Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
Manhattan, KS 66506
785-532-6121
785-532-7278 fax
biochem@k-state.edu



Biotechnology Core Facility
206 Burt Hall
785-532-5956
785-532-6297 fax



Biomolecular NMR Facility
37 Chalmers Hall
785-532-2345

Subbaratnam Muthukrishnan, Ph.D., University Distinguished Professor
Lead Advisor

Complete publications list

1960s | 1970s | 1980s | 1990s | 2000s | 2010s | Books edited | Journals edited | Patents issued

1960s

Padmanabhan, G., Muthukrishnan, S., and Sarma, P. S. (1967) The role of iron in heme synthesis in Neurospora crassa. Biochem. Biophys. Acta 141: 187-190.

Muthukrishnan, S., Padmanabhan, G., and Sarma, P. S. (1968) Role of iron in the regulation of heme biosynthesis in N. crassa. Biochem. Biophys. Res. Commun. 31: 333-339.

Padmanabhan, G., Muthukrishnan, S., Subramanian, K. N., and Sarma, P. S. (1968) The in vivo donor for heme synthesis in Neurospora crassa. Indian J. Biochem. 5: 153-156.

Muthukrishnan, S., Padmanabhan, G., and Sarma, P. S. (1969) Regulation of heme biosynthesis in Neurospora crassa. J. Biol. Chem. 244: 4241-4246.


1970s

Rao, M.R.S., Padmanabhan, G., Muthukrishnan, S., and Sarma, P. S. (1970) Feedback inhibition of delta-aminolevulinate dehydratase by coproporphyrinogen III. Indian J. Biochem. 7: 132-133.

Muthukrishnan, S. Replication of single-stranded viral RNA. (1971) J. Sci. Ind. Res. 30: 28-38.

Muthukrishnan, S., Malathi, K., and Padmanabhan, G. (1972) delta-Aminolevulinate dehydratase-regulatory enzyme of the heme biosynthetic pathway in Neurospora crassa. Biochem. J. 129:31-37.

Rothman-Denes, L. B., Muthukrishnan, S., Haselkorn, R., and Studier, W. (1972) A T7 gene shuts off host and early viral transcription. Virus Research, Academic Press. 227-239.

Muthukrishnan, S. and Shatkin, A.J. Reovirus (1975) Genome RNA Structure: Resistance to S1 Nuclease. Virology 64: 96-105.

Furuichi, Y., Morgan, M., Muthukrishnan, S., and Shatkin, A. J. (1975) Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: 7mG5 ppp5 GMP Cp. Proc. Natl. Acad. Sci. USA 72: 362-366.

Furuichi, Y., Muthukrishnan, S., and Shatkin, A. J. (1975) 5'-terminal 7mG5 ppp5' Gmp in vivo:  Identification in reovirus genome RNA. Proc. Natl. Acad. Sci. USA 72: 742-745.

Muthukrishnan, S., Both, G. W., Furuichi, Y., and Shatkin, A. J. (1975) 5'-terminal 7-Methylguanosine in eukaryotic mRNA is required for translation. Nature 255: 33-37.

Both, G. W., Furuichi, Y., Muthukrishnan, S., and Shatkin, A. J. (1975) Ribosome binding to mRNA in protein synthesis requires 5'-terminal 7-methylguanosine. Cell 6: 185-195.

Shatkin, A. J., Banerjee, A. K., Both, G. W., Furuichi, Y., and Muthukrishnan, 1975  5'-terminal 7-methylguanosine in eukaryotic mRNAs in its requirement for translation. EMBO Workshop on "In Vitro Transcription and Translation," Thivernal, France, Vol. 255:33-37.

Muthukrishnan, S., Filipowicz, W., Sierra, J. M., Both, G. W., Shatkin, A. J., and Ochoa, S. (1975)  mRNA methylation and protein synthesis in extracts from embryos of brine shrimp, Artemia Saline. J. Biol. Chem. 250, 9336-9341.

Shatkin, A. J., Banerjee, A. K., Both, G. W., Furuichi, Y., and Muthukrishnan, S. (1976) Dependence of translation of 5'-terminal methylation of mRNA. Fed. Proc. 35, 2214-2217.

Both, G. W., Furuichi, Y., Muthukrishnan, S., and Shatkin, A. J. (1976) Effect of 5'-terminal structure and base composition on polyribonucleotide binding to ribosomes. J. Mol. Biol. 104: 637-658.

Furuichi, Y., Muthukrishnan, S., Tomasz, J., and Shatkin, A. J. (1976) Mechanism of formation of reovirus mRNA 5'-terminal blocked and methylated sequence, m7GpppGmpC. J. Biol. Chem. 251: 5043-5053.

Shatkin, A. J., Both, G. W., Furuichi, Y., Kozak, M., and Muthukrishnan, S. (1976) 5'-Terminal 7-methylguanosine in viral mRNAs and its role in translation. In "Animal Virology" (ICN-UCLA Symposia on Molecular and Cellular Biology). Eds:  D. Baltimore, A. S. Huang, C. F. Fox. pp. 659-676.

Filipowicz, W., Furuichi, Y., Sierra, J. M., Muthukrishnan, S., Shatkin, A. J., and Ochoa, S. (1976) A protein binding the methylated 5'-terminal cap, m7GpppN, of eukaryotic messenger RNA. Proc. Natl. Acad. Sci. USA 73: 1559-1563.

Furuichi, Y., Muthukrishnan, S., Tomasz, J., and Shatkin, A. J. (1976) Caps in Eukaryotic mRNAs:  Mechanisms of formation of reovirus mRNA 5'-terminal  m7GpppGmpC. Prog. Nucl. Acid Res. and Mol. Biol. 19: 3-20.

Muthukrishnan, S., Furuichi, Y., Both, G. W., and Shatkin, A. J. (1976) Effect of 5'-terminal structures on the binding of ribopolymers to eukaryotic ribosomes. Prog. Nucl. Acid Res. and Mol. Biol. 19: 473-476.

Muthukrishnan, S., Morgan, J., Banerjee, A. K., and Shatkin, A. J. (1976) Influence of 5'-terminal m7G and 2-0-methylated residues on mRNA binding to ribosomes. Biochemistry 15: 5761-5768.

Muthukrishnan, S., Moss, B., Cooper, J. A. and Maxwell, E. S. (1978) Influence of 5'-terminal cap structure on the initiation of translation of vaccinia virus mRNA. J. Biol. Chem. 253: 1710-1715.

