K-State Division of Biology


Alexander Beeser

Assistant Professor

Ph.D. 2000, University of Tennessee, Health Sciences Center


412 Ackert Hall
(785) 532-0193

Molecular Cellular Developmental Biology Web

Selected Research Publications

Thullberg, M., A. Gad, A. Beeser, J Chernoff, and S. Stromblad.  2006.  The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity. Oncogene [ Epub ahead of print].

Beeser, A. and J. Chernoff.  2005.  Production and use of a cell permeable inhibitor of group A Paks (TAT-PID) to analyze signal transduction. Methods 37: 203-207

Beeser, A., Z.M. Jaffer, C. Hofmann and J. Chernoff.  2005.  Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factorsJ. BioI. Chem. 280: 36609-36615

Reynolds, L.F., C. de Bettignies, T. Norton, A. Beeser, J. Chernoff, and V.L. Tybulewicz.  2004.  Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1J. BioI. Chem. 279: 18239-46.

Beeser, A., and J. Chernoff. 2003.  Rho GTPases and cell motility. In Rho GTPases, Landes Biosciences, edited by M. Symons, pp. 141-154.  ISBN: 1-58706-199-6, epub.

Cheung, W.L., K. Ajiro, K. Samejima, M. Kloc, P. Cheung, C.A. Mizzen, A. Beeser, L.D. Etkin, J. Chernoff, W.C. Earnshaw, and C.D. Allis.  2003.  Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinaseCell 113: 507-517.

Cotteret, S., Z.M. Jaffer, A. Beeser, and J. Chernoff.  2003.  p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.
Mol. Cell. Biol. 23: 5526-5539.

Penzes, P., A. Beeser, J. Chernoff, M.R. Schiller, B.A. Eipper, R.E. Mains, and R.L. Huganir.  2003.  Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin. Neuron 37: 263-274.

Xiao, G-H., A. Beeser, J. Chernoff, and J.R. Testa.  2002.  p21-activated kinase links Rac/Cdc42 signaling to merlin. J. BioI. Chem. 277: 883-886.

Beeser, A.E. and T.G. Cooper.  2000.  The dual-specificity protein phosphatase Yvh1p regulates sporulation, growth, and glycogen accumulation independently of catalytic activity in Saccharomyces cerevisiae via the cyclic AMP-dependent protein kinase cascade.  J. Bacteriol. 182: 3517-528.

Scott, S., R. Dorrington, V. Svetlov, A.E. Beeser, M. Distler, and T.G. Cooper.  2000.  Functional domain mapping and subcellular distribution of Dal82p in Saccharomyces cerevisiae. J. Biol. Chem. 275: 7198-7204.

Beeser, A.E. and T.G. Cooper.  1999.  The dual-specificity protein phosphatase Yvh1p acts upstream of the protein kinase mck1p in promoting spore development in Saccharomyces cerevisiae. J. Bacteriol. 181: 5219-5224.

Beeser, A.E. and T.G. Cooper.  1999.  Control of nitrogen catabolite repression is not affected by the tRNAGln-CUU mutation, which results in constitutive pseudohyphal growth of Saccharomyces cerevisiae. J. Bacteriol. 181: 2472-2476.

Park, H-D, A.E. Beeser, M.J. Clancy, and T.G. Cooper.  1996.  The S. cerevisiae nitrogen starvation-induced Yvh1p and Ptp2p phosphatases play a role in control of sporulation.
Yeast 15: 1135-1151.

Complete List of Research Publications -(PDF)

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