Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
Manhattan, KS 66506
785-532-6121
785-532-7278 fax
biochem@k-state.edu



Biotechnology Core Facility
206 Burt Hall
785-532-5956
785-532-6297 fax



Biomolecular NMR Facility
37 Chalmers Hall
785-532-2345

Maureen Gorman, Ph.D., Research Assistant Professor

Complete Publications List

2010s | 2000s | 1990s

2010s

Lang, M., Braun, C.L., Kanost, M.R., and Gorman, M.J. (2012) Multicopper oxidase-1 is a ferroxidase essential for iron homeostasis in Drosophila melanogaster. Proceedings of the National Academy of Sciences, USA doi: 10.1073/pnas.1208703109.

Lang, M., Kanost, M.R., and Gorman, M.J. (2012) Multicopper oxidase-3 is a laccase associated with the peritrophic matrix of Anopheles gambiae. PLoS One 7: e33985.

Keshar, P., Nguyen, T.D.T., Gorman, M.J. Barrigan, L.M., Peng, Z., Kanost, M.R., Syed, L.U., Li, J., Zhu, K.Y., and Hua, D.H. (2012) Redox Potentials, laccase oxidation, and antilarval activities of substituted phenols. Bioorganic & Medicinal Chemistry 20: 1679-1689.

Gorman, M.J., Sullivan, L.I., Nguyen, T.D.T., Dai, H., Dittmer, N.T., Syed, L.U., Li, J., Hua, D.H., and Kanost, M.R. (2012) Kinetic properties of alternatively spliced isoforms of laccase-2 from Tribolium castaneum and Anopheles gambiae.Insect Biochem. and Mol. Biol. 42,193-202.

Gorman, M.J., and Arakane, Y. (2010) Tyrosine hydroxylase is required for cuticle sclerotization and pigmentation in Tribolium castaneum. Insect Biochemistry and Molecular Biology 40: 267-273.


2000s

Dittmer, N.T., Gorman, M.J., and Kanost, M.R. (2009) Characterization of endogenous and recombinant forms of laccase-2, a multicopper oxidase from the tobacco hornworm, Manduca sexta. Insect Biochemistry and Molecular Biology 39: 596-606.

Gorman MJ, Dittmer NT, Marshall JL, and Kanost MR (2008) Characterization of the multicopper oxidase gene family in Anopheles gambiae. Insect Biochem. Molec. Biol. 38, 817-824.

Kanost, M.R., and Gorman, M.J. (2008) Phenoloxidases in insect immunity. In Insect Immunology (N. Beckage, ed), Academic Press/Elsevier, San Diego, pp. 69-96.

Gorman, M.J., An, C., and Kanost, M.R. (2007) Characterization of tyrosine hydroxylase from Manduca sexta. Insect Biochemistry and Molecular Biology 37: 1327-1337.

Gorman, M.J., Wang, Y., Jiang, H., and Kanost, M.R. (2007) Manduca sexta hemolymph proteinase 21 activates prophenoloxidase activating proteinase 3 in an insect innate immune response proteinase cascade. Journal of Biological Chemistry 282: 11742-11749.

Gorman, M.J., P. Kankanala, and Kanost, M.R. (2004) Bacterial challenge stimulates innate immune responses in extra-embryonic tissues of tobacco hornworm eggs. Insect Molecular Biology 13:19-24.

Dittmer, N.T., R.J. Suderman, H. Jiang, Y.C. Zhu, M.J. Gorman, K.J. Kramer, and Kanost, M.R. (2004) Characterization of cDNAs encoding putative laccase-like multicopper oxidases and developmental expression in the tobacco hornworm, Manduca sexta, and the malaria mosquito, Anopheles gambiae. Insect Biochemistry and Molecular Biology 34: 29-41.

Zhu, Y., Y. Wang, M.J. Gorman, H. Jiang, and Kanost, M.R. (2003) Manduca sexta serpin-3 regulates prophenoloxidase activation in response to infection by inhibiting prophenoloxidase-activating proteinases. Journal of Biological Chemistry 278: 46556-46564.

Gorman, M.J., and Paskewitz, S.M. (2001) Serine proteases as mediators of mosquito immune responses. Insect Biochemistry and Molecular Biology 31: 257-262.

Gorman, M.J., O.V. Andreeva, and S.M. Paskewitz (2000) Sp22D: a multidomain serine protease with a putative role in insect immunity. Gene 251: 9-17.

Gorman, M.J., and Paskewitz, S.M. (2000) Persistence of infection in mosquitoes injected with bacteria. Journal of Invertebrate Pathology 75: 296-297.

Gorman, M.J., O.V. Andreeva, and Paskewitz, S.M. (2000) Molecular characterization of five serine protease genes cloned from Anopheles gambiae hemolymph. Insect Biochemistry and Molecular Biology 30: 35-46.

Back to top


1990s

Paskewitz, S.M., S. Reese-Stardy, and Gorman, M.J. (1999) An easter-like serine protease from Anopheles gambiae exhibits changes in transcript abundance following immune challenge. Insect Molecular Biology 8: 329-337.

Paskewitz, S.M., and Gorman, M.J. (1999) Mosquito immunity and malaria parasites. American Entomologist 45: 80-94.

Gorman, M.J., A.M. Schwartz, and Paskewitz, S.M. (1998) The role of surface characteristics in eliciting humoral encapsulation of foreign bodies inPlasmodium-refractory and -susceptible strains of Anopheles gambiae. Journal of Insect Physiology 44: 947-954.

Han, Y.S., C.E. Salazar, S.R. Reese-Stardy, A.J. Cornel, M.J. Gorman, F.H. Collins, and Paskewitz, S.M. (1997) Cloning and characterization of a serine protease from the human malaria vector, Anopheles gambiae. Insect Molecular Biology 6: 385-395.

Gorman, M.J., D.W. Severson, A.J. Cornel, F.H. Collins, and Paskewitz, S.M. (1997) Mapping a quantitative trait locus involved in melanotic encapsulation of foreign bodies in the malaria vector,Anopheles gambiae. Genetics 146: 965-971.

Gorman, M.J., and Paskewitz, S.M. (1997) A genetic study of a melanization response inPlasmodium-refractory and -susceptible strains of Anopheles gambiae. American Journal of Tropical Medicine and Hygiene 56: 446-451.

Gorman, M.J., A.J. Cornel, F.H. Collins, and Paskewitz, S.M. (1996) A shared genetic mechanism for melanotic encapsulation of CM-Sephadex beads and a malaria parasite,Plasmodium cynomolgi B, in the mosquito, Anopheles gambiae. Experimental Parasitology 84: 380-386.

Gorman, M.J., and Kaufman, T.C. (1995) Genetic analysis of embryonic cis-acting elements of the Drosophila homeotic gene Sex combs reduced. Genetics 140: 557-572.

Flory, N., M. Gorman, P.M. Coutino, C. Ford, and Reilly, P.J. (1994) Thermosensitive mutants of Aspergillus awamori glucoamylase by random mutagenesis: inactivation kinetics and structural interpretation. Protein Engineering 7: 1005-1012.

Gorman, M., and Girton, J. (1992) Genetic analysis ofdeltex and its interaction with the Notch locus in Drosophila melanogaster. Genetics 131:99-112.

Back to top