plants. In: Proceedings of the 9th International Wheat Genetics Symposium, ed. A. E. Slinkarol, Vol. 3, 169-171.
Zhu, H., Krishnaveni, S., Liang, GH., and Muthukrishnan, S. (1998) Biolistic transformation of sorghum using a rice chitinase gene. J. Genet. Breed, 52:243-252.
Chen, WP., Gu, X., Liang, GH., Muthukrishnan, S., Chen, PD., Liu, DJ., and Gill, BS. (1998) Introduction and constitutive expression of a rice chitinase gene in bread wheat using biolistic bombardment and the bar gene as a selectable marker. Theor. Appl. Genet, 97:1296-1306.
Chareonpornwattana, S., Thara, KV., Wang, L., Datta, SK., Panbangred, W., and Muthukrishnan, S. (1999) Inheritance, expression, and silencing of a chitinase transgene in rice. Theor. Appl. Genet, 98:371-378.
Datta, K., Velazhahan, R., Oliva, N., Mew, T., Muthukrishnan, S., and Datta, SK. (1999) Over-expression of the cloned rice thaumatin-like protein (PR-5) gene in transgenic rice plants enhances environmentally friendly resistance to Rhizoctonia solani causing sheath blight disease. Theor. Appl. Genet, 98:1138-1145.
Velazhahan, R., Datta, SK., and Muthukrishnan, S. (1999) The PR-5 family; Thaumatin-like Proteins. In: Pathogenesis-Related Proteins in Plants. Ed. S. K. Datta and S. Muthukrishnan, CRC Press, Boca Raton, FL . ISBN:0-8493-0697, 107-129
Datta, K., Muthukrishnan, S., and Datta, SK. (1999) Expression and function of PR-protein genes in transgenic plants. In: Pathogenesis-Related Proteins in Plants. Ed. S. K. Datta and S. Muthukrishnan, CRC Press, Boca Raton, FL . ISBN:0-8493-0697, 261-277.
Krishnaveni, S., Liang, GH., Muthukrishnan, S., and Manickam, A. (1999) Purification and partial characterization of chitinases from sorghum seeds. Plant Science, 144:1-7.
Krishnaveni, S., Muthukrishnan, S., Liang, GH., Wilde, G., and Manickam, A. (1999) Induction of chitinases and beta-1,3-glucanases in resistant and sensitive cultivars of sorghum in response to insect attack, fungal infection and wounding. Plant Science, 144:9-16.
Chen, WP., Chen, PD., Liu, DJ., Kynast, RJ., Friebe, B., Velazhahan, R., Muthukrishnan, S., and Gill, BS. (1999) Development of wheat scab symptoms is delayed in transgenic wheat plants that constitutively express a rice thaumatin-like protein gene. Theor. Appl. Genet, 99:755-760.
2000s
Huang, X., Zhang, H., Zen, KC., Muthukrishnan, S., and Kramer, KJ. (2000) Homology modeling of the insect chitinase catalytic domain-oligosaccharide complex and the role of a putative active site tryptophan in catalysis. Insect Biochem. Molec. Biol., 30:107-117.
Yu, TT., Skinner, DZ., Liang, GH., Trick, HN., and Muthukrishnan, S. (2000) Agrobacterium-mediated transformation of creeping bentgrass using GFP as reporter gene. Hereditas, 133:229-233.
Li, WL., Faris, JD., Muthukrishnan, S., Liu, DJ., Chen, PD., and Gill, BS. (2001) Isolation and characterization of novel cDNA clones of acidic chitinases and beta-1,3-glucanases from wheat spikes infected by Fusarium graminearum. Theor. Appl. Genet, 102:353-362.
Datta, K., Tu, JM., Oliva, N., Ona, I., Velazhahan, R., Mew, TW., Muthukrishnan, S., and Datta, SK. (2001) Enhanced resistance to sheath blight by constitutive expression of infection-related rice chitinase in transgenic elite Indica rice cultivars. Plant Sci., 160:405-414.
Muthukrishnan, S., Liang, GH., Trick, HN., and Gill, BS. (2001) Pathogenesis-related proteins and their genes in cereals. Plant Cell, Tissue and Organ Culture, 64:93-114.
Jackson, SA., Zhang, P., Chen, W., Phillips, RL., Friebe, B., Muthukrishnan, S., and Gill, BS. (2001) High resolution structural analysis of biolistic transgene integration into nuclear genome of wheat. Theor. Appl. Genet, 103:56-62.
Velazhahan, R., Radhajeyalakshmi, R., Thangavelu, R., and Muthukrishnan, S. (2001) An antifungal protein purified from pearl millet seeds shows sequence homology to lipid transfer proteins. Biologia Plantarum, 43(3):417-421.
Zhu, X., Zhang, H., Fukamizo, T., Muthukrishnan, S., and Kramer, KJ. (2001) Properties of Manduca sexta Chitinase and its C-Terminal Deletions. Insect Biochem. Molec. Biol., 31:1221-1230.
