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Division of Biology

Stephen K. Chapes, Professor

chapes

Associate Director, Johnson Cancer Research Center
Director, Undergraduate Office,
Kansas IDeA Network of Biomedical Research Excellence

Contact information

239C Chalmers Hall
(785) 532-6795
skcbiol@ksu.edu

Education

Ph.D., 1981, University of Illinois-Urbana Champaign, Department of Pathobiology.

Area(s) of Specialization

Immunology

Courses

BIOL 670  Immunology
BIOL 671  Immunology Lab
BIOL 840  Molecular and Cellular Immunology
BIOL 850  Advances in Immunology-Inflammatory Cells

Research Focus

Projects in my laboratory focus on macrophages, inflammatory cells and other white blood cells. I am interested in the function of these cells, the role these cells have in infectious diseases and the impact of space flight on these cells.

Publications

Von Ohlen T, Luce-Fedrow A, Ortega, M T Ganta RR, Chapes SK. 2012. Identification of critical host mitochondrion-associated genes during Ehrlichia chaffeensis infections. Infect Immun 80: 3576-3586. (PMID:22851751; PMC3457586) Spotlighted Paper and Cover Feature.

Drolia, R, Von Ohlen T, Chapes SK. 2013. Ehrlichia chaffeensis replication sites in adult Drosophila melanogaster. Int J Med Microbiol 303: 40– 49. (PMID:23306065;PMC3558598) Also see the RNAi screening center blog.

Chitko-McKown, CG, Chapes SK, Miller LC, Riggs PK, Ortega MT, Green BT, McKown RD. 2013. Development and characterization of two porcine monocyte-derived macrophage cell lines. Results in Immunology. 3:26-32 (PMID:23610747; PMC3631004).

Chapes, SK,Velasquez SE. 2013. Assessment of the impact of the Kansas IDeA Network of Biomedical Research Excellence program on undergraduate participation in research. J Microbiol and Biology Education. 14:47-57 (PMID:23858353; PMC3706165).

Chapes SK, Ortega MT. 2013. Understanding macrophage differentiation during space flight: The importance of ground-based experiments before space flight. Recent Patents on Space Technology. 3:40-47. (PMID:24432200; PMC3890248).

Dib LH, Ortega MT, Fleming SD, Chapes SK*, Melgarejo TL*. 2014. Bone Marrow Leptin Signaling Mediates Obesity-Associated Adipose Tissue Inflammation in Male Mice. Endocrinology. 155:40-46. (PMID:24169547; PMC3868799) *Co-Sr. Investigators. Also see the counterpoint article and rebuttal in Endocrinology, 155:12–14, 2014.

Xie L, Fu Q, Ortega MT, Zhou L, Rasmussen D, O'Keefe J, Zhang KK,  Chapes SK. 2014. Overexpression of IL-10 in C2D macrophages promotes a macrophage phenotypic switch in adipose tissue environments. PloS ONE 9(1):e86541.doi: 10.1371/journal.pone.0086541 (PMID 24466141; PMC3897709).

View the complete publication list in NCBI