Department of Biochemistry & Molecular Biophysics
141 Chalmers Hall
Manhattan, KS 66506
785-532-6121
785-532-7278 fax
biochem@k-state.edu



Biotechnology Core Facility
206 Burt Hall
785-532-5956
785-532-6297 fax



Biomolecular NMR Facility
37 Chalmers Hall
785-532-2345

Courses

Course schedules

Fall 2013 | Summer 2013 | Spring 2013

Course descriptions

Course number
Course name/description
Credits
Semesters offered
Prerequisites
BIOCH 100
Biochemistry Orientation

Discussion of biochemistry as a descipline in the life sciences.

1    
BIOCH 110
Biochemistry and Society

Biochemically oriented topics and news items related to environmental and medical aspects of daily living. Covers selected basic biochemical concepts with applications to humans: proteins as enzymes, energy from foods, biochemical communications and drug interactions, genes and heredity. Intended for nonscience majors.

3 I and II  
BIOCH 111
Biochemistry and Society Laboratory

Experiments to promote understanding of chemicals and reactions in living systems. Three hours lab a week. Intended for nonscience majors.

1 I and S BIOCH 110 or concurrent enrollment
BIOCH 265
Introductory Organic and Biochemistry

For students in human ecology, nursing, and other areas desiring an integrated organic and biochemistry course to provide an understanding of carbohydrates, proteins, lipids, and digestive metabolic systems. Three hours lecture and six hours lab a week.

5 I and II CHM 110
BIOCH 290
Biochemistry Seminar

Lectures and discussions on basic topics in biochemistry.

2 II BIOCH 100
BIOCH 399
Sophomore Honors Seminar in Biochemistry

Lecture, guided reading, and discussion of topics of general interest in biochemistry. Topics will vary depending on the interests and backgrounds of students enrolled.

3 II Freshman Honors Seminar
BIOCH 499
Senior Honors Thesis

Open only to seniors in the arts and sciences honors program. May be used by honors students to satisfy B.S. requirement for BIOCH 799.

2 I, II and S BIOCH 755 or concurrent enrollment
BIOCH 521
General Biochemistry

A basic study of the chemistry and metabolism of carbohydrates, lipids, proteins, and nucleic acids.

3 I, II and S CHM 350
BIOCH 522
General Biochemistry Laboratory

A one-semester laboratory course with experiments relating to carbohydrates, lipids, proteins, nucleic acids, and enzymes. Six hours lab a week.

2 I, II and S CHM 351 and BIOCH 521 or concurrent enrollment
BIOCH 590
Physical Studies of Biomacromolecules

An overview of concepts and techniques of physical science used in studying the structure and function of biomacromolecules such as proteins and DNA. Applications include classical equiilibrium thermodynamics and spectroscopic methods including mass spectrometry, circular dichroism (CD), and nuclear magnetic resonance (NMR).

3 II CHM 500, MATH 221, and PHYS 114
BIOCH 599
Research Training in Biochemistry

Provides laboratory experience for majors and nonmajors in research techniques contributing to ongoing biochemical research. May be repeated up to 8 hours.

1 to 3 I, II and S Background adequate for relevent techniques
BIOCH 700
Advanced Topics in Plant Biochemistry

An advanced treatement of topics of current interest in plant /biochemistry, including photosynthesis and carbon metabolism, nitrogen fixation and nitrogen metabolism, structure and function of the higher plant genome, and production of material of economic interest.

3   BIOCH 521 or 765
BIOCH 755
Biochemistry I

An introduction to physical methods, kinetics, and thermodynamics of biochemical reactions and bioenergenetics, chemistry of proteins and amino acids, carbohydrate chemistry, and metabolism. BIOCH 755 and 765 are for students interested in a two-semester comprehensive coverage of biochemistry. For a one-semester course, enroll in BIOCH 521.

3 I Chemical Analysis, one year of organic chemistry, differential and integral calculus
BIOCH 756
Biochemistry I Laboratory

An intensive laboratory course to accompany BIOCH 755. BIOCH 756 and 766 are sequential courses for students interested in a two-semester comprehensive coverage of biochemistry. For a one-semester laboratory course, enroll in BIOCH 522. Six hours lab a week.

2 I BIOCH 755 or concurrent enrollment
BIOCH 757
NMR Laboratory

Basic methods and strategies of nuclear magnetic resonance used in the study of biological molecules. Principles and applications of simple one-dimensional and two-dimensional NMR experiements. Two three-hour laboratories per week. Meets second half of the semester.

1 II BIOCH 755
BIOCH 758
Protein Structure Laboratory

Principles and uses of computational and experimental approaches for studying preptide and protein structure and dynamics: computer modeling and simulation techniques, flourescence and circular dichroism spectroscopes, microcalorimetry, and analytical ultracentrifugation. Two three-hour laboratories per week. Meets first half of semester.

1 II BIOCH 755
BIOCH 765
Biochemistry II

Contuation of BIOCH 755; lipid chemistry and metabolism, amino acid metabolism, nutrition, nucleic acid chemistry and metabolism, integration of biochemical pathways and metabolic control mechanisms.