Waniska, RD., Venkatesha, RV., Chandrashekar, A., Krishnaveni, S., Bejosano, FP., Jeoung, J., Jayaraj, J., Muthukrishnan, S., and Liang, GH. (2001) Antifungal proteins and other mechanisms in the control of sorghum stalk rot and grain mold. J. Agric. Food. Chem., 49:4732-4742.
Muthukrishnan, S., Kramer, KJ., Zhang, H., Lu, Y., Matsumiya, M., and Anand, A. (2001) Use of chitinases as Biopesticides. In: Chitin and Chitosan - Chitin and Chitosan in Life Science (ed. T. Uragami, K. Kurita & T. Fukamizo). Kodansha Scientific Ltd., ISBN 4-906464-13-0. pp. 415-418
Velazhahan, R., Zen, KC., and Muthukrishnan, S. (2001) Expression of a rice thaumatin-like protein (PR-5) gene in a baculovirus expression system. Acta Phytopathologica et Entomologica Hungarica, 36:311-316.
Krishnaveni, S., Jeoung, J-M., Muthukrishnan, S., and Liang, GH. (2001) Transgenic sorghum plants constitutively expressing a rice chitinase gene show improved resistance to stalk rot. J. Genet. & Breeding 55:151-158.
Thangavelu, R., Palaniswami, A., Ramakrishnan, G., Doraiswami, S., Muthukrishnan, S., and Velazhahan, R. (2001) Involvement of fusaric acid detoxification by Pseudomonas fluorescens strain Pf10 in the biological control of Fusarium wilt of banana caused by Fusarium oxysporum f. sp. cubense. J. Plant Disease and Protection, 108:433-445.
Zhu, Y-C., Muthukrishnan, S., and Kramer, KJ. (2002) cDNA sequences and mRNA levels of two hexamerin storage proteins pinSP1 and PinSP2 from the Indianmeal moth Plodia interpunctella. Insect Biochem. Molec. Biol., 32:525-536.
Sakthivel, N., Amudha, R., and Muthukrishnan, S. (2002) Production of cytotoxic metabolites by Sarocladium oryzae. Mycological Research, 106:5:609-614.
Zhu, Y-C., Specht, CA., Dittmer, N., Muthukrishnan, S., Kanost, MR., and Kramer, KJ. (2002) Sequence of a cDNA and Expression of the Gene Encoding a Putative Epidermal Chitin Synthase of Manduca sexta. Insect Biochem. Mol. Biol., 32:1497-1506.
Lu, Y., Zen, K-C., Muthukrishnan, S., and Kramer, KJ. (2002) Site-directed mutagenesis and functional analysis of active site acidic amino acid residues D142, D144, and E146 in Manduca sexta (tobacco hornworm) chitinase. Insect Biochemistry and Molecular Biology, 32:1369-1382.
Zhang, H., Huang, X., Fukamizo, T., Muthukrishnan, S., and Kramer, KJ. (2002) Site-directed mutagenesis and functional analysis of an active site tryptophan of insect chitinase. Insect Biochemistry and Molecular Biology, 32:1477-1488.
Velazhahan, R., Jayaraj, J., Jeoung, J-M., Liang, GH., and Muthukrishnan, S. (2002) Purification and characterization of an antifungal thaumatin-like protein from sorghum leaves. J. Plant Diseases & Protection, 109:452-461.
Jeoung, JM., Krishnaveni, S., Muthukrishnan, S., Trick, HN., and Liang, GH. (2002) Optimization of sorghum transformation parameters using genes for green fluorescent protein and β-glucuronidase as visual markers. Hereditas, 137:20-28
Anand, A., Zhou, T., Trick, HN., Gill, BS., Bockus, WW., and Muthukrishnan, S. (2003) Greenhouse and field testing of transgenic wheat plants stably expressing genes for thaumatin-like protein, chitinase and glucanase against Fusarium graminearum. J. Experim. Botany, 54 (384)1101-1111.
Velazhahan, R., Jayaraj, J., Liang, GH., and Muthukrishnan, S. (2003) Partial purification and N-terminal amino acid sequencing of a β-1,3-glucanase from sorghum leaves. Biologia Plantarum, 46:29-33.
Waniska, RD., Venkatesha, RV., Chandrashekar, A., Krishnaveni, S., Bejosano, FP., Jeoung, J., Jayaraj, J., Muthukrishnan, S., and Liang, GH. (2003) Antifungal proteins and other mechanisms in the control of sorghum stalk rot and grain mold. In: Sorghum and millet pathology III. ed. R. T. Venkatesha, Iowa State University Press. pp.287-298.
Anand, A., Trick, HN., Gill, BS., and Muthukrishnan, S. (2003) Stable transgene expression and random gene silencing in wheat. Plant Biotechnology Journal, 1:241-251.
Arakane Y., Zhu, Q., Matsumiya, M., Muthukrishnan. S., and Kramer, KJ. (2003) Properties of catalytic, linker and chitin-binding domains of insect chitinase. Insect Biochem. Molec. Biol., 33:631-648.