Adams, B. L., Morgan, M., Muthukrishnan, S., Hecht, S. M. and Shatkin, A. J. (1978) The effect of Cap analogs on reovirus mRNA binding to wheat germ ribosomes. J. Biol. Chem. 253: 2589-2596.

Keith, J. M., Muthukrishnan, S. and Moss, B. (1978) Effect of methylation of the N6 position of the penultimate adenosine of capped mRNA on ribosome binding. J. Biol. Chem. 253: 5039-5041.

Wodnar-Filipowicz, A., Szczesna, E., Zan-Kowalczewska, M., Muthukrishnan, S., Szybiak, U., Legocki, A. B. and Filipowicz, W. (1978) 5'-Terminal 7-methylguanosine and mRNA function. Eur. J. Biochem. 92: 69-80.

Chandra, G. R., Muthukrishnan, S. and Maxwell, E. S. (1979) Hormonal regulation of genome activity in higher plants. In "Plant Growth Substances" (ACS Symposium Series III) (Mandava, N. B., Ed.), pp. 245-261.

Muthukrishnan, S., Maxwell, E. S. and Chandra, G. R. (1979) Hormone-induced increase in the levels of functional mRNA and alpha-amylase mRNA in barley aleurones. Proc. Natl. Acad. Sci. USA 76: 6181-6185.

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1980s

Muthukrishnan, S. mRNA methylation in plants. (1982) In "Biochemistry of S-adenosylmethionine and Related Compounds" (Usdin, E., Borchardt, R., and Creweling, R., Eds.), MacMillan Press, pp. 329-338.

Muthukrishnan, S. and Chandra, G. R. (1983) Expressions of alpha-amylase genes in barley aleurone cells.   Beltsville Symposia on Agricultural Research 7:151-159.

Muthukrishnan, S., Chandra, G. R. and Maxwell, E. S. (1983) Hormonal control of alpha-amylase gene expression in barley--studies using a cloned cDNA probe. J. Biol. Chem. 258: 2370-2375.

Muthukrishnan, S., Chandra, G. R., and Albaugh, G. P. (1983) Modulation by abscisic acid and S-2-aminoethyl-L-cysteine of alpha-amylase mRNA in barley aleurone cells. Plant Molec. Biol. 2: 249-258.

Huang, J.-K, Swegle, M., Dandekar, A. and Muthukrishnan, S. (1984) Expression and regulation of α-amylase gene family in barley aleurones. J. Molec. Appl. Genet. 2:579-588.

Muthukrishnan, S., Gill, B. S. and Chandra, G. R. (1984) Structural genes for α-amylases are located on barley chromosomes 1 and 6.   J. Biol. Chem. 259: 13637-640.

Chandra, G. R., Albaugh, G. P. and Muthukrishnan, S. (1985) Methodology for gene expression.   CRC Handbook of Naturally Occurring Pesticides. Vol. II (ed. Mandava, N. B.) CRC Press, Boca Raton, pp. 493-523.

Kumar, S., Chandra, G. R., Albaugh, G. P. and Muthukrishnan, S. (1985) Regulation of the expression of alpha-amylase genes by sodium butyrate. Plant Molec. Biol. 5:269-279.

Kalinski, A., Chandra, G. R., and Muthukrishnan, S. (1986). Study of barley endonucleases and alpha-amylase genes. J. Biol. Chem. 261:11393-11397.

Knox, C.A.P., Sonthayanon, B., Chandra, G. R., and Muthukrishnan, S. (1987) Structure and organization of two divergent alpha-amylase genes from barley. Plant Molecular Biology, 9:3-17.

Wang, C.S.W., Shastri, K., Wen, L., Huang, J-K., Sonthayanon, B., Muthukrishnan, S., and Reeck, G.R. (1987) Heterogeneity in cDNA clones encoding rice glutelin. FEBS Letters 222:135-138.

Muthukrishnan, S. and Chandra, G. R. (1988). Regulation of the expression of hydrolase genes in cereals. Advances in Cereal Science and Technology (ed. by Y. Pomeranz) Vol. IX: 129-159.

Rahmatullah, R.J., Huang, J-K., Clark, K.L., Reeck, G.R., Chandra, G.R., and Muthukrishnan, S. (1989)  Nucleotide and predicted amino acid sequences of two different genes for high pI alpha-amylases from barley. Plant Molec Biol. 12:119-121.

Lee, S.H., Muthukrishnan, S., Sorensen, E.L., and Liang G.H. (1989) Restriction endonuclease analysis of mitochondrial DNA from sorghum with fertile and male-sterile cytoplasms. Theoretical and Applied Genetics 77:379-382.

Kam-Morgan, l., Gill, B.S., and Muthukrishnan, S. (1989)  DNA restriction fragment length polymorphisms: a strategy for rapid genetic mapping of the polyploid genome of wheat. Genome 32:724-732.

Swegle, M.S.,  Huang, J.K., Lee, G., and Muthukrishnan, S. (1989) Identification of an endochitinase cDNA clone from barley aleurone cells. Plant Molecular Biol. 12:403-412.

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1990s

Feng, G.H., Wen, L., Huang, J.-K., Shorrosh, B.S., Muthukrishnan, S., and Reeck, G.R. (1990). Nucleotide sequence of a cloned rice genomic DNA fragment that encodes a 10 kDA prolamin polypeptide. Nuc. Acids Res. 18:683.

Chen, Z., Liang, G.H., Muthukrishnan, S., and Kofoid, K.D. (1990) Chloroplast DNA polymorphism in fertile and male-sterile cytoplasms of sorghum (Sorghum bicolor (L.) Moench). Theor Appl. Genet. 80:727-731.

Lee, G., Sonthayanon, B., Huang, J-K., Chandra, G.R., and  Muthukrishnan, S. (1990). Regulation of barley alpha-amylase genes by abscisic acid. Proceedings of the International Congress of Plant Physiology. S. K. Sinha, P.V. Sanw, S.C. Bhargava, P.K. Agrawal eds. Vedams Books International, New Delhi. Vol 2: 795-799.

Chandra G.R, and Muthukrishnan S. (1990). Gibberellins modulate plant genome activity. Proceedings of the International Congress of Plant Physiology. S. K. Sinha, P.V. Sanw, S.C. Bhargava, P.K. Agrawal eds.   Vedams Books International, New Delhi. Vol 2: 715-720.

Gopalakrishnan, B., Sonthayanon, B., Rahmatullah, R., and Muthukrishnan, S. (1991)  Barley aleurone layer cell protoplasts as a transient expression system. Plant Molec. Biol. 16:463-467.

