Xuemin
Wang
Professor of Biochemistry
Signal transduction and lipid messengers in plant growth, development,
and stress responses: Regulation and cellular function of phospholipases;
Membrane metabolite profiling and molecular manipulation.
B.S. 1982 Huazhong Agri. University
M.S. 1984 The Ohio State University
Ph.D. 1987 University of Kentucky
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Research in my laboratory concerns signal
transduction processes that regulate plant growth, development, and stress
responses. The current focus is on the role of phospholipases and lipid-derived
messengers in signaling cascades. Specifically, we are interested in: i)
identifying and characterizing enzymes that generate lipid messengers,
ii) defining downstream targets of lipid signaling pathways, iii) elucidating
the relationship and networks of different signaling processes in hormonal
and stress responses, and iv) determining the physiological functions of
lipid-mediated signaling. In addition, we are applying knowledge gained
from the above studies to manipulating crop plants for improving stress
tolerance and productivity. Integrated approaches of molecular biology,
biochemistry, cell biology, stress physiology, functional genomics, and
metabolomics are employed in our research.
Selected Publications:
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Y. Sang, S. Zheng, W. Li, B. Huang, and X. Wang. Regulation of plant water
loss by manipulating the expression of phospholipase D. Plant J. 28:135-144
(2001).
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C. Wang and X. Wang. A novel phospholipase D of Arabidopsis that is activated
by oleic acid and associated with the plasma membrane. Plant Physiol.
127:1102-1112 (2001).
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C. Wang, C. Zien, M. Afitlhile, R. Welti, D.F. Hildebrand, and X. Wang.
Involvement of phospholipase D in wound-induced accumulation of jasmonic
acid in Arabidopsis. Plant Cell. 12:2237-2246 (2000).
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L. Zheng, R. Krishnamoorthi, M. Zolkiewski, and X. Wang. Distinct calcium
binding properties of novel C2 domains of plant phospholipase Dalpha and
beta. J. Biol Chem. 275:19700-19706 (2000).
Complete Publication
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Lipidomics
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