Velazhahan, R., and Muthukrishnan, S. (2003) Transgenic tobacco plants constitutively overexpressing a rice thaumatin-like protein (PR-5) show enhanced resistance to Alternaria alternata. Biologia Plantarum, 47:347-354.
Anand, A., Schmelz, EA., and Muthukrishnan, S. (2003) Development of a lesion-mimic phenotype in a transgenic wheat line over-expressing genes for pathogenesis-related (PR) proteins is dependent on salicylic acid concentration. Molec. Plant Microbe Interactions, 16:916-925.
Sridevi, G., Sabapathi, N., Meena, P., Nandakumar, R., Samiyappan, R., Muthukrishnan, S., and Veluthambi, K. (2003) Transgenic Indica Rice Variety Pusa Basmati 1 Constitutively Expressing a Rice Chitinase Gene Exhibits Enhanced Resistance to Rhizoctonia solani. J. Plant Biochemistry & Biotechnology, 12:93-101.
Zhu, Q., Deng, Y., Vanka, P., Brown, SJ., Muthukrishnan, S., and Kramer, KJ. (2004) Computational identification of novel chitinase-like proteins in the Drosophila melanogaster genome. Bioinformatics, 20:161-169.
Arakane, Y., Hogenkamp, DG., Zhu, Y-C., Kramer, KJ., Specht, CA., Beeman, RW., Kanost, MR., and Muthukrishnan, S. (2004) Characterization of two chitin synthase genes of the red flour beetle, Tribolium castaneum, and alternate exon usage in one of the genes during development. Insect Biochemistry and Molecular Biology, 34:291-304.
Ornatowski,W., Jayaraj, J., Schapaugh, WP., Muthukrishnan, S., Todd, TC., and Trick, HN. (2004) Introduction and constitutive expression of a tobacco hornworm (Manduca sexta) chitinase gene in soybean. In Vitro Cell. Dev. Biol. Plant, 40:260-265.
Jayaraj, J., Muthukrishnan, S., Liang, GH., and Velazhahan, R. (2004) Jasmonic acid and salicylic acid induce accumulation of b-1,3-glucanase and thaumatin-like proteins in wheat and enhance resistance against Stagonospora nodorum. Biologia Plantarum, 48:425- 430.
Jayaraj, J., Yi, H., Liang, GH., Muthukrishnan, S., and Velazhahan, R. (2004) Foliar application of Bacillus subtilis AUBS1 reduces sheath blight and triggers defense mechanisms in rice. J. Plant Diseases and Protection, 111:115-125
Jayaraj, J., Velazhahan, R., Fu, D., Liang, G., and Muthukrishnan, S. (2004) Bacterially produced rice thaumatin-like proteins shows in vitro antifungal activity. J. Plant Disease and protection, 111:334-344.
Anand, A., Lei, Z., Sumner, LW., Mysore, KS., Arakane Y., Bockus, WW., and Muthukrishnan, S. (2004). The apoplastic extracts from a transgenic wheat line exhibiting lesion-mimic phenotype have multiple pathogenesis-related proteins that are antifungal. Molec. Plant Microbe Interact, 17:1306-1317.
Jayaraj, J., Anand, A., and Muthukrishnan, S. (2004) Pathogenesis-related proteins and their role in resistance to fungal pathogens. In: Fungal disease resistance in plants- Biochemistry, Molecular biology and genetic Engineering (ed. Zamir K. Punja) Haworth Press, pp. 139-177.
Muthukrishnan, S., Weeks, T., Tuinstra, M., and Liang, GH. (2004) Sorghum transformation for resistance to fungal pathogens and drought. In: Genetically Modified Crops - Their Development, Uses, and Risks. G. H. Liang, D. E. Skinner (eds) Haworth Press, pp.203-223.
Skinner, DZ., Muthukrishnan, S., and Liang, GH. (2004) Transformation, a powerful tool for crop improvement. In: Genetically Modified Crops - Their Development, Uses, and Risks. G. H. Liang, D. E. Skinner (eds). Haworth Press. New York, pp.1-16.
Arakane, Y., Zhu, Q., Muthukrishnan, S., Beeman, RW., and Kramer, KJ. (2004) Molecular biology and functions of insect chitin synthase and chitinase genes. In: Proceedings of international symposium on “New Frontiers of Arthropod and Peptide Science, eds. M. Miyazawa and J. Ishibashi Tsukuba City, Japan, 37-42.
Jayayraj, J., Muthukrishnan, S., and Liang, GH. (2004) Transfer of a plant chitinase gene into a nitrogen-fixing Azospirillum and study of its expression. Can. J. Microbiol., 50: 509-513.
Kramer, KJ., and Muthukrishnan, S. (2005) Chitin metabolism in insects. In: Comprehensive Molecular Insect Science (eds. L. I. Gilbert, K. Iatrou, and S. S. Gill) Elsevier. Vol. 4:111-144.