3 II BIOCH 755
BIOCH 766
Recombinant DNA Laboratory I

Biochemical manipulation of nucleic acids. Isolation and restriction enzyme characterization of plasmid DNA, ligation of DNA fragments to vector DNA, polymerase chain reaction, Souther blot analysis, DNA sequencing and analysis. Two three-hour labs per week. Meets first half of semester.

1 II BIOCH 522
BIOCH 767
Recombinant DNA Laboratory II

Approaches to study of RNA and proteins using recombinant DNA techniques. RNA extraction and affinity isolation of mRNA, Northern blot analysis, cDNA library contruction and screening, bacterial or eukaryotic expression systems, purification and characterization of recombinant proteins, site-directed mutagenesis. Two three-hour labs per week. Meets second half of semester.

1 II BIOCH 522
BIOCH 790
Physical Biochemistry

A survey of biophysical methods most frequently encountered in biochemistry and related disciplines. Emphasizes principles underlying methods used in determining the molecular weight and shape of biopolymers and techniques used in detecting conformational changes in nucleic acids, proteins, and polysaccharides.

3 I MATH 221, CHM 500 and BIOCH 765
BIOCH 799
Problems in Biochemistry

Problems may include laboratory and/or library work in various phases of biochemistry, agricultural chemistry, or nutrition.

Varies I, II and S Background adequate for problems undertaken
BIOCH 806
Biochemistry Seminar

Seminar for graduate students in biochemistry.

0 to 1    
BIOCH 815
Nuclear Magnetic Resonance (NMR) Spectroscopy of Macromolecules

A lecture and laboratory course on 'state-of-the-art' multi-dimensional nuclear magnetic resonance methods and strategies in solving three dimensional structure of peptides, proteins, nucleic acids and other macromolecules.

2    
BIOCH 840
Intermediary Metabolism

On sufficient demand. Metabolic role of carbohydrates, lipids, proteins and amino acids, purines, pyrimidines, vitamins, and hormones: biological oxidations: mechanisms of energy production and utilization.

3   BIOCH 755 and 765
BIOCH 890
Advanced Topics in Biochemistry

Course to present timely topics in Biochemistry.

1 to 3   Consent of instructor
BIOCH 899
Research in Biochemistry I

Research in biochemistry which may be used for preparation of the M.S. thesis.

Varies   Sufficient training for research undertaken
BIOCH 905
Advanced Topics in Plant Biochemistry

Description

3   BIOCH 765
BIOCH 907
Advanced Topics in Insect Biochemistry

In even years. Lectures, readings, and discussion of topics of current interest in insect biochemistry. Topics will include biochemical molecules and processes specific to insects, such as biochemistry of the exoskeleton and regulation of metamorphosis, as well as comparison of insect and mammalian biochemistry.

    BIOCH 521
BIOCH 910
Lipids

In odd years. Chemistry of plant and animal lipids, their occurrence, metabolism, and industrial uses.

2   BIOCH 765
BIOCH 911
Molecular Signal Transduction

In even years. The molecular structure, biochemical role, and interrelationships of signaling molecules such as receptors, G proteins, channels, and adaptor proteins in signal transduction pathways.

3   BIOCH 765
BIOCH 920
Nucleic Acids

In even years. Structure and function of nucleic acids: structures and properties of DNA, RNA, and chromatin; recombinant DNA techniques; mutagenesis and carcinogenesis; protein-nucleic acid interactions; structural influences on replication, transcription, translation, and regulation.

2   BIOCH 765
BIOCH 930
Proteins

In odd years. Lectures and readings on the chemical nature of proteins; fractionation; purification, structure, chemical and physical properties of proteins and amino acids.

2   BIOCH 755 and 765
BIOCH 935
Biochemistry of Cell Regulation

In odd years. Integration of biochemical pathways and molecular mechanisms regulating cell growth, movement, differentiation, and death. Empnasis on molecular interactions and signaling cascades controlling gene expression, protein synthesis and folding, proteolysis, cytoskeleton, cell cycle, cell survival, and apoptosis.

3   BIOCH 765
BIOCH 940
Chemistry of Carbohydrates

On sufficient demand. Lectures and readings on structural chemistry of carbohydrates, their general properties, biological and chemical reactions, and the methods of characterization.

2   BIOCH 755 and 765
BIOCH 950
Advanced Topics in Protein Science

In even years. Recent advances in protein biochemistry, including protein structure determination, dynamics, folding, stability, enzyme mechanism and regulation.

3   BIOCH 765
BIOCH 997
Postdoctoral Research in Biochemistry

Advanced level research in collaboration with a faculty member, involving projects in any area of biochemistry. Post-graduate training in first three years beyond doctorate.

1 to 12   Ph.D. or equivalent
BIOCH 999
Research in Biochemistry II

Research in biochemsitry which may be used for preparation of the Ph.D. thesis.

Varies   Sufficient training for research undertaken