Corpuz, L.M., Choi, H., Muthukrishnan, S., and Kramer K.J. (1991) Sequence and expression of two cDNA clones encoding methionine-rich storage proteins of Manduca sexta. Insect Biochemistry 21: 265-276.

Huang, J-K.,  Wen, L., Swegle, M., Tran, H-C.,  Thin, T. H.,  Naylor, H. M., Muthukrishnan, S.,  Reeck, G. R. (1991) Nucleotide sequence of a rice genomic clone that encodes a class I endochitinase Plant Molec. Biol. 16:479-480.

Wen, L., Huang, J-K., Zen, K-C., Johnson, B.H., Muthukrishnan, S., MacKay, V., Manney T.R., Manney M., and Reeck, G.R. (1992). Nucleotide sequence of a cDNA clone that encodes the maize inhibitor of trypsin and activated Hageman factor. Plant Molec Biol 18:813-814.

Sharrosh, B.S., Wen, L., Zen, K.C., Huang J-K., Pan J.S., Hermodson, M.A., Tanaka, K., Muthukrishnan, S., and Reeck, G.R. (1992) A novel cereal storage protein: molecular genetics of the 19 kDa globulin of rice. Plant Molecular Biology  18:151-154.

Anuratha, C. S., Huang, J-K., Pingali, A., and Muthukrishnan, S. (1992). Isolation and characterization of a chitinase and its cDNA clone from rice. J. Plant Biochem. & Biotech. Vol. 3:91-95.

Chen, M-S., Johnson, B., Wen, L., Muthukrishnan, S., Kramer, K.J., Morgan, T.D., and Reeck, G.R. (1992) Rice cystatin: Bacterial expression, purification, cysteine proteinase inhibitory activity and insect growth suppressing activity of a truncated form of the protein. Protein Expression and Purification. 3:41-49

Koga D., Funakoshi T., Mizuki K., Ide A., Kramer K. J., Zen K. C., Choi H., and Muthukrishnan S. (1992) Immunoblot analysis of chitinolytic enzymes in integument and molting fluid of the silkworm, Bombyx mori and the tobacco hornworm, Manduca sexta. Insect Biochem Mol Biol 22:305-311.

Swegle, M., Kramer, K.J., and Muthukrishnan, S. (1992) Properties of barley seed chitinases and release of embryo-associated isoforms during early stages of imbibition. Plant Physiology. 99:1009-1014

Chen Z., Muthukrishnan S., Liang G. H., Schertz K. F., and Hart G. E. (1993) CMS-associated chloroplast DNA deletion located in RNA polymerase gene rpoC2 in sorghum. Molecular and General Genet. 236:251-259.

Darnetty, Leslie, J.F., Muthukrishnan, S., Swegle, M., Vigers, A., Selitrennikoff, C.P. (1993) Variability in antifungal proteins in the grains of maize, sorghum and wheat. Physiologia Plantarum  88: 339-349.

Kramer, K.J., Corpuz, L., Choi, H.K., Muthukrishnan, S. (1993) Sequence of a cDNA and expression of the gene encoding epidermal and gut chitinases of Manduca sexta. Insect Biochem Molec Biol 23: 691-701.

Shu, G., Muthukrishnan, S., Liang, G.H., and Paulsen, G. (1993). Restriction fragment patterns of chloroplast and mitochondrial DNA of Daspyrum villosum (L.) candargy and wheats. Theoretical and Applied Genetics. 87: 44-48.

Ignatius, M. J. S., Chopra, R. K., and Muthukrishnan, S. (1994) Effects of fungal infection and wounding on the expression of chitinases and beta-1,3-glucanases in near-isogenic lines of barley. Physiologia Plantarum 90: 584-592.

Ignatius, M. J. S., Huang J-K., Chopra, R. K., and Muthukrishnan, S. (1994) Isolation and characterization of a barley chitinase genomic clone- Expression in powdery-mildew infected barley. J Plant Bioch & Biotech. 3:91-95.

Gopalakrishnan, B., Muthukrishnan, S., and Kramer, K. J. (1995)  Baculovirus-mediated expression of a Manduca sexta chitinase gene: Properties of the recombinant protein. Insect Bioch Mol Biol 25: 255-265.

Lin, W., Anuratha, C. S., Datta, K., Potrykus, I., Muthukrishnan, S., and Datta, S. K. (1995)  Genetic engineering of rice for resistance to sheath blight. Bio/Technology 13:686-691.

Anuratha, C. S., Zen, K. C., Cole, K. C., Mew, T., Muthukrishnan, S. (1996) Induction of chitinases and beta-glucanases in Rhizoctonia solani-infected rice plants: Isolation of an infection-related chitinase cDNA clone. Physiologia Plantarum 97:39-46.

Zen, K. C., Choi, H. K., Nandigama, K., Muthukrishnan, S. and  Kramer, K. J. (1996) Cloning, expression and hormonal regulation of an insect beta-N-acetylglucosaminidase gene. Insect Biochem. Molec. Biol. 26:435-444.

Lin, W., Gopalakrishnan, B., and Muthukrishnan, S. (1996) Transcription efficiency and hormone-responsiveness of alpha-amylase gene promoters in an improved transient expression system from barley aleurone protoplasts. Protoplasma 192:93-108.

Wang, X., Ding, X., Gopalakrishnan, B., Morgan, T.D., Johnson, L.B., White, F.F., and Kramer, K.J.(1996) Characterization of a 46 kDa insect chitinase from transgenic tobacco. Insect Biochem. Molec. Biol. 26:1055-1064.

Choi, H. K., Choi, K. H., Kramer, K. J., and Muthukrishnan, S. (1997) Isolation and characterization of a genomic clone for the gene of an insect molting enzyme, chitinase. Insect Biochem. Molec. Biol. 27:37-47.

Kramer, K. J., Muthukrishnan, S., Johnson, L. B., and White, F.(1997)  Chitinases for insect control. In: Transgenic Plants for Control of Insect Pests. (N. Carozzi and M. Koziel, eds.), Taylor and Francis Publ., Washington, D. C. pp.185-193.

Vidhyasekaran, P., Ponmalar, T. R., Samiyappan, R., Velazhzhan, R., Vimala, R., Ramanathan, A., Paranidharan, V., and Muthukrishnan, S. (1997) Host-specific toxin production by Rhizoctonia solani, the rice sheath blight pathogen. Phytopathology, 87:1258-1263.

Sriram, S., Raghuchander T., Vidhyasekaran, P., Muthukrishnan, S., and Samiyappan, R. (1997) Genetic relatedness with special reference to viruelence among the isolates of Rhizoctonia solani causing sheath blight in rice. J. Plant Diseases & Protection 104:260-271.

Kramer, K. J. and Muthukrishnan, S. (1997) Insect Chitinases:Molecular biology and potential use as biopesticides. Insect Biochem  Molec. Biol. 27:887-900.

Liang, G., Skinner, D. Z., and Muthukrishnan, S. (1997) Crop improvement using microprojectile bombardment and Agrobacterium-mediated transformation. Trends in Agronomy 1: 57-73.

Ding X., Gopalakrishnan, B., Johnson, L. White F. F. Wang, X., Morgan, T. D., Kramer, K. J., and Muthukrishnan, S. (1998)  Insect resistance of transgenic tobacco expressing an insect chitinase gene. Transgenic Research 7:77-84.

Velazhahan, R., Chen-Cole, K., Anuratha, C. S. and Muthukrishnan, S. (1998) Induction of thaumatin-like proteins (TLPs) in Rhizoctonia solani-infected rice and characterization of two new cDNA clones. Physiologia Plantarum, 102:21-28.

Hazeg-Azam, M., Kim, S., Masoud, S., Andersson, L., White, F., Johnson, L., Muthukrishnan, S. and Reeck. (1998) The corn inhibitor of activated Hagemen factor: Purification and properties of two recombinant forms of the protein. Protein Expression and Purification. 13:143-149.

Chen, W. P., Chen, P. D., Liu, D. J., Muthukrishnan, S., and Gill, B. S. (1998) Constitutive expression a rice thaumatin-like protein gene in T0, T1, and T2 transgenic wheat plants. In: Proceedings of the 9th International Wheat Genetics Symposium, ed. A. E. Slinkarol,  Vol. 3, 169-171.

Zhu, H., Krishnaveni, Liang, G. H., and Muthukrishnan, S. (1998)  Biolistic transformation of sorghum using a rice chitinase gene. J. Genet. Breed. 52:243-252.

Chen, W. P., Gu, X., Liang, G. H., Muthukrishnan, S., Chen, P. D., Liu, D. J., and Gill, B. S. (1998) Introduction and constitutive expression of a rice chitinase gene in bread wheat using biolistic bombardment and the bar gene as a selectable marker. Theor. Appl. Genet. 97:1296-1306.

Chareonpornwattana, S., Thara, K. V., Wang, L., Datta, S. K., Panbangred, W., and Muthukrishnan, S. (1999) Inheritance, expression, and silencing of a chitinase transgene in rice. Theor. Appl. Genet. 98: 371-378.

Datta, K.,Velazhahan, R.,  Oliva, N., Mew, T., Muthukrishnan, S., and Datta, S. K. (1999) Over-expression of thaumatin-like protein (PR-5) gene in transgenic rice plants enhances environmentally friendly resistance to Rhizoctonia solani causing sheath blight disease. Theor. Appl. Genet. 98:1138-1145.

Velazhahan, R., Datta, S. K., and Muthukrishnan, S. (1999) The PR-5 family; Thaumatin-like Proteins. In:  Pathogenesis-Related Proteins in Plants. Ed. S. K. Datta and S. Muthukrishnan, CRC Press, Boca Raton, FL . ISBN:0-8493-0697, 107-129

Datta, K., Muthukrishnan, S., and Datta, S. K. (1999) Expression and function of PR-protein genes in transgenic plants. In: Pathogenesis-Related Proteins in Plants.   Ed. S. K. Datta and S. Muthukrishnan,  CRC Press, Boca Raton, FL . ISBN:0-8493-0697, 261-277.

Krishnaveni, S., Liang, G. H., S. Muthukrishnan, and A. Manickam (1999) Purification and partial characterization of chitinases from sorghum seeds. Plant Science 144:1-7.

Krishnaveni, S., Muthukrishnan, S., Liang, G. H., Wilde, G., and A. Manickam (1999) Induction of chitinases and beta-1,3-glucanases in resistant and sensitive cultivars of sorghum in response to insect attack, fungal infection and wounding. Plant Science 144:9-16.

Chen, W.P., Chen, P. D., Liu, D. J., Kynast, R. J., Friebe, B., Velazhahan, R., Muthukrishnan, S., and Gill, B. S. (1999) Development of wheat scab symptoms is delayed in transgenic wheat plants that constitutively express a rice thaumatin-like protein gene. Theor. Appl. Genet. 99:755-760.

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2000s

Huang, X., Zhang, H., Zen, K. C., Muthukrishnan, S., and Kramer, K. J. (2000) Homology modeling of the insect chitinase catalytic domain-oligosaccharide complex and the role of a putative active site tryptophan in catalysis. Insect Biochem. Molec. Biol. 30:107-117.

Yu, T.T., Skinner, D. Z. Liang, G. H., Trick. H. N. Muthukrishnan, S. (2000) Agrobacterium-mediated transformation of creeping bentgrass using GFP as reporter gene. Hereditas 133:229-233.

Li, W.L., Faris,  J.D., Muthukrishnan, S., Liu, D.J., Chen, P.D., Gill, B.S. (2001) Isolation and characterization of novel cDNA clones of acidic chitinases and beta-1,3-glucanases from wheat spikes infected by Fusarium graminearum   Theor. Appl. Genet.102:353-362.

Datta, K., Tu, J.M., Oliva, N., Ona, I., Velazhahan, R., Mew, T. W., Muthukrishnan, S., and Datta, S.K. (2001) Enhanced resistance to sheath blight by constitutive expression of infection-related rice chitinase in transgenic elite Indica rice cultivars. Plant Sci. 160:405-414.

Muthukrishnan, S., Liang, G. H., Trick, H. N., and Gill, B. S. (2001) Pathogenesis-related proteins and their genes in cereals. Plant Cell, Tissue and Organ Culture. 64:93-114.

Jackson, S. A., Zhang, P., Chen, W., Phillips, R. L., Friebe, B., S. Muthukrishnan, S., and Gill, B. S. (2001) High resolution structural analysis of biolistic transgene integration into nuclear genome of wheat. Theor. Appl. Genet. 103:56-62.

Velazhahan, R., Radhajeyalakshmi, R., Thangavelu, R., and Muthukrishnan, S. (2001) An antifungal protein purified from pearl millet seeds shows sequence homology to lipid transfer proteins. Biologia Plantarum. 43(3):417-421.

Zhu, X.,  Zhang, H., Fukamizo, T., Muthukrishnan, S. and Kramer, K. J. (2001) Properties of Manduca sexta Chitinase and its C-Terminal Deletions. Insect Biochem. Molec. Biol. 31:1221-1230.

Waniska, R. D., Venkatesha, R. V., Chandrashekar, A., Krishnaveni, S., Bejosano, F. P., Jeoung, J., Jayaraj, J., Muthukrishnan, S., and Liang, G. H. (2001). Antifungal proteins and other mechanisms in the control of sorghum stalk rot and grain mold. J. Agric. Food. Chem. 49:4732-4742.

Muthukrishnan, S., Kramer, K. J., Zhang, H., Lu, Y., and Matsumiya, M. and Anand, A. (2001). Use of chitinases as Biopesticides. In: Chitin and Chitosan - Chitin and Chitosan in Life Science (ed. T. Uragami, K. Kurita & T. Fukamizo). Kodansha Scientific Ltd. ISBN 4-906464-13-0. pp. 415-418

Velazhahan, R., Zen, K. C., and Muthukrishnan, S. (2001). Expression of a rice thaumatin-like protein (PR-5) gene in a baculovirus expression system. Acta Phytopathologica et Entomologica Hungarica, 36: 311-316.

Krishnaveni, S., Jeoung, J-M., S. Muthukrishnan, and G. H., Liang (2001) Transgenic sorghum plants constitutively expressing a rice chitinase gene show improved resistance to stalk rot. J. Genet. & Breeding 55:151-158.

Thangavelu, R., Palaniswami, A., Ramakrishnan, G., Doraiswami, S., Muthukrishnan, S., and Velazhahan, R. (2001). Involvement of fusaric acid detoxification by Pseudomonas fluorescens strain Pf10 in the biological control of Fusarium wilt of banana caused by Fusarium oxysporum f. sp. cubense. J. Plant Disease and Protection 108: 433-445.

Zhu, Y-C., Muthukrishnan, S. and Kramer, K. J. (2002) cDNA sequences and mRNA levels of two hexamerin storage proteins pinSP1 and PinSP2 from the Indianmeal moth Plodia interpunctella. Insect Biochem. Molec. Biol. 32:525-536.

Sakthivel, N., Amudha, R., and Muthukrishnan, S. (2002) Production of cytotoxic metabolites by Sarocladium oryzae. Mycological Research 106:5:609-614.

Zhu, Y-C., Specht, C. A., Dittmer, N., Muthukrishnan, S., Kanost, M. R., Kramer, K. J. (2002) Sequence of a cDNA and Expression of the Gene Encoding a Putative Epidermal Chitin Synthase of Manduca sexta. Insect Biochem. Mol. Biol. 32:1497-1506.

Lu, Y., Zen, K-C., Muthukrishnan, S., Kramer, K. J.(2002) Site-directed mutagenesis and functional analysis of active site acidic amino acid residues D142, D144, and E146 in Manduca sexta (tobacco hornworm) chitinase. Insect Biochemistry and Molecular Biology 32:1369-1382.

Zhang, H., Huang, X., Fukamizo, T., Muthukrishnan, S., Kramer, K. J. (2002) Site-directed mutagenesis and functional analysis of an active site tryptophan of insect chitinase. Insect Biochemistry and Molecular Biology 32:1477-1488.

Velazhahan, R., Jayaraj, J., Jeoung, J-M., Liang, G. H., and Muthukrishnan, S. (2002) Purification and characterization of an antifungal thaumatin-like protein from sorghum leaves. J. Plant Diseases & Protection 109: 452-461.

Jeoung, J. M., Krishnaveni, S., Muthukrishnan, S., Trick, H.N., Liang, G.H. (2002) Optimization of sorghum transformation parameters using genes for green fluorescent protein and β-glucuronidase as visual markers. Hereditas 137:20-28

Anand, A., Zhou, T., Trick, H. N., Gill, B. S., Bockus, W. W., and Muthukrishnan, S. (2003) Greenhouse and field testing of transgenic wheat plants stably expressing genes for thaumatin-like protein, chitinase and glucanase against Fusarium graminearum. J. Experim. Botany. 54 (384) 1101-1111.

Velazhahan, R., Jayaraj, J., Liang, G. H., and Muthukrishnan, S. (2003) Partial purification and N-terminal amino acid sequencing of a β-1,3-glucanase from sorghum leaves. Biologia Plantarum 46: 29-33.

Waniska, R. D., Venkatesha, R. V., Chandrashekar, A., Krishnaveni, S., Bejosano, F. P., Jeoung, J., Jayaraj, J., Muthukrishnan, S., and Liang, G. H. (2003). Antifungal proteins and other mechanisms in the control of sorghum stalk rot and grain mold. In: Sorghum and millet pathology III. ed. R. T. Venkatesha, Iowa State University Press. pp.287-298.

Anand, A., Trick, H. N., Gill, B. S., and Muthukrishnan, S. (2003) Stable transgene expression and random gene silencing in wheat. Plant Biotechnology Journal 1:241-251.

Arakane Y., Zhu, Q., Matsumiya, M., Muthukrishnan. S., and Kramer, K. J. (2003) Properties of catalytic, linker and chitin-binding domains of insect chitinase. Insect Biochem. Molec. Biol. 33: 631-648.

Velazhahan, R., and Muthukrishnan, S. (2003) Transgenic tobacco plants constitutively overexpressing a rice thaumatin-like protein (PR-5) show enhanced resistance to Alternaria alternata. Biologia Plantarum 47:347- 354.

Anand, A., Schmelz, E. A. and Muthukrishnan, S. (2003) Development of a lesion-mimic phenotype in a transgenic wheat line over-expressing genes for pathogenesis-related (PR) proteins is dependent on salicylic acid concentration. Molec. Plant Microbe Interactions. 16: 916-925.

Sridevi, G., Sabapathi, N., Nandakumar, R., Samiyappan, R., Muthukrishnan, S., and Veluthambi, K. (2003). Transgenic Indica Rice Variety Pusa Basmati 1 Constitutively Expressing a Rice Chitinase Gene Exhibits Enhanced Resistance to Rhizoctonia solani. J. Plant Biochemistry & Biotechnology (12):93-101.

Zhu, Q., Deng, Y., Vanka, P., Brown, S. J., Muthukrishnan, S.,  Kramer, K. J. (2004). Computational identification of novel chitinase-like proteins in the Drosophila melanogaster genome. Bioinformatics 20:161- 169.

Arakane, Y., Hogenkamp, D. G., Zhu, Y-C., Kramer, K. J., Specht, C. A., Beeman, R. W., Kanost, M. R., and Muthukrishnan, S. (2004) Characterization of two chitin synthase genes of the red flour beetle, Tribolium castaneum, and alternate exon usage in one of the genes during development. Insect Biochemistry and Molecular Biology 34:291-304.

Ornatowski,W., Jayaraj, J., Schapaugh, W.P., Muthukrishnan, S., Todd, T.C., and Trick, H.N. (2004). Introduction and constitutive expression of a tobacco hornworm (Manduca sexta) chitinase gene in soybean. In Vitro Cell. Dev. Biol. Plant. 40: 260-265.

Jayaraj, J., Muthukrishnan, S., Liang, G. H. and Velazhahan R. (2004). Jasmonic acid and salicylic acid induce accumulation of b-1,3-glucanase and thaumatin-like proteins in wheat and enhance resistance against Stagonospora nodorum. Biologia Plantarum,  48 : 425- 430.

Jayaraj, J., Yi, H., Liang, G. H.,  Muthukrishnan, S.,  and Velazhahan, R. (2004). Foliar application of Bacillus subtilis AUBS1 reduces sheath blight and triggers defense mechanisms in rice. J. Plant Diseases and Protection 111:115-125

Jayaraj, J., Velazhahan, R., Fu, D., Liang, G., and Muthukrishnan, S. (2004). Bacterially produced rice thaumatin-like proteins shows in vitro antifungal activity. J. Plant Disease and protection. 111:334-344.

Anand, A., Lei, Z., Sumner, L. W., Mysore, K. S., Arakane Y., Bockus, W. W. and Muthukrishnan, S. (2004). The apoplastic extracts from a transgenic wheat line exhibiting lesion-mimic phenotype have multiple pathogenesis-related proteins that are antifungal. Molec. Plant Microbe Interact. 17:1306-1317.

Jayaraj, J., Anand, A., and Muthukrishnan, S. (2004) Pathogenesis-related proteins and their role in resistance to fungal pathogens. In: Fungal disease resistance in plants- Biochemistry, Molecular biology and genetic Engineering (ed. Zamir K. Punja) Haworth Press, pp. 139-177.

Muthukrishnan, S., Weeks, T., Tuinstra, M., and Liang G. H. (2004). Sorghum transformation for resistance to fungal pathogens and drought. In: Genetically Modified Crops - Their Development, Uses, and Risks. G. H. Liang, D. E. Skinner (eds) Haworth Press, pp.203-223.

Skinner, D. Z., Muthukrishnan, S., and Liang, G. H. (2004). Transformation, a powerful tool for crop improvement. In: Genetically Modified Crops - Their Development, Uses, and Risks. G. H. Liang, D. E. Skinner (eds). Haworth Press. New York, pp.1-16.

Arakane, Y., Zhu, Q., Muthukrishnan, S., Beeman, R. W. and Kramer, K. J. (2004). Molecular biology and functions of insect chitin synthase and chitinase genes. In: Proceedings of international symposium on “New Frontiers of Arthropod and Peptide Science, eds. M. Miyazawa and J. Ishibashi Tsukuba City, Japan, 37-42.

Jayayraj, J., Muthukrishnan, S., and Liang, G. H. (2004). Transfer of a plant chitinase gene into a nitrogen-fixing Azospirillum and study of its expression. Can. J. Microbiol. 50: 509-513.

Kramer, K. J., and Muthukrishnan, S. (2005). Chitin metabolism in insects. In: Comprehensive Molecular Insect Science (eds. L. I. Gilbert, K. Iatrou, and S. S. Gill) Elsevier. Vol. 4, 111-144.

Fu, D., Tisserat, N. A., Xiao, Y., Settle, D., Muthukrishnan, S., and Liang, G. H. (2005). Overexpression of rice TLPD34 enhances dollar-spot resistance in transgenic bentgrass. Plant Science 168: 671-680.

Gao, Z., Jayaraj, J., Muthukrishnan, S., Claflin, L. and Liang, G.H. (2005). Efficient genetic transformation of sorghum using a visual screening marker. Genome 48: 321-333.

Zimoch L., Hogenkamp D., Kramer K. J., Muthukrishnan S. and Merzendorfer H. (2005). Regulation of chitin synthesis in the larval midgut of Manduca sexta. Insect Biochem. Molec. Biol. 35: 515-527.

Hogenkamp, D.G., Arakane, Y., Zimoch, L., Merzendorfer, H., Kramer,K. J., Beeman, R. W., Kanost, M. R., Specht, C. A. and Muthukrishnan. S. (2005). Chitin synthase genes in Manduca sexta: Characterization of a gut-specific transcript and differential tissue expression of alternately spliced mRNAs during development. Insect Biochem. Molec. Biol. 35: 529-540.

Fu, D., Xiao, Y., Muthukrishnan, S., and Liang, G. H. (2005). In vivo performance of a dual genetic marker, manA-gfp in transgenic bentgrass. Genome 48:722-730.

Arakane, Y., Muthukrishnan, S., Beeman, R. W., Kanost, M. R., and Kramer, K. J. (2005). Laccase 2 is the phenoloxidase gene required for beetle cuticle tanning. Proc. Natl. Acad. Sci. USA, 102: 11337-11342.

Arakane, Y., Muthukrishnan, S., Kramer, K. J., Specht, C. A., Tomoyasu, Y., Lorenzen, M. D., Kanost, M. K., and Beeman R. W. (2005). The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrix. Insect Molec. Biol. 14: 453-463.

Nagarajkumar M, Jayaraj J, Muthukrishnan S, Bhaskaran R, Velazhahan R. (2005). Detoxification of oxalic acid by Pseudomonas fluorescens strain pfMDU2: implications for the biological control of rice sheath blight caused by Rhizoctonia solani. Microbiol Res. 160: 291-298.

Li, Z., Meyer, S., Essig, J., Liu, Y., Schapaugh, M. A., Muthukrishnan, S., Hainline, B. E., and Trick, H. N. (2005). High level expression of maize-g-zein gene protein in transgenic soybean (Glycine max). Molec. Breed. 16: 11- 20.

Bolognesi, R., Arakane, Y., Muthukrishnan, S., Kramer, K. J., Terra, W. R., and Ferreira, C. (2005). Sequences of cDNAs and expression of genes encoding chitin synthase and chitinase in the midgut of Spodoptera frugiperda. Insect Biochem. Molec. Biol. 35:1249-1259.

Gao, Z., Xie, X., Ling, Y., Muthukrishnan, S. and Liang, G. H. (2005). Agrobacterium tumefaciens-mediated sorghum transformation using mannose selection. Plant Biotechnol. J. 3: 591-599.

Fu, D., St. Amand, P.C., Xiao, Y., Muthukrishnan, S., and Liang. G. H. (2006) Characterization of T-DNA integration in creeping bentgrass. Plant Science, 170:225-237.

Matsumiya, M., Arakane, Y., Haga, A., Muthukrishnan, S. and Kramer, K.J. (2006). Substrate specificity of chitinases from two species of fish, greenling, Hexagrammos otakii, and common mackerel, Scomber japonicus, and the insect, tobacco hornworm, Manduca sexta. Bioscience, Biotechnology, and Biochemistry. 70: 971-979.

Velazhahan, R., Jayaraj, J., Salaheddin, K., Sandoss Kumar, R. & Muthukrishnan, S. (2006) Xanthomonas oryzae pv. oryzae infection triggers accumulation of phenolics, defense-related enzymes and thaumatin-like proteins in rice leaves. Archives of Plant Pathology and Plant Protection. 39: 329-339.

Fu, D., B. Huang, Y. Xiao, S. Muthukrishnan, and G.H. Liang. 2006. Overexpression of Barley Gene in Creeping Bentgrass for Improving Drought Tolerance. Plant Cell Reports. 39:329-339.

Moreira, M. F., dos Santos, A. S., Marotta, H.R., Mansur, J. F., Ramos, I. B., Machado, E. A., Souza, G. H. M. F., Eberlin, M. N., Kaiser, C. R., Kramer, K. J., Muthukrishnan, S., & Vasconcellos, A. M. H. (2007) A chitin-like component in Aedes aegypti eggshells, eggs and ovaries. Insect Biochem. Molec. Biol. 37: 1249-1262.

Zhu, Q., Arakane, Y., Banerjee, D., Beeman, R. W., Kramer, K. J., and Muthukrishnan, S. M. (2008) Domain organization and phylogenetic analysis of the chitinase-like family of proteins in three species of insects. Insect Biochem. Molec. Biol. 38: 452-466.

Zhu, Q., Arakane, Y., Beeman, R. W., Kramer, K. J., and Muthukrishnan, S. M. (2008) Characterization of recombinant chitinase-like proteins of Drosophila melanogaster and Tribolium castaneum. Insect Biochem. Molec. Biol. 38: 467-477.

Hogenkamp, D. J., Arakane, Y., Kramer, K. J., Muthukrishnan, S., and Beeman, R.W. (2008) Characterization and expression of the b-N-acetylglucosaminidase gene family of Tribolium castaneum. Insect Biochem. Molec. Biol. 38: 478-489.

Dixit R, Arakane Y, Specht CA, Richard C, Kramer KJ, Beeman RW, Muthukrishnan S. (2008) Domain organization and phylogenetic analysis of proteins from the chitin deacetylase gene family of Tribolium castaneum and three other species of insects. Insect Biochem Mol Biol. 38:440-51.

Shrestha, C. L., Ona, I., Muthukrishnan, S., and Mew, T. W. (2008) Chitinase levels in rice cultivars correlate with resistance to the sheath blight pathogen Rhizoctonia solani. Eur. J. Plant Pathol. 120: 69-77.

Tribolium Genome Sequencing Consortium (2008) Richards S, Gibbs RA, Weinstock GM, Brown SJ, Denell R, Beeman RW, Gibbs R, Beeman RW, Brown SJ, Bucher G, Friedrich M, Grimmelikhuijzen CJ, Klingler M, Lorenzen M, Richards S, Roth S, Schröder R, Tautz D, Zdobnov EM, Muzny D, Gibbs RA, Weinstock GM, Attaway T, Bell S, Buhay CJ, Chandrabose MN, Chavez D, Clerk-Blankenburg KP, Cree A, Dao M, Davis C, Chacko J, Dinh H, Dugan-Rocha S, Fowler G, Garner TT, Garnes J, Gnirke A, Hawes A, Hernandez J, Hines S, Holder M, Hume J, Jhangiani SN, Joshi V, Khan ZM, Jackson L, Kovar C, Kowis A, Lee S, Lewis LR, Margolis J, Morgan M, Nazareth LV, Nguyen N, Okwuonu G, Parker D, Richards S, Ruiz SJ, Santibanez J, Savard J, Scherer SE, Schneider B, Sodergren E, Tautz D, Vattahil S, Villasana D, White CS, Wright R, Park Y, Beeman RW, Lord J, Oppert B, Lorenzen M, Brown S, Wang L, Savard J, Tautz D, Richards S, Weinstock G, Gibbs RA, Liu Y, Worley K, Weinstock G, Elsik CG, Reese JT, Elhaik E, Landan G, Graur D, Arensburger P, Atkinson P, Beeman RW, Beidler J, Brown SJ, Demuth JP, Drury DW, Du YZ, Fujiwara H, Lorenzen M, Maselli V, Osanai M, Park Y, Robertson HM, Tu Z, Wang JJ, Wang S, Richards S, Song H, Zhang L, Sodergren E, Werner D, Stanke M, Morgenstern B, Solovyev V, Kosarev P, Brown G, Chen HC, Ermolaeva O, Hlavina W, Kapustin Y, Kiryutin B, Kitts P, Maglott D, Pruitt K, Sapojnikov V, Souvorov A, Mackey AJ, Waterhouse RM, Wyder S, Zdobnov EM, Zdobnov EM, Wyder S, Kriventseva EV, Kadowaki T, Bork P, Aranda M, Bao R, Beermann A, Berns N, Bolognesi R, Bonneton F, Bopp D, Brown SJ, Bucher G, Butts T, Chaumot A, Denell RE, Ferrier DE, Friedrich M, Gordon CM, Jindra M, Klingler M, Lan Q, Lattorff HM, Laudet V, von Levetsow C, Liu Z, Lutz R, Lynch JA, da Fonseca RN, Posnien N, Reuter R, Roth S, Savard J, Schinko JB, Schmitt C, Schoppmeier M, Schröder R, Shippy TD, Simonnet F, Marques-Souza H, Tautz D, Tomoyasu Y, Trauner J, Van der Zee M, Vervoort M, Wittkopp N, Wimmer EA, Yang X, Jones AK, Sattelle DB, Ebert PR, Nelson D, Scott JG, Beeman RW, Muthukrishnan S, Kramer KJ, Arakane Y, Beeman RW, Zhu Q, Hogenkamp D, Dixit R, Oppert B, Jiang H, Zou Z, Marshall J, Elpidina E, Vinokurov K, Oppert C, Zou Z, Evans J, Lu Z, Zhao P, Sumathipala N, Altincicek B, Vilcinskas A, Williams M, Hultmark D, Hetru C, Jiang H, Grimmelikhuijzen CJ, Hauser F, Cazzamali G, Williamson M, Park Y, Li B, Tanaka Y, Predel R, Neupert S, Schachtner J, Verleyen P, Raible F, Bork P, Friedrich M, Walden KK, Robertson HM, Angeli S, Forêt S, Bucher G, Schuetz S, Maleszka R, Wimmer EA, Beeman RW, Lorenzen M, Tomoyasu Y, Miller SC, Grossmann D, Bucher G. The genome of the model beetle and pest Tribolium castaneum. Nature, 452(7190): 949-55.

Zhu, Q., Arakane, Y., Beeman, R.W., Kramer, K.J., and Muthukrishnan, S. (2008) Functional specialization among insect chitinase family genes revealed by RNA interference. PNAS. 105:6650-6655.

Arakane, Y., Specht, C. A., Kramer, K. J., Beeman, R. W., Muthukrishnan, S., (2008). Chitin synthases are required for survival, fecundity, embryonic hatching in the red flour beetle, Tribolium castaneum. Insect Biochem. Mol. Biol. 38: 959-962.

Arakane, Y., Li, Bin. Muthukrishnan, S., Beeman, R. W., Kramer, K. J. and Park, Y. (2008) Functional analysis of four neuropeptides, EH, ETH, CCAP and bursicon, in adult ecdysis behavior of the red flour beetle, Tribolium castaneum. Mech Dev. 125: 984-995.

Arakane, Y., Begum, K., Dixit, R., Park, Y., Specht, C. A., Kramer, K. J., Beeman, R. W. (2009). Analysis of functions of the chitin deacetylase gene family in Tribolium castaneum. Insect Biochem Molec Biol. 38: 959-962.

Khajuria, C., Zhu, Y-C., Chen, M-S., Buschman, L. L., Higgins, R. A., Yao, J., Crespo, A. L-B., Siegfried, B. D., Muthukrishnan, S., and Zhu, K. Y. (2009) Expressed sequence tags from larval gut of the European corn borer (Ostrinia nubilalis): Exploring candidate genes potentially involved in Bacillus thuringiensis toxicity and resistance. BMC Genomics, 10: 286.

Arakane, Y., Lomakin, J., Beeman, R.W., Muthukrishnan, S., Gehrke, S.H., Kanost, M.R. and Kramer, K.J. (2009) Molecular and functional analysis of amino acid decarboxylase involved in cuticle tanning in Tribolium castaneum. J. Biol. Chem. 284, 16584-16594.

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2010s

Arakane, Y., Muthukrishnan, S. (2010) Insect chitinases and chitinase-like proteins. Cellular Molecular Life Sciences, 67, 201-216.

Jasrapuria, S., Arakane, Y., Osman, G., Kramer, K.J., Beeman, R. W., Muthukrishnan, S. Genes encoding proteins with peritrophin A-type chitin binding domains in Tribolium castaneum are grouped into three distinct families based on phylogeny, expression and function. Insect Biochem Mol. Biol. 40: 214-227.

Arakane, Y., Dittmer, N., Kramer, K. J., Muthukrishnan, S., Beeman, R. W., and Kanost, M. (2010). Identification, mRNA expression and functional analyses of some yellow family genes in Tribolium castaneum. Insect Biochem Mol. Biol. 40: 259-266.

Gunnar B., Arakane, Y., Beeman R. W., Kramer, K. J., Muthukrishnan, S., and Merzendorfer, H. (2010). Chymotrypsin-like peptidases from Tribolium castaneum: RNA interference reveals physiological functions in molting. Insect Biochem. Mol. Bio. 40: 274-283.

Mansur, J. F., Figueira-Mansur, J., Santos, A. S., Santos-Junior, H., Ramos, I. B., Neves de Medeiros, M., Machado, E. A., Kaiser, C. R., Muthukrishnan, S., Masuda, H., Vasconcellos, A. M. H., Melo, A. C.A., Moreira, M. F. (2010). The effect of lufenuron, a chitin synthesis inhibitor, on oogenesis of Rhodnius prolixus. Pesticide Biochemistry and Physiology 98, 59–67.

Khajuria, C., Buschman, L. L., Chen, M-S., Muthukrishnan, S., and Zhu, K. Y. (2010) A gut-specific chitinase gene essential for regulation of chitin content of peritrophic matrix and growth of Ostrinia nubilalis larvae. Insect Biochem. Mol. Biol., 40: 621-629.

Arakane, Y., Baguinon, M., Jasrapuria, J., Chaudhari, S., Doyungan, A., Kramer, K.J., Muthukrishnan, S., Beeman, R. W. (2011) Both UDP N-acetylglucosamine pyrophosphorylases of Tribolium castaneum are critical for molting, survival and fecundity. Insect Biochem. Mol. Biol. 41: 42-50.

Zhang J, Zhang X, Arakane Y, Muthukrishnan S, Kramer KJ, Ma E, Zhu KY. (2011) Comparative genomic analysis of chitinase and chitinase-like genes in the African malaria mosquito (Anopheles gambiae). PLoS One. 6(5):e19899. Epub 2011 May 18.

Zhang J, Zhang X, Arakane Y, Muthukrishnan S, Kramer KJ, Ma E, Zhu KY. (2011) Identification and characterization of a novel chitinase-like gene cluster (AgCht5) possibly derived from tandem duplications in the African malaria mosquito, Anopheles gambiae. Insect Biochem Mol Biol. 2011: 41:521-528.

Chaudhari, S. S., Arakane, Y., Specht, C. A., Moussian, B., Boyle, D. L., Park, Y., Kramer, K. J., Beeman, R. W., Muthukrishnan, S. (2011) The Knickkopf protein protects and organizes chitin in the newly synthesized insect exoskeleton. Proc Natl Acad Sci USA. 108:17028-17033.

Muthukrishnan, S., Merzendorfer, H., Arakane, Y., Kramer, K. J. (2012). Chitin metabolism in insects. In: Insect Biochemistry and Molecular Biology. Ed. By. Gilbert, L. I. Elsevier Inc., San Diego, ISBN:-978-0-12-384747-8. pp.193-235.

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Books edited

Datta, S. K., and Muthukrishnan (1999) Pathogenesis-Related Proteins in Plants. CRC Press, Boca Raton, FL. ISBN: 0-8493-0697 288pp.


Journals edited

Insect Biochemistry and Molecular Biology, Special issue on insect cuticle, Vol #40, April 2010. Co-editor with Dr. Judy Willis.


Patents issued

Recombinant chitinase and use thereof as a biocide. U. S. Patent No. 5,866,788. With K. J. Kramer, H. Choi, K. Choi, L. Corpuz, and B. Gopalakrishnan.

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