Fu, D., Tisserat, NA., Xiao, Y., Settle, D., Muthukrishnan, S., and Liang, GH. (2005) Overexpression of rice TLPD34 enhances dollar-spot resistance in transgenic bentgrass. Plant Science, 168:671-680.
Gao, Z., Jayaraj, J., Muthukrishnan, S., Claflin, L., and Liang, GH. (2005) Efficient genetic transformation of sorghum using a visual screening marker. Genome, 48:321-333.
Zimoch, L., Hogenkamp, D., Kramer, KJ., Muthukrishnan, S., and Merzendorfer, H. (2005) Regulation of chitin synthesis in the larval midgut of Manduca sexta. Insect Biochem. Molec. Biol., 35:515-527.
Hogenkamp, DG., Arakane, Y., Zimoch, L., Merzendorfer, H., Kramer, KJ., Beeman, RW., Kanost, MR., Specht, CA., and Muthukrishnan, S. (2005) Chitin synthase genes in Manduca sexta: Characterization of a gut-specific transcript and differential tissue expression of alternately spliced mRNAs during development. Insect Biochem. Molec. Biol., 35:529-540.
Fu, D., Xiao, Y., Muthukrishnan, S., and Liang, GH. (2005) In vivo performance of a dual genetic marker, manA-gfp in transgenic bentgrass. Genome, 48:722-730.
Arakane, Y., Muthukrishnan, S., Beeman, RW., Kanost, MR., and Kramer, KJ. (2005) Laccase 2 is the phenoloxidase gene required for beetle cuticle tanning. Proc. Natl. Acad. Sci. USA., 102:11337-11342.
Arakane, Y., Muthukrishnan, S., Kramer, KJ., Specht, CA., Tomoyasu, Y., Lorenzen, MD., Kanost, MK., and Beeman, RW. (2005) The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrix. Insect Molec. Biol., 14:453-463.
Nagarajkumar, M., Jayaraj, J., Muthukrishnan, S., Bhaskaran, R., and Velazhahan, R. (2005) Detoxification of oxalic acid by Pseudomonas fluorescens strain pfMDU2: implications for the biological control of rice sheath blight caused by Rhizoctonia solani. Microbiol Res., 160:291-298.
Li, Z., Meyer, S., Essig, J., Liu, Y., Schapaugh, MA., Muthukrishnan, S., Hainline, BE., and Trick, HN. (2005) High level expression of maize-g-zein gene protein in transgenic soybean (Glycine max). Molec. Breed, 16:11- 20.
Bolognesi, R., Arakane, Y., Muthukrishnan, S., Kramer, KJ., Terra, WR., and Ferreira, C. (2005) Sequences of cDNAs and expression of genes encoding chitin synthase and chitinase in the midgut of Spodoptera frugiperda. Insect Biochem. Molec. Biol., 35:1249-1259.
Gao, Z., Xie, X., Ling, Y., Muthukrishnan, S., and Liang, GH. (2005) Agrobacterium tumefaciens-mediated sorghum transformation using mannose selection system. Plant Biotechnol, J. 3:591-599.
Fu, D., St. Amand, PC., Xiao, Y., Muthukrishnan, S., and Liang, GH. (2006) Characterization of T-DNA integration in creeping bentgrass. Plant Science, 170:225-237.
Matsumiya, M., Arakane, Y., Haga, A., Muthukrishnan, S., and Kramer, KJ. (2006) Substrate specificity of chitinases from two species of fish, greenling, Hexagrammos otakii, and common mackerel, Scomber japonicus, and the insect, tobacco hornworm, Manduca sexta. Bioscience, Biotechnology, and Biochemistry, 70:971-979.
Velazhahan, R., Jayaraj, J., Salaheddin, K., Sandoss Kumar, R., and Muthukrishnan, S. (2006) Xanthomonas oryzae pv. oryzae infection triggers accumulation of phenolics, defense-related enzymes and thaumatin-like proteins in rice leaves. Archives of Plant Pathology and Plant Protection, 39:329-339.
Fu, D., Huang, B., Xiao, Y., Muthukrshnan, S., and Liang, GH. (2007) Overexpression of barlely hva1 gene in creeping bentgrass for improving drought tolerance. Plant Cell Reports, 26(4):467-77
Fu, D., Huang, B., Xiao, Y., Muthukrishnan, S., and Liang, GH. (2007) Overexpression of Barley Gene in Creeping Bentgrass for Improving Drought Tolerance. Plant Cell Reports, 39:329-339.
Moreira, MF., dos Santos, AS., Marotta, HR., Mansur, JF., Ramos, IB., Machado, EA., Souza, GHMF., Eberlin, MN., Kaiser, CR., Kramer, KJ., Muthukrishnan, S., and Vasconcellos, AMH. (2007) A chitin-like component in Aedes aegypti eggshells, eggs and ovaries. Insect Biochem. Molec. Biol., 37:1249-1262.
Zhu, Q., Arakane, Y., Banerjee, D., Beeman, RW., Kramer, KJ., and Muthukrishnan, SM. (2008) Domain organization and phylogenetic analysis of the chitinase-like family of proteins in three species of insects. Insect Biochem. Molec. Biol., 38:452-466.
Zhu, Q., Arakane, Y., Beeman, RW., Kramer, KJ., and Muthukrishnan, SM. (2008) Characterization of recombinant chitinase-like proteins of Drosophila melanogaster and Tribolium castaneum. Insect Biochem. Molec. Biol., 38:467-477.
Hogenkamp, DJ., Arakane, Y., Kramer, KJ., Muthukrishnan, S., and Beeman, RW. (2008) Characterization and expression of the b-N-acetylglucosaminidase gene family of Tribolium castaneum. Insect Biochem. Molec. Biol., 38:478-489.
Dixit, R., Arakane, Y., Specht, CA., Richard, C., Kramer, KJ., Beeman, RW., and Muthukrishnan, S. (2008) Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects. Insect Biochem Mol Biol., 38:440-51.
Shrestha, CL., Ona, I., Muthukrishnan, S., and Mew, TW. (2008) Chitinase levels in rice cultivars correlate with resistance to the sheath blight pathogen Rhizoctonia solani. Eur. J. Plant Pathol., 120:69-77.
Tribolium Genome Sequencing Consortium (2008) Richards S, Gibbs RA, Weinstock GM, Brown SJ, Denell R, Beeman RW, Gibbs R, Beeman RW, Brown SJ, Bucher G, Friedrich M, Grimmelikhuijzen CJ, Klingler M, Lorenzen M, Richards S, Roth S, Schröder R, Tautz D, Zdobnov EM, Muzny D, Gibbs RA, Weinstock GM, Attaway T, Bell S, Buhay CJ, Chandrabose MN, Chavez D, Clerk-Blankenburg KP, Cree A, Dao M, Davis C, Chacko J, Dinh H, Dugan-Rocha S, Fowler G, Garner TT, Garnes J, Gnirke A, Hawes A, Hernandez J, Hines S, Holder M, Hume J, Jhangiani SN, Joshi V, Khan ZM, Jackson L, Kovar C, Kowis A, Lee S, Lewis LR, Margolis J, Morgan M, Nazareth LV, Nguyen N, Okwuonu G, Parker D, Richards S, Ruiz SJ, Santibanez J, Savard J, Scherer SE, Schneider B, Sodergren E, Tautz D, Vattahil S, Villasana D, White CS, Wright R, Park Y, Beeman RW, Lord J, Oppert B, Lorenzen M, Brown S, Wang L, Savard J, Tautz D, Richards S, Weinstock G, Gibbs RA, Liu Y, Worley K, Weinstock G, Elsik CG, Reese JT, Elhaik E, Landan G, Graur D, Arensburger P, Atkinson P, Beeman RW, Beidler J, Brown SJ, Demuth JP, Drury DW, Du YZ, Fujiwara H, Lorenzen M, Maselli V, Osanai M, Park Y, Robertson HM, Tu Z, Wang JJ, Wang S, Richards S, Song H, Zhang L, Sodergren E, Werner D, Stanke M, Morgenstern B, Solovyev V, Kosarev P, Brown G, Chen HC, Ermolaeva O, Hlavina W, Kapustin Y, Kiryutin B, Kitts P, Maglott D, Pruitt K, Sapojnikov V, Souvorov A, Mackey AJ, Waterhouse RM, Wyder S, Zdobnov EM, Zdobnov EM, Wyder S, Kriventseva EV, Kadowaki T, Bork P, Aranda M, Bao R, Beermann A, Berns N, Bolognesi R, Bonneton F, Bopp D, Brown SJ, Bucher G, Butts T, Chaumot A, Denell RE, Ferrier DE, Friedrich M, Gordon CM, Jindra M, Klingler M, Lan Q, Lattorff HM, Laudet V, von Levetsow C, Liu Z, Lutz R, Lynch JA, da Fonseca RN, Posnien N, Reuter R, Roth S, Savard J, Schinko JB, Schmitt C, Schoppmeier M, Schröder R, Shippy TD, Simonnet F, Marques-Souza H, Tautz D, Tomoyasu Y, Trauner J, Van der Zee M, Vervoort M, Wittkopp N, Wimmer EA, Yang X, Jones AK, Sattelle DB, Ebert PR, Nelson D, Scott JG, Beeman RW, Muthukrishnan S, Kramer KJ, Arakane Y, Beeman RW, Zhu Q, Hogenkamp D, Dixit R, Oppert B, Jiang H, Zou Z, Marshall J, Elpidina E, Vinokurov K, Oppert C, Zou Z, Evans J, Lu Z, Zhao P, Sumathipala N, Altincicek B, Vilcinskas A, Williams M, Hultmark D, Hetru C, Jiang H, Grimmelikhuijzen CJ, Hauser F, Cazzamali G, Williamson M, Park Y, Li B, Tanaka Y, Predel R, Neupert S, Schachtner J, Verleyen P, Raible F, Bork P, Friedrich M, Walden KK, Robertson HM, Angeli S, Forêt S, Bucher G, Schuetz S, Maleszka R, Wimmer EA, Beeman RW, Lorenzen M, Tomoyasu Y, Miller SC, Grossmann D, Bucher G. (2008) The genome of the model beetle and pest Tribolium castaneum. Nature, 452(7190): 949-55.
Zhu, Q., Arakane, Y., Beeman, RW., Kramer, KJ., and Muthukrishnan, S. (2008) Functional specialization among insect chitinase family genes revealed by RNA interference. PNAS., 105:6650-6655.
Arakane, Y., Specht, CA., Kramer, KJ., Beeman, RW., and Muthukrishnan, S. (2008) Chitin synthases are required for survival, fecundity, embryonic hatching in the red flour beetle, Tribolium castaneum. Insect Biochem. Mol. Biol., 38:959-962.
Arakane, Y., Li, Bin., Muthukrishnan, S., Beeman, RW., Kramer, KJ., and Park, Y. (2008) Functional analysis of four neuropeptides, EH, ETH, CCAP and bursicon, in adult ecdysis behavior of the red flour beetle, Tribolium castaneum. Mech Dev., 125:984-995.
Arakane, Y., Begum, K., Dixit, R., Park, Y., Specht, CA., Kramer, KJ., and Beeman, RW. (2009) Analysis of functions of the chitin deacetylase gene family in Tribolium castaneum. Insect Biochem Molec Biol., 38:959-962.
Khajuria, C., Zhu, Y-C., Chen, M-S., Buschman, LL., Higgins, RA., Yao, J., Crespo, AL-B., Siegfried, BD., Muthukrishnan, S., and Zhu, KY. (2009) Expressed sequence tags from larval gut of the European corn borer (Ostrinia nubilalis): Exploring candidate genes potentially involved in Bacillus thuringiensis toxicity and resistance. BMC Genomics, 10:286.
Arakane, Y., Lomakin, J., Beeman, RW., Muthukrishnan, S., Gehrke, SH., Kanost, MR., and Kramer, KJ. (2009) Molecular and functional analysis of amino acid decarboxylase involved in cuticle tanning in Tribolium castaneum. J. Biol. Chem., 284:16584-16594.
2010s
Arakane, Y., and Muthukrishnan, S. (2010) Insect chitinases and chitinase-like proteins. Cellular Molecular Life Sciences, 67:201-216.
Jasrapuria, S., Arakane, Y., Osman, G., Kramer, KJ., Beeman, RW., and Muthukrishnan, S. (2010) Genes encoding proteins with peritrophin A-type chitin binding domains in Tribolium castaneum are grouped into three distinct families based on phylogeny, expression and function. Insect Biochem Mol. Biol., 40:214-227.
Arakane, Y., Dittmer, N., Kramer, KJ., Muthukrishnan, S., Beeman, RW., and Kanost, M. (2010) Identification, mRNA expression and functional analyses of several yellow family genes in Tribolium castaneum. Insect Biochem Mol. Biol., 40:259-266.
Broehan, G., Arakane, Y., Beeman, RW., Kramer, KJ., Muthukrishnan, S., and Merzendorfer, H. (2010) Chymotrypsin-like peptidases from Tribolium castaneum: a role in molting revealed by RNA interference. Insect Biochem. Mol. Bio., 40:274-283.
Mansur, JF., Figueira-Mansur, J., Santos, AS., Santos-Junior, H., Ramos, IB., Neves de Medeiros, M., Machado, EA., Kaiser, CR., Muthukrishnan, S., Masuda, H., Vasconcellos, AMH., Melo, ACA., and Moreira, MF. (2010) The effect of lufenuron, a chitin synthesis inhibitor, on oogenesis of Rhodnius prolixus. Pesticide Biochemistry and Physiology, 98, 59–67.
Khajuria, C., Buschman, LL., Chen, M-S., Muthukrishnan, S., and Zhu, KY. (2010) A gut-specific chitinase gene essential for regulation of chitin content of peritrophic matrix and growth of Ostrinia nubilalis larvae. Insect Biochem. Mol. Biol., 40:621-629.
Arakane, Y., Baguinon, M., Jasrapuria, J., Chaudhari, S., Doyungan, A., Kramer, KJ., Muthukrishnan, S., and Beeman, RW. (2011) Both UDP N-acetylglucosamine pyrophosphorylases of Tribolium castaneum are critical for molting, survival and fecundity. Insect Biochem. Mol. Biol., 41:42-50.
Zhang, J., Zhang, X., Arakane, Y., Muthukrishnan, S., Kramer, KJ., Ma, E., and Zhu, KY. (2011) Comparative genomic analysis of chitinase and chitinase-like genes in the African malaria mosquito (Anopheles gambiae). PLoS One, 6(5):e19899. Epub 2011 May 18.
Zhang, J., Zhang, X., Arakane, Y., Muthukrishnan, S., Kramer, KJ., Ma, E., and Zhu, KY. (2011) Identification and characterization of a novel chitinase-like gene cluster (AgCht5) possibly derived from tandem duplications in the African malaria mosquito, Anopheles gambiae. Insect Biochem Mol Biol., 41:521-528.
Chaudhari, SS., Arakane, Y., Specht, CA., Moussian, B., Boyle, DL., Park, Y., Kramer, KJ., Beeman, RW., and Muthukrishnan, S. (2011) The Knickkopf protein protects and organizes chitin in the newly synthesized insect exoskeleton. Proc Natl Acad Sci USA., 108:17028-17033.
Muthukrishnan, S., Merzendorfer, H., Arakane, Y., and Kramer, KJ. (2012) Chitin metabolism in insects. In: Insect Biochemistry and Molecular Biology, (Ed. By. Gilbert, L.I.) Elsevier Inc., San Diego, ISBN:-978-0-12-384747-8. pp.193-235.
Merzendorfer, H., Kim, HS., Chaudhari, SS., Kumari, M., Specht, CA., Butcher, S., Brown, SJ., Manak, JR., Beeman, RW., Kramer, KJ., and Muthukrishnan, S. (2012) Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species, Tribolium castaneum. Insect Biochem. Mol. Biol., 42:264-276
Arakane, Y., Lomakin, J., Gehrke, SH., Hiromasa, Y., Tomich, JM., Muthukrishnan, S., Beeman, RW., Kramer, KJ., and Kanost, MR. (2012) Formation of rigid, non-flight forewings (elytra) of a beetle requires two major cuticular proteins. PLoS Genetics, 8(4): e1002682. doi:10.1371/journal.pgen.1002682
Janarthanan, S., Sakthivelkumar, S., Veeramani, V., Radhika, D., and Muthukrishanan, S. (2012) A new variant of antimetabolic protein, arcelin from an Indian bean, Lablab purpureus (Linn.) and its effect on the stored product pest, Callosobruchus maculates. Food Chemistry, 135:2839-2844
Jasrapuria, S., Specht, CA., Kramer, KJ., Beeman, RW., and Muthukrishnan, S. (2012) Gene Families of Cuticular Proteins Analogous to Peritrophins (CPAPs) in Tribolium castaneum have diverse functions. PLoS ONE, 7(11): e49844. doi:10.1371/journal.pone.0049844
Merzendorfer, H., Kim, HS., Chaudhari, SS., Kumari, M., Specht, CA., Butcher, S., Brown, SJ., Manak, JR., Beeman, RW., Kramer, KJ., and Muthukrishnan, S. (2012) Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species, Tribolium castaneum. Insect Biochem. Mol. Biol., 42:264-276
Chaudhari, SS., Arakane, Y., Specht, CA., Moussian, B., Kramer, KK., Muthukrishnan, S., and Beeman, RW. (2013) Retroactive maintains cuticle integrity by promoting the trafficking of Knickkopf into the procuticle of Tribolium castaneum." PLOS Genetics, PGENETICS-D-12-02532R1 10.1371/journal.pgen.1003268
Odman-Naresh, J., Duevel, M., Muthukrishnan, S., and Merzendorfer, H. (2014) A Lepidopteran-Specific Gene Family Encoding Valine-Rich Midgut Proteins. PLoS ONE, 8(11): e82015. doi:10.1371/journal.pone.0082015
Agrawal, S., Kelkenberg, M., Begum, K., Lea, S., Williams, CE., Kramer, KJ., Park, Y., Muthukrishnann, S., and Merzendorfer, M. (2014) Two essential peritrophic matrix proteins mediate matrix barrier functions in the insect midgut. Insect Biochemistry and Molecular Biology, 49:24-34 doi.org/10.1016/j.ibmb.2014.03.00
Mun, S., Noh, MY., Osanai-Futahashi, M., Muthukrishnan, S., Kramer, KJ., and Arakane, Y. (2014) A Major Facilitator Superfamily protein encoded by TcMucK gene is not required for cuticle pigmentation, growth and development in Tribolium castaneum. Insect Biochem Mol Biol., 49:43-8 DOI: 10.1016/j.ibmb.2014.03.007
Noh, MY., Kramer, KJ., Muthukrishnan, S., Kanost, MR., Beeman, RW., and Arakane, Y. (2014) Two major cuticular proteins are required for assembly of horizontal laminae and vertical pore canals in rigid cuticle of Tribolium castaneum. Insect Biochem. Mol. Biol. 53: 22-29.
Chaudhari, SS., Moussian, B., Specht, CA., Arakane, Y., Kramer, KJ., Beeman, RW., and Muthukrishnan, S. (2014) Functional specialization among members of knickkopf family of proteins in insect cuticle organization. PloS Genet 10(8):e1004537. doi:10.1371/journal.pgen. 1004537
Tetreau, G., Dittmer, N.T., Cao, X., Agrawal, S., Chen, Y., Muthukrishnan, S., Haobo, J., Blissard, G.W., Kanost, M.R., and Wang, P. (2014) "Analysis of Chitin-binding proteins from Manduca sexta provides new insights into evolution of peritrophin A-type chitin-binding domains in insects." Insect Biochem Mol Biol. Dec 15 pii:S0965-1748(14)00195-7. doi: 10.1016/j.bmb.2014.12.002.
Noh, MY., Kramer, KJ., Muthukrishnan, S., Beeman, Rw., Kanost, MR., and Arakane, Y. (2015) "Loss of function of the yellow-e gene causes dehydration-induced mortality of adult Tribolium castaneum." Dev Biol. Jan. 19. pii:S0012-1606(15)00017-2. doi:10.1016/j.ydbio.2015.01.009
Tetreau, G., Cao, X., Chen, YR., Muthukrishnan, S., Haobo, J., Blissard, GW., Kanost, MR., and Wang, P. (2015) "Overview of chitin metabolism enzymes in Manduca sexta: Identification, domain organization, phylogenetic analysis and gene expression." Insect Biochem Mol Biol. Jan. 20. pii:S0965-1748(15)00013-2. doi:10.1016/j.ibmb
Chaudhari, SS., Noh, MY., Moussian, B., Specht, CA., Kramer, KJ., Beeman, RW., Arakane, Y., and Muthukrishnan, E. (2015) "Knickkopf and retroactive proteins are required for formation of laminar serosal procuticle during embryonic development of Tribolium castaneum" Insect Biochem. and Mol. Biol. doi: 10.1016/j.ibmb.2015.02.013
Kelkenberg, M., Odman-Naresh, J., Muthukrishnan, S., and Merzendorfer, H. (2015) "Chitin is a necessary component to maintain the barrier function of the peritrophic matrix in the insect midgut" Insect Biochem. and Mol. Biol. 56 (2015) 21e28
Noh, MY., Muthukrishnan, S., Kramer, KJ., and Arakane, Y. (2015) “Tribolium castaneum RR-1 cuticular protein TcCPR4 is required for formation of pore canals in rigid cuticle.” PLoS Genet 2015 Feb 9;11(2):e1004963.
Doi: 10.1371/journal.pgen.1004963.eCollection 2015 Feb.
Zhu, K.Y., Merzendorfer, H., Zhang, W., Zhang, J., and Muthukrishnan, S. (2016) Biosynthesis, turnover, and functions of chitin in insects. Annual Review of Entomology, 61: 177-196.
Noh MY, Muthukrishnan S, Kramer KJ, Arakane Y (2018) A chitinase with two catalytic domains is required for organization of the cuticular extracellular matrix of a beetle. PLoS Genet 14(3): e1007307.
https://doi.org/10.1371/journal.pgen.1007307
2020s
Mun, S., Noh, M. Y., Kramer, K. J., Muthukrishnan, S., Arakane, T. Gene functions in adult cuticle pigmentation of the yellow mealworm, Tenebrio molitor. 2020. Insect Biochem. Molec. Biol. 117, 103291 doi: 10.1016/j.ibmb.2019.103291
Mi Young Noha, Sung Hyun Kimb, Maureen J. Gorman, Karl J. Kramer, Subbaratnam Muthukrishnan, Yasuyuki Arakane. Yellow-g and Yellow-g2 proteins are required for egg desiccation resistanceand temporal pigmentation in the Asian tiger mosquito, Aedes albopictus. Insect Biochemistry and Molecular Biology 122 (2020) 103386.
Qu, M., Guo, X., Tian, S., Yang, Q., Kim, M., Mun, S., Noh, M. Y., Kramer, K. J., Muthukrishnan, S., Arakane, Y. 2022. AA15 lytic polysaccharide monooxygenase is required for efficient chitinous cuticle turnover during insect molting. Communications Biology 5, 518.
Mun, S., Noh, M. Y., Geisbrecht, E. R., Kramer, K. J., Muthukrishnan, S., Arakane, Y. 2022. Chitin deacetylases are necessary for insect femur muscle attachment and mobility. Proceedings of the National Academy of Sciences USA 119, e2120853119.
Lee, Y., Muthukrishnan, S., Kramer, K. J., Sakamoto, H., Tabunoki, H., Arakane, Y., Noh, M. Y. Functional importance of groups I and II chitinases in cuticle chitin turnover during molting in a wood-boring beetle, Monochamus alternatus. 2023. Pest. Biochem. Physiol.194, 105496
Books edited
Datta, S. K., and Muthukrishnan (1999) Pathogenesis-Related Proteins in Plants. CRC Press, Boca Raton, FL. ISBN: 0-8493-0697 288pp.
Journals edited
Insect Biochemistry and Molecular Biology, Special issue on insect cuticle, Vol #40, April 2010. Co-editor with Dr. Judy Willis.
Patents issued
Recombinant chitinase and use thereof as a biocide. U. S. Patent No. 5,866,788. With K. J. Kramer, H. Choi, K. Choi, L. Corpuz, and B. Gopalakrishnan.