http://www.ksu.edu/biology K-State Division of Biology

Passarelli

A. Lorena Passarelli

Associate Professor
Associate Director for Student Development

Ph.D. 1993, The University of Georgia
Genetics

  Molecular biology of baculoviruses: gene regulation and viral pathogenesis

269 Chalmers Hall
(785) 532-3195
lpassar@ksu.edu

Molecular Cellular Developmental Biology Web


Selected Research Publications

Lehiy, C, W. Wu, M. F. Berretta and, A. L. Passarelli.  2013.  Autographa californica M nucleopolyhedrovirus open reading frame 109 affects infectious budded virus production and nucleocapsid envelopment in the nucleus of cells.  Virology 435: 442-452.

Passarelli, A. L. 2013. Late genes. Brenner’s Encyclopedia of Genetics, 2nd edition. Maloy, S. and K. Hughes. Elsevier. P. 195-197.
http://dx.doi.org/10.1016/B978-0-12-374984-0.00847-0, ISBN: 978-0-12-374984-0

Wu, W. and A. L. Passarelli.  Autographa californica M nucleopolyhedrovirus ac79 encodes an early gene with structural similarities to UvrC and intron-encoded endonucleases that is required for efficient budded virus production.  2012.  J. Virol., 86: 5614-5625. 

Huang, N., W. Wu, K. Yang, A. L. Passarelli, G. F. Rohrmann, and R. J. Clem.  2011. Baculovirus infection induces a DNA response that is required for efficient viral replication J. Virol.  85: 12547-12556. 

Passarelli, A. L. 2011.  Barriers to success: how baculoviruses establish systemic infectionsVirology 411:383-392.

Wu, W. and A.L. Passarelli.  2010.  Autographa californica M nucleopolyhedrovirus Ac92 (ORF92, P33) is required for budded virus production and multiply-enveloped occlusion-derived virus formation J. Virol.  84: 12351-12361.

Means, J.C. and A.L. Passarelli.  2010.  Viral fibroblast growth factor, matrix metalloproteases, and caspases are associated with enhancing infection by baculovirusesProc. Natl. Acad. Sci. USA.  107:9825-9830.

Lehiy, C.J., O. Martinez, and A.L. Passarelli. 2009. Virion-associated viral fibroblast growth factor stimulates cell motility. Virology 395:152-160.

Michalsky, R., P.H. Pfromm, P. Czermak, C.M. Sorensen, and A.L. Passarelli. 2008.  Effects of temperature and shear force on infectivity of the baculovirus Autographa californica M nucleopolyhedrovirusJ. Virol. Methods 153(2):90-96.

Crouch, E.A ., L.A. Cox, K. Morales, A.L. Passarelli.  2007. Inter-subunit interactions of the Autographa californica M nucleopolyhedrovirus RNA polymeraseVirology 367:265-274. 

Detvisitsakun, C., E.L. Cain, and A.L. Passarelli.  2007.  The Autographa californica M nucleopolyhedrovirus fibroblast growth factor accelerates host mortality.  Virology 365:70-78. 

Passarelli, A.L.  2007.  Baculovirus RNA polymerase: Activities, composition and evolution.   Virologica Sinica 22:94-107.   

Passarelli, A.L. and L.A. Guarino.  2007.  Baculovirus late and very late gene regulationCurrent Drug Targets 8:1103-1115.

Deng, Y., Y. Dong, V. Thodima, R.J. Clem, A. L. Passarelli. 2006.  Analysis and functional annotation of expressed sequence tags from the fall armyworm Spodoptera frugiperda.  BioMed Central Genomics 7:264-274. 

Berretta, M.F. and A.L. Passarelli.  2006.  Function of Spodoptera exigua nucleopolyhedrovirus late gene expression factors in the insect cell line SF-21.  Virology 355:82-93.

Berretta, M.F., M. Deshpande, E.A., Crouch, and A.L. Passarelli.  2006.  Functional characterization of Bombyx mori nucleopolyhedrovirus late gene transcription and genome replication factors in the non-permissive insect cell line SF-21Virology 348:175-189.

Detvisitsakun, C., E.L. Hutfless, M.F. Berretta, and A.L. Passarelli.   2006.  Analysis of a baculovirus lacking a functional viral fibroblast growth factor homologVirology 346:258-265. 

Devisitsakun, C., M.F. Berretta, C. Lehiy, and A.L. Passarelli.  2005.  Stimulation of cell motility by a viral fibroblast growth factor homolog:Proposal for a role in viral pathogenesisVirology 336:308-317.

Crouch, E.A. and A.L. Passarelli.  2005.  Effects of baculovirus transactivators IE-1 and IE-2 on the Drosophila heat shock promoter in twoinsect cell linesArch. Virol. 150:1563-1578

Titterington, J.S., T.K. Nun, and A.L. Passarelli.  2003.  Functional dissection of the baculovirus late expression factor-8:  Sequence requirements for late gene promoter activation.   J. Gen. Virol. 84:1817-1826.

Crouch, E.A. and A.L. Passarelli.  2002.  Genetic Requirements for Homologous Recombination in Autographa californica NucleopolyhedrovirusJ Virol. 76: 9323-34.

Complete list of publications at PubMed

